Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| CHIR99021 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CHIR99021 HCl | CHIR99021, also known as CT99021, is a GSK-3α/β inhibitor (IC50= 10 nM/6.7 nM) with antiproliferative activity in vitro and in vivo. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells. Synonyms: 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile hydrochloride; CHIR99021 HCl; CHIR99021 hydrochloride; CHIR99021; CHIR-99021; CHIR 99021; CT99021; CT-99021; CT 99021. CAS No. 1797989-42-4. Molecular formula: C22H19Cl3N8. Mole weight: 501.8. |  |
| InSolution GSK-3 Inhibitor XVI, CHIR99021 - CAS 252917-06-9 | GSK-3 Inhibitor XVI, CHIR99021, CAS 252917-06-9, is a 25 mM solution in DMSO. A cell-permeable, ATP-competitive inhibitor of GSK-3 (IC?? = 10 & 6.7 nM for GSK-3? and GSK-3?, respectively). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 77675 | CGP 77675 is a potent Src kinase inhibitor. It can be used to maintain mouse embryonic stem cell (mESC) in combination with CHIR99021. Uses: Protein kinase inhibitors. Synonyms: CGP-77675; 1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol. Grades: >98%. CAS No. 234772-64-6. Molecular formula: C26H29N5O2. Mole weight: 443.55. | |
| CHIR-99021 | A potent and highly selective inhibitor of glycogen synthase kinase-3beta (GSK-3b) (IC50 = 6.7nM). CHIR99021 has been shown to allow for long-term expansion of murine embryonic stem cells in a chemically-defined medium in conjunction with MEK/MAPK inhibitor PD184352 and fibroblast growth factor receptor (FGFR) inhibitor SU5402. Group: Biochemicals. Alternative Names: 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2- yl) pyrimidin-2-yl) amino) ethyl) amino) nicotinonitrile; CT99021; CHIR 911. Grades: Highly Purified. CAS No. 252917-06-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| CHIR 99021 dihydrochloride | CHIR 99021 is a potent glycogen synthase kinase GSK-3 inhibitor. Synonyms: CHIR-99021 dihydrochloride; CHIR99021 dihydrochloride; CT-99021 dihydrochloride; CT 99021 dihydrochloride; CT99021 dihydrochloride; GSK-3 Inhibitor XVI dihydrochloride; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile dihydrochloride. Grades: 99%. CAS No. 2109414-84-6. Molecular formula: C22H18Cl2N8.2HCl. Mole weight: 538.26. | |
| CHIR 99021 trihydrochloride | CHIR 99021 is a highly selective GSK-3 inhibitor. CHIR 99021 is used in the treatment of parkinsonism. Uses: The treatment of parkinsonism. Synonyms: CHIR-99021 trihydrochloride; CHIR 99021 trihydrochloride; CHIR99021 trihydrochloride; 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile trihydrochloride. Grades: ≥98% by HPLC. CAS No. 1782235-14-6. Molecular formula: C22H18Cl2N8.3HCl. Mole weight: 574.72. | |
| PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III) | A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC50 = 0.33nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells. PD 325901 is an inhibitor of mitogen activated protein kinase kinase (MEK or MAPKK). The potency, solubility and effectiveness of PD 325901 are greatly improved compared to PD 184352 (CI-1040). Group: Biochemicals. Alternative Names: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2[(2-fluoro-4-iodophenyl)amino]-benzamide; PD 0325901, MEK1/2 Inhibitor III. Grades: Highly Purified. CAS No. 391210-10-9. Pack Sizes: 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| trans 2-Phenylcyclopropylamine Hydrochloride (Tranylcypromine, trans 2-Amino-1-phenyl-cyclopropane Hydrochloride) | A non-selective inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Tranylcypromine; trans 2-Amino-1-phenyl-cyclopropane Hydrochloride. Grades: Highly Purified. CAS No. 1986-47-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Tranylcypromine Hemisulfate (Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA) | An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA. Grades: Highly Purified. CAS No. 13492-01-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| WH-4-023 | WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 values of 2 nM and 6 nM for Lck and Src kinase respectively. In combination with PD 0325901, CHIR99021 and SB-590885, WH-4-023 was found to support self-renewal of naive human embryonic stem cells (hESCs). Synonyms: KIN001-112; KIN112; 2,6-dimethylphenyl (2,4-dimethoxyphenyl)(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)carbamate. Grades: >98%. CAS No. 837422-57-8. Molecular formula: C32H36N6O4. Mole weight: 568.67. | |
Our database is helping our users find suppliers everyday.
