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This product with the indicated enzyme activity was briefly purified from engineered E. coli. Group: Enzymes. Enzyme Commission Number: EC 4.1.2.X. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. Chloroacetaldehyde Aldolase. Pack: 100ml. Cat No: NATE-1849.
Bromochloroacetalde hyde. Group: Biochemicals. Alternative Names: 2-Bromo-2-chloroacetaldehyde. Grades: Highly Purified. CAS No. 98136-99-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C2H2BrClO. US Biological Life Sciences.
Worldwide
fluorothreonine transaldolase
A pyridoxal phosphate protein. Can also convert chloroacetaldehyde into4-chloro-L-threonine. Unlike EC 2.1.2.1, glycine hydroxymethyltransferase, does not use glycine as a substrate. Group: Enzymes. Enzyme Commission Number: EC 2.2.1.8. CAS No. 403503-13-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2035; fluorothreonine transaldolase; EC 2.2.1.8; 403503-13-9. Cat No: EXWM-2035.
Palifosfamide
Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lysine for stability, palifosfamide irreversibly alkylates and cross-links DNA through GC base pairs, resulting in irreparable 7-atom inter-strand cross-links; inhibition of DNA replication and cell death follow. Unlike ifosfamide, this agent is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. In addition, because palifosfamide does not require activation by aldehyde dehydrogenase, it may overcome the tumor resistance seen with ifosfamide. Synonyms: Isophosphamide mustard; Isophosphoramide mustard; IPAM; bis(2-chloroethylamino)phosphinic acid. Grades: ≥ 98%. CAS No. 31645-39-3. Molecular formula: C4H11Cl2N2O2P. Mole weight: 221.018.
Palifosfamide tromethamine
Palifosfamide tromethamine is a synthetic mustard compound with potential antineoplastic activity. It is an active metabolite of ifosfamide covalently linked to the amino acid lysine for stability. It inhibits DNA replication and cell death. It is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. It may overcome the tumor resistance seen with ifosfamide. It was developed by Dekk-Tec and in clinic phase 3 with no progress. Uses: Palifosfamide tromethamine has potential antineoplastic activity. Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol;Bis(2-chloroethylamino)phosphinic acid;ZIO201;ZIO-201;NSC297900;NSC-297900;N,N'-Bis(2-chloroethyl)phosphorodiamidic acid. Grades: >98%. CAS No. 1070409-31-2. Molecular formula: C8H22Cl2N3O5P. Mole weight: 342.15.
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