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1-Hydroxytetraphenylcyclopentadienyl (tetraphenyl-2, 4-cyclopentadien-1-one)-mu-hydrotetracarbonyldiruthenium (II)
In conjugation with lipase, ruthenium catalyst used in the asymmetric transformation of ketones and enol acetates into chiral acetates. Dynamic kinetic resolution resulting from the ruthenium catalyzed racemization of enzymatically- resolved substrates. Conversion of secondary amines to primary amines in the presence of ammonia. Co-catalyt for aerobic lactonization of diols. Group: Ruthenium series catalysts. Alternative Names: Shvo's catalyst. CAS No. 104439-77-2. Molecular formula: C62H41O6Ru2. Mole weight: 1084.1. Appearance: Powder. Purity: 0.98. Canonical SMILES: [C-]#[O+]. [C-]#[O+]. [C-]#[O+]. [C-]#[O+]. C1=CC=C (C=C1) C2=C (C (=O) C (=C2C3=CC=CC=C3) C4=CC=CC=C4) C5=CC=CC=C5. C1=CC=C (C=C1) [C]2[C] ([C] ([C] ([C]2C3=CC=CC=C3) O) C4=CC=CC=C4) C5=CC=CC=C5. [Ru]. [Ru]. Catalog: ACM104439772-1.
(1R,2R)-rel-trans-1,2-Cyclopentanediol
(1R,2R)-rel-trans-1,2-Cyclopentanediol is a building block for the synthesis of chiral phosphine ligands. It can also be used to prepare benzoquinolines and benzoindoles via heterocyclization of naphthylamines with diols catalyzed by iridium chloride/BINAP. Group: Biochemicals. Grades: Highly Purified. CAS No. 5057-99-8. Pack Sizes: 1g, 10g. Molecular Formula: C5H10O2, Molecular Weight: 102.13. US Biological Life Sciences.
Worldwide
3,6-Octanedione
It is involved in enzymic stereoselective reduction of diketones into chiraldiols. Group: Biochemicals. Grades: Highly Purified. CAS No. 2955-65-9. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
(S)-(+)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate, min. 98% [(S)-TiPSY]
Chiral phosphoric acid catalyst used for the highly enantioselective Friedel-Crafts reaction of indoles with imines. Chiral phosphoric acid catalyst used for the highly enantioselective Friedel-Crafts reaction of pyrrole derivatives with N-acyl imines. Chiral phosphoric acid catalyst used for the enantioselective transfer hydrogenation of hydroxylactams providing enantioenriched tetrahydro-β-carbolines (in dioxane) at room temperature (up to 94% yield, 90% ee). [Rh2(OAc)4]/chiral phosphoric acid catalyst used for the enantioselective symmetric, three-component reaction of diazo compounds with imines and water yielding β-amino-α-hydroxy acid derivatives. Enantioselective desymmetrization of prochiral allenic diols via cooperative catalysis of Pd(OAc)2 and a chiral phosphoric acid. Group: Phosphorus catalysts. Alternative Names: (11bS)-4-Hydroxy-2,6-bis(triphenylsilyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine4-oxide; Phosphoric acid (aR)-3,3'-bis(triphenylsilyl)-1,1'-binaphthalene-2,2'-diyl ester; (11bS)-4-Hydroxy-2,6-bis(triphenylsilyl)dinaphtho-[2,1-d1 inverted exclamation marka,2 inverted exclamation markaf]-[1,3,2]-dioxaphosphepin 4-oxide; (S)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate. CAS No. 929097-92-7. Molecular formula: C56H41O4PSi2. Mole weight: 865.084g/mol. IUPACName: (13-hydroxy-1
1,1'-Bi-2-naphthol
1,1'-Bi-2-naphthol is used as a chiral ligand in alkynylation, Diels-Alder and assymmetric Michael addition reactions. Group: Heterocyclic organic compound. Alternative Names: Q-103560; AB1003930; (S)-(-)-1,1'-Bi-2-naphthol; s-(-); bi-2-naphthol; (S)-(-)-1,1 inverted exclamation marka-Binaphthalene-2,2 inverted exclamation marka-diol; CHEMBL138718; (+)-2,2 inverted exclamation marka-Dihydroxy-1,1 inverted exclamation marka-dinaphthyl; s-binol; F0001-0669. CAS No. 602-09-5. Molecular formula: C20H14O2. Mole weight: 286.33g/mol. IUPACName: 1-(2-hydroxynaphthalen-1-yl)naphthalen-2-ol. Canonical SMILES: C1=CC=C2C (=C1)C=CC (=C2C3=C (C=CC4=CC=CC=C43)O)O. ECNumber: 606-050-5. Catalog: ACM602095.
2-Iodobenzene-1,3-diol is involved in the facile synthesis of amino acid-derived novel chiral hypervalent iodine(V) reagents. Group: Biochemicals. Grades: Highly Purified. CAS No. 41046-67-7. Pack Sizes: 250mg, 500mg. Molecular Formula: C6H5IO2. US Biological Life Sciences.
Isomannide (CAS# 641-74-7) is a reagent used in the synthesis of new isomannide-based peptidomimetic as human tissue kallikrein 1 inhibitor using Ugi multicomponent reaction. It also functions as a chiral ligand for stereoselective synthesis. Synonyms: D-Mannitol, 1,4:3,6-dianhydro-; 1,4:3,6-Dianhydro-D-mannitol; Mannitol, 1,4:3,6-dianhydro-, D-; (+)-Isomannide; (3R,3aR,6R,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol; 1,4:3,6-Dianhydromannitol; D-Isomannide; Dianhydromannitol; NSC 270938. Grades: ≥95%. CAS No. 641-74-7. Molecular formula: C6H10O4. Mole weight: 146.14.
(R)-(-)-1,3-Butanediol
(R) - (- ) - 1, 3- Butanediol is a chiral reagent used in the synthesis of pharmaceuticals including the preparation of (- ) - tarchonanthuslactone, a δ- lactone skeleton based compound with antiroliferative activity on cancer cell. Group: Biochemicals. Alternative Names: (3R)-1,3-Butanediol; (-)-1,3-Butanediol; (R)-(-)-1,3-Butanediol; (R)-1,3-Butanediol; L-Butane-1,3-diol. Grades: Highly Purified. CAS No. 6290-3-5. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C?H??O?, Molecular Weight: 90.12. US Biological Life Sciences.
(R)-3, 3'-Bis(3, 5-diisopropylphenyl)-[1, 1'-binapthalene]-2, 2'-diol, also known as (R)-BINAP, is an important chiral ligand used in asymmetric synthesis of organic compounds. It is a widely used compound in chemical and pharmaceutical industries due to its ability to catalyze a variety of reactions with high enantioselectivity. This review will discuss the synthesis of (R)-BINAP, its scientific research applications, its mechanism of action, its biochemical and physiological effects, the advantages and limitations for lab experiments, and the potential future directions of research. Uses: (r)-binap is widely used in asymmetric synthesis of various organic compounds, including chiral drugs, natural products, and polymers. it is particularly useful in the synthesis of polycyclic compounds and chiral alcohols, and has been used in the synthesis of a variety of drugs, including the antimalarial drug artemisinin, the anti-cancer drug paclitaxel, and the anti-hiv drug tenofovir. in addit. Group: Chiral binol ligands. CAS No. 1435948-31-4. Molecular formula: C44H46O2. Mole weight: 606.8 g/mol. IUPACName: 3-[3,5-di(propan-2-yl)phenyl]-1-[3-[3,5-di(propan-2-yl)phenyl]-2-hydroxynaphthalen-1-yl]naphthalen-2-ol. Canonical SMILES: CC (C)C1=CC (=CC (=C1)C2=CC3=CC=CC=C3C (=C2O)C4=C (C (=CC5=CC=CC=C54)C6=CC (=CC (=C6)C (C)C)C (C)C)O)C (C)C. Catalog: ACM1435948314-1.
(R)-3, 3'-Bis(diphenylphosphanyl)-[1, 1'-binapthalene]-2, 2'-diol (R-BDP-BNP-diol) is a synthetic, chiral phosphine ligand widely used in asymmetric synthesis. It is a chiral, non-racemic ligand that can be used to induce enantioselectivity in various chemical reactions. R-BDP-BNP-diol has been used in a variety of organic transformations, such as hydrogenation, hydroformylation, and hydrocyanation. It has also been used in a range of catalytic asymmetric reactions, including hydroboration, hydroamination, and hydrozirconation. Uses: R-bdp-bnp-diol has been used in a variety of scientific research applications, such as asymmetric synthesis, catalysis, and drug discovery. it has been used in the synthesis of chiral drugs, such as the anti-cancer drug bortezomib, as well as in the synthesis of chiral catalysts for asymmetric hydrogenation and hydroformylation reactions. in addition, r-bdp-bnp-diol has been used in the synthesis of chiral building blocks for drug discovery. Group: Chiral binol ligands. CAS No. 911383-51-2. Molecular formula: C44H32O2P2. Mole weight: 654.7 g/mol. IUPACName: 3-diphenylphosphanyl-1-(3-diphenylphosphanyl-2-hydroxynaphthalen-1-yl)naphthalen-2-ol. Canonical SMILES: C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC4=CC=CC=C4C (=C3O)C5=C (C (=CC6=CC=CC=C65)P (C7=CC=CC=C7)C8=CC=CC=C8)O. Catalog: ACM911383512-1.
(R,R)-(+)-Hydrobenzoin is a chiral vicinal diol and an organic catalyst. (R,R)-(+)-Hydrobenzoin is used in asymmetric catalytic reactions [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 52340-78-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-59125.
(S)-(-)-1-Phenylethanol can be prepared from acetophenone via enantioselective bioreduction in the presence of Rhizopus arrhizus as a biocatalyst. Uses: (s)-(-)-1-phenylethanol can be used as: a starting material to prepare (1s,3r,4s)-1-methyl-3,4-diphenyl-3,4-dihydro-1h-isochromene-3,4-diol (a cyclic hemiacetal) by reacting with benzil via dilithiation reaction. a chiral solvent in the symmetric synthesis of substituted spiroundecenetriones via amino acid-catalyzed domino knoevenagel/diels-alder reactions. Group: Chiral alcohols & ligands. Alternative Names: (S)-(-)-sec-Phenylethyl alcohol, (-)-Methyl phenyl carbinol, (S)-(-)-α-Methylbenzyl alcohol. CAS No. 1445-91-6. Molecular formula: C8H10O. Mole weight: 122.16. Canonical SMILES: C[C@H](O)c1ccccc1. Density: 1.012 g/mL at 20 °C (lit.). Catalog: ACM1445916-1.