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| Product | Description | |
|---|---|---|
| CGP35348 | CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC 50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only [1]. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123690-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103530. |  |
| CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348) | A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| CGP 35348 | CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Synonyms: CGP35348; CGP-35348; (3-Aminopropyl) (diethoxymethyl)phosphinic acid. CAS No. 123690-79-9. Molecular formula: C8H20NO4P. Mole weight: 225.22. |  |
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