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| Product | Description | |
|---|---|---|
| CGP 7930 | CGP 7930. Group: Biochemicals. Grades: Purified. CAS No. 57717-80-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CGP 7930 (GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930) | A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 57717-80-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP7930 | CGP7930 is a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB. It increases the potency and efficacy of GABA at both native and recombinant GABAB receptors with EC50 values of 5.37 and 4.60μM respectively. It also enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons. It reduces operant self-administration of ethanol and cocaine in rats. Uses: Cgp7930 has anxiolytic effects in animal studies, and has a synergistic effect with gabab agonists such as baclofen and ghb. it reduces operant self-administration of ethanol and cocaine in rats. Synonyms: 3,5-Bis(1,1-dimethylethyl)-4-hydroxy-beta,beta-dimethylbenzenepropanol;2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol;3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol;CGP7930; CGP-7930; CGP 7930. Grades: >98 %. CAS No. 57717-80-3. Molecular formula: C19H32O2. Mole weight: 292.46. |  |
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