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| Product | Description | |
|---|---|---|
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor , with an IC 50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC 50 in the low nM range (26.3 nM). Anticonvulsant activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135278-54-4. Pack Sizes: 1 mg. Product ID: HY-107701. |  |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a potent and selective NMDA antagonist with > 500-fold selectivity over kainate and AMPA receptors (IC50 = 2.7 and 3 μM, respectively). CGP 78608 exhibits an anticonvulsant effect in vivo following systemic administration. Synonyms: CGP78608 hydrochloride; CGP-78608 hydrochloride; [ (1S) -1-[[ (7-Bromo-1, 2, 3, 4-tetrahydro-2, 3-dioxo-5-quinoxalinyl) methyl]amino]ethyl]phosphonic acid hydrochloride; Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochloride (1:1); (S)-(1-(((7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1135278-54-4. Molecular formula: C11H13BrN3O5P.HCl. Mole weight: 414.58. |  |
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