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| Product | Description | |
|---|---|---|
| CH7057288 | CH7057288 is a potent and selective TRK inhibitor. CH7057288 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095616-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107362. |  |
| CH7057288 | CH7057288 is a selective TRK inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CH7057288; CH-7057288; CH 7057288. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2095616-82-1. Molecular formula: C32H31N3O5S. Mole weight: 569.68. Purity: >98%. IUPACName: N-(tert-butyl)-2-((6,6-dimethyl-8-(methylsulfonamido)-11-oxo-6,11-dihydronaphtho[2,3-b]benzofuran-3-yl)ethynyl)-6-methylisonicotinamide. Canonical SMILES: CS(NC1=CC=C2C(C(C)(C)C(OC3=CC(C#CC4=NC(C)=CC(C(NC(C)(C)C)=O)=C4)=CC=C35)=C5C2=O)=C1)(=O)=O. Product ID: ACM2095616821. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CH7057288 | CH7057288 is a selective TRK inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth with IC50 values of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB, and TRKC respectively. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer. Synonyms: N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide; HY-107362; CS-0028214; RCH. CAS No. 2095616-82-1. Molecular formula: C32H31N3O5S. Mole weight: 569.67. |  |
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