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| Product | Description | |
|---|---|---|
| Chondroitin disaccharide 4S sodium salt | Chondroitin disaccharide 4S sodium salt emerging as an indispensable consituent primarily employed in the research of connective tissue ailments. Synonyms: Dermatan 4-sulfate disaccharide sodium salt. Molecular formula: C14H19NO14SNa2. Mole weight: 503.34. |  |
| Chondroitin disaccharide 6S sodium salt | Chondroitin disaccharide 6S sodium salt is a pivotal compound with application in osteoarthritis study becoming prominent. By virtue of its organic origin, this compound embodies both anti-inflammatory and chondroprotective virtues, rendering it an invaluable pharmacological alternative in the pursuit of studying afflictions pertaining to joint pathologies. Synonyms: Dermatan sulfate disaccharide sodium salt. Molecular formula: C14H19NO14S 2Na. Mole weight: 503.34. | |
| Chondroitin disaccharide Δdi-6S disodium salt | It is produced by various chondroitin sulfates through the action of chondroitin enzymes ABC, AC-1 and C. Synonyms: Disodium 2-acetamido-2-deoxy-3-O-(4-deoxy-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-D-galactopyranose; Alpha-delta-ua-[1->3]-galnac-6s sodium salt; Chondroitin disaccharide delta-di-6S sodium salt; sodium (3R,4S)-2-((3R,4R,5R,6R)-3-acetamido-2,5-dihydroxy-6-(sulfonatooxymethyl)tetrahydro-2H-pyran-4-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; D-Galactopyranose, 2-(acetylamino)-2-deoxy-3-O-(4-deoxy-L-threo-hex-4-enopyranuronosyl)-, 6-(hydrogen sulfate), sodium salt (1:2). Grades: ≥98%. CAS No. 136132-72-4. Molecular formula: C14H19NNa2O14S. Mole weight: 503.34. | |
| Chondroitin disaccharide Δdi-disE | Chondroitin disaccharide Δdi-disE: A biomedical product used in the treatment of joint-related conditions. Derived from chondroitin, it aids in repairing and maintaining healthy cartilage. With its anti-inflammatory properties, it alleviates pain caused by arthritis and supports improved joint mobility. CAS No. 1990-26-0. Molecular formula: C14H18NNa3O17S2. Mole weight: 605.39. | |
| Chondroitin disaccharide Δdi-triS | Chondroitin disaccharide Δdi-triS is a crucial component in the biomedical industry, specifically used in the research of joint-related conditions such as osteoarthritis. Its presence assists in maintaining the integrity and flexibility of cartilage. Molecular formula: C14H17NNa4O20S3. Mole weight: 707.44. | |
| Chondroitin disaccharide di-0S sodium salt | It is produced by various chondroitin sulfates through the action of chondroitin enzymes ABC, AC-1 and C. Synonyms: D-Galactose, 2-(acetylamino)-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-, monosodium salt; 2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-D-galactose sodium salt; GlcAb(1-4)GalNAc; α-ΔUA-[1?3]-GalNAc. Grades: ≥95%. CAS No. 136132-69-9. Molecular formula: C14H20NNaO11. Mole weight: 401.30. | |
| Chondroitin disaccharide di-4S disodium salt | Chondroitin disaccharide di-4S disodium salt (CAS# 136144-56-4 ) is a useful research chemical. Synonyms: Chondroitin disaccharide Δdi-4S disodium salt; 4-(Hydrogen sulfate)-2-(acetylamino)-2-deoxy-3-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-D-Galactose Disodium Salt; D-Galactose, 2-(acetylamino)-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-, 4-(hydrogen sulfate), disodium salt; Disodium 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-4-O-sulfonato-D-galactose; α-δUA-[1->3]-GalNAc-4S. Grades: 95 %. CAS No. 136144-56-4. Molecular formula: C14H19NNa2O14S. Mole weight: 503.34. | |
| Chondroitin disaccharide di-6S | Chondroitin disaccharide di-6S is a crucial component in the biomedical industry, commonly used in the development of treatments for various joint-related disorders. It plays a vital role in treating osteoarthritis, reducing pain and inflammation as well as facilitating the regeneration of damaged cartilage. Synonyms: Disodium; (2S,3S,4S,5R,6R)-6-[(3R,4R,5R,6R)-3-acetamido-2,5-dihydroxy-6-(sulfonatooxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate; Chondroitin disaccharide di-6S disodium salt. CAS No. 149458-08-2. Molecular formula: C14H21NNa2O15S. Mole weight: 521.36. | |
| Chondroitin disaccharide di-diSB trisodium salt | It is produced from various chondroitin sulfates by the action of chondroitin enzymes ABC and/or B, and most typically from chondroitin sulfate B (dermatan sulfate). Synonyms: Chondroitin disaccharide (delta-DiSB, sodium salt); 2-Acetamido-2-deoxy-3-O-(2-O-sulfo-beta-D-gluco-4-enepyranosyluronic acid)-4-O-sulfo-D-galactose sodium salt; sodium (3R,4S)-2-((3R,4R,5R,6R)-3-acetamido-2-hydroxy-6-(hydroxymethyl)-5-(sulfonatooxy)tetrahydro-2H-pyran-4-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate. Grades: ≥90%. CAS No. 136132-71-3. Molecular formula: C14H18NNa3O17S2. Mole weight: 605.39. | |
| Chondroitin disaccharide di-diSD trisodium salt | It is produced by various chondroitin sulfates through the action of chondroitin enzyme ABC. Synonyms: Chondroitin disaccharide Δdi-disD Disodium Salt. Grades: ≥95%. CAS No. 149368-03-6. Molecular formula: C14H18NO17S2Na3. Mole weight: 605.39. | |
| Chondroitin disaccharide di-diSE trisodium salt | Chondroitin disaccharide di-diSE trisodium salt is a highly indispensable and pivotal molecule harboring immense utility in the compoundion of pharmacological drugs formulated specifically to study diverse ailments associated with joints. Molecular formula: C14H18NNa3O17S2. Mole weight: 605.39. | |
| Chondroitin disaccharide di-triS tetrasodium salt | Chondroitin Disaccharide Di-TriS Tetrasodium Salt is a crucial biomolecular compound, serving as a foundational substrate for chondroitin sulfate. It exerts pronounced beneficial effects in studying symptoms associated with arthritis, endorsing the rejuvenation of cartilaginous structures and studying discomfort and inflammatory responses. Molecular formula: C14H17NNa4O20S3. Mole weight: 707.44. | |
| Chondroitin disaccharide di-UA2S disodium salt | It is a minor component produced from various chondroitin sulfate by the action of chondroitinase ABC. Synonyms: 2-(Acetylamino)-2-deoxy-3-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-D-galactose Disodium Salt; Chondroitin disaccharide Δdi-UA2S Disodium Salt; sodium (2R,3R,4S)-2-((3R,4R,5R,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; Disodium 2-acetamido-2-deoxy-3-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-D-galactopyranose; α-ΔUA-2S-[1?3]-GalNAc. Grades: 95%. CAS No. 149368-04-7. Molecular formula: C14H19NNa2O14S. Mole weight: 503.34. | |
| unsaturated chondroitin disaccharide hydrolase | The enzyme releases 4-deoxy-4,5-didehydro D-glucuronic acid or 4-deoxy-4,5-didehydro L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1?3) and (1?4) bonds. It prefers the sulfated disaccharides to the unsulfated disaccharides. Group: Enzymes. Synonyms: UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Enzyme Commission Number: EC 3.2.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3864; unsaturated chondroitin disaccharide hydrolase; EC 3.2.1.180; UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Cat No: EXWM-3864. |  |
| chondroitin AC lyase | Acts on chondroitin 4-sulfate and chondroitin 6-sulfate, but less well on hyaluronate. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycan source. Group: Enzymes. Synonyms: chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Enzyme Commission Number: EC 4.2.2.5. CAS No. 9047-57-8. ChnAC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5104; chondroitin AC lyase; EC 4.2.2.5; 9047-57-8; chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Cat No: EXWM-5104. | |
| Chondroitinase ABC from Proteus vulgaris, Recombinant | Chondroitinase ABC cleaves, via an elimination mechanism, sulfated and non-sulfated polysaccharide chains containing 1-4 linkages between hexosamines and glucuronic acid residues. The reaction yields oligosaccharide products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. The enzyme is active on chondroitin sulfates A and C, chondroitin sulfates B (dermatan sulfate), chondroitin and hyaluronic acid. Applications: Determination of contents of chondroitin sulfates by hplcprocessing animal tissues before further investigationspreparation of chondroitin and hyaluronic acid derived unsaturated disaccharidespreparation of hyaluronic acid derived unsaturated disaccharide. Group: Enzymes. Synonyms: EC 4.2.2.4, chondroitinase; ch. Enzyme Commission Number: EC 4.2.2.20. CAS No. 9024-13-9. Chondroitinase ABC. Mole weight: 117.3 kDa. Activity: > 100 IU/mg (substrate: chondroitin sulfate A). Stability: Expiration is at least 12 months from manufacturing date, kept at -20 °C. Source: E.coli. Species: Proteus vulgaris. EC 4.2.2.4, chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Cat No: NATE-1949. | |
| Chondroitinase AC from Flavobacterium heparinum, Recombinant | Chondroitinase AC from Flavobacteriun heparinum is an eliminase that degrades chondroitin sulfates A and C, but not chondroitin sulfate B. The enzyme cleaves, via an elimination mechanism, both sulfated and non-sulfated polysaccharide chains that contain (1?4)-linkages between hexosamines and glucuronic acid residues. The reaction yields oligosaccharide products, mainly disaccharides, with unsaturated uronic acids that can be detected by UV spectroscopy at 232 nm. Applications: Chondroitinase ac was shown to inhibit melanoma invasion and proliferation, endothelial proliferation, and angiogenesis. chondroitinase ac, but not chondroitinase b, has also been shown t..., and protease activities. ChnAC. Activity: >200 units/mg protein. Appearance: Powder. Storage: Store the product at -20?C. When stored properly and unopened at -20?C, the enzyme has a recommended retest date of 2 years. After reconstitution, the product may be kept at 4?C for 4 days, but it is recommended to store the solution in working aliquots at -20 ?C. Form: The enzyme is supplied as a lyophilized powder containing potassium phosphate, NaCl, and a stabilizer. Source: E. coli. Species: Flavobacterium heparinum. chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC; 9047-57-8; EC 4.2.2.5. Cat No: NATE-1738. | |
| Chondroitinase B from Flavobacterium heparinum, Recombinant | In enzymology, a chondroitin B lyase (EC 4.2.2.19) is an enzyme that catalyzes the chemical reaction:Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (deltaUA-GalNAc-4S). This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The enzyme cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroit...preparation of di-and oligo-saccharides of dermatan sulfate. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. Purity: > 90 % by reversed phase HPLC analysis. ChonB. Mole weight: 54,779 Da. Activity: > 550 IU/mg (substrate: dermatan sulfate). Stability: Expiration is 30 months from manufacturing date, frozen at -70°C in aqueous buffers containing Sodium Chloride, Sodium Phosphate and Sucrose 5%. Source: Flavobacterium heparinum. Species: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Pack: vial of 5 ug. Cat No: NATE-0130. | |
| chondroitin B lyase | This is the only lyase that is known to be specific for dermatan sulfate as substrate. The minimum substrate length required for catalysis is a tetrasaccharide. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycansource. Group: Enzymes. Synonyms: chondroitinase B; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5094; chondroitin B lyase; EC 4.2.2.19; 52227-83-5; chondroitinase B; ChonB; ChnB. Cat No: EXWM-5094. | |
| chondroitin-sulfate-ABC endolyase | This enzyme degrades a variety of glycosaminoglycans of the chondroitin-sulfate- and dermatan-sulfate type. Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan sulfate are the best substrates but the enzyme can also act on hyaluronan at a much lower rate. Keratan sulfate, heparan sulfate and heparin are not substrates. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of...ous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I. Enzyme Commission Number: EC 4.2.2.20. CAS No. 9024-13-9. Chondroitinase ABC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5096; chondroitin-sulfate-ABC endolyase; EC 4.2.2.20; 9024-13-9; chondroitinase (ambiguous); chondroitin ABC eliminase (ambiguous); chondroitinase ABC (ambiguous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); cho | |
| chondroitin-sulfate-ABC exolyase | This enzyme degrades a variety of glycosaminoglycans of the chondroitin-sulfate- and dermatan-sulfate type. Chondroitin sulfate, chondroitin-sulfate proteoglycan and dermatan sulfate are the best substrates but the enzyme can also act on hyaluronan at a much lower rate. Keratan sulfate, heparan sulfate and heparin are not substrates. The related enzyme EC 4.2.2.20, chondroitin-sulfate-ABC endolyase, has the same substrate specificity but produces a mixture of oligosaccharides of different sizes that are ultimately degraded totetra- and disaccharides. Both enzymes act by the removal of a relatively acidic C-5 proton of the uronic acid followed by the elimination of a 4-linked ...C lyase (ambiguous); chondroitin sulfate ABC exoeliminase; chondroitin sulfate ABC exolyase; ChS ABC lyase II. Enzyme Commission Number: EC 4.2.2.21. CAS No. 1000607-06-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5097; chondroitin-sulfate-ABC exolyase; EC 4.2.2.21; 1000607-06-6; chondroitinase (ambiguous); chondroitin ABC eliminase (ambiguous); chondroitinase ABC (ambiguous); chondroitin ABC lyase (ambiguous);chondroitin sulfate ABC lyase (ambiguous); ChS ABC lyase (ambiguous); chondroitin sulfate ABC exoeliminase; chondroitin sulfate ABC exolyase; ChS ABC lyase II. Cat No: EXWM-5097. | |
| gellan tetrasaccharide unsaturated glucuronyl hydrolase | The enzyme releases 4-deoxy-4(5)-unsaturated D-glucuronic acid from oligosaccharides produced by polysaccharide lyases, e.g. the tetrasaccharide β-D-4-deoxy-Δ4-GlcAp-(1?4)-β-D-Glcp-(1?4)-α-L-Rhap-(1?3)-β-D-Glcp produced by EC 4.2.2.25, gellan lyase. The enzyme can also hydrolyse unsaturated chondroitin and hyaluronate disaccharides (β-D-4-deoxy-Δ4-GlcAp-(1?3)-β-D-GalNAc, β-D-4-deoxy-Δ4-GlcAp-(1?3)-β-D-GalNAc6S, β-D-4-deoxy-Δ4-GlcAp2S-(1?3)-β-D-GalNAc, β-D-4-deoxy-Δ4-GlcAp-(1?3)-β-D-GlcNAc), preferring the unsulfated disaccharides to the sulfated disaccharides. Group: Enzymes. Synonyms: UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Enzyme Commission Number: EC 3.2.1.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3862; gellan tetrasaccharide unsaturated glucuronyl hydrolase; EC 3.2.1.179; UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Cat No: EXWM-3862. | |
| glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-β-N-acetylgalactosaminyltransferase | Involved in the biosynthesis of chondroitin sulfate. The human form of this enzyme is a bifunctional glycosyltransferase, which also has the 3-β-glucuronosyltransferase (EC 2.4.1.226, N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase) activity required for the synthesis of the chondroitin sulfate disaccharide repeats. Similar chondroitin synthase 'co-polymerases' can be found in Pasteurella multocida and Escherichia coli. Group: Enzymes. Synonyms: N-acetylgalactosaminyltransferase II; UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-β-D-galactosaminylproteoglycan β-1,4-N-acetylgalactosaminyltransferase; cho...curonosyl-N-acetylgalactosaminyl-proteoglycan 4-β-N-acetylgalactosaminyltransferase; EC 2.4.1.175; 96189-40-1; N-acetylgalactosaminyltransferase II; UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-β-D-galactosaminylproteoglycan β-1,4-N-acetylgalactosaminyltransferase; chondroitin synthase; glucuronyl-N-acetylgalactosaminylproteoglycan β-1,4-N-acetylgalactosaminyltransferase; uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II; UDP-N-acetyl-D-galactosamine:β-D-glucuronosyl-(1?3)-N-acetyl-β-D-galactosaminyl-proteoglycan 4-β-N-acetylgalactosaminyltransferase. Cat No: EXWM-2400. | |
| Heparin disaccharide I-P trisodium salt | It is prepared from heparin unsaturated disaccharide I-H by n-propionylation. It is a homologue of disaccharide I-A with the inclusion of a methylene group in the amide acyl group. It does not occur in nature and was devised as an internal standard for HPLC, CZE and CE analysis of heparin/heparin sulfate. It is also ideally suited as an internal standard for HLPC/CZE analysis of chondroitin series, after digestion with chondroitinases. Synonyms: Heparin unsaturated disaccharide I-P trisodium salt; (α-δUA-2S-[1?4]-GlcNCOEt-6S); 2-Deoxy-3-O-[(1R)-4-deoxyhex-4-enopyranuronosyl]-2-(propionylamino)-D-glycero-hexopyranose trisodium salt. Grades: 95%. CAS No. 149368-05-8. Molecular formula: C15H20NNa3O17S2. Mole weight: 619.42. | |
| Hyaluronic acid disaccharide sodium salt | It is the only unsaturated disaccharide produced by hyaluronic acid in response to chondroitin enzymes ABC or AC-1. Synonyms: Hyaluronic acid disaccharide ΔDiHA sodium salt; α-δua-(1?3)-glcnac; Sodium 2-acetamido-2-deoxy-3-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-D-glucose; D-Glucose, 2-(acetylamino)-2-deoxy-3-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, sodium salt (1:1). Grades: ≥98%. CAS No. 149368-06-9. Molecular formula: C14H20NNaO11. Mole weight: 401.30. | |
| N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase | Involved in the biosynthesis of chondroitin and dermatan sulfate. The human chondroitin synthetase is a bifunctional glycosyltransferase, which has the 3-β-glucuronosyltransferase and 4-β-N-acetylgalactosaminyltransferase (EC 2.4.1.175) activities required for the synthesis of the chondroitin sulfate disaccharide repeats. Similar chondroitin synthase 'co-polymerases' can be found in Pasteurella multocida and Escherichia coli. There is also another human protein with apparently only the 3-β-glucuronosyltransferase activity. Group: Enzymes. Synonyms: chondroitin glucuronyltransferase II; α-D-glucuronate:N-acetyl-β-D-galactosaminyl-(1?4)-β-D-glucuronosyl-proteoglycan 3-β-glucuronosyltransferase. Enzyme Commission Number: EC 2.4.1.226. CAS No. 269077-98-7. Chondroitin synthase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2455; N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase; EC 2.4.1.226; 269077-98-7; chondroitin glucuronyltransferase II; α-D-glucuronate:N-acetyl-β-D-galactosaminyl-(1?4)-β-D-glucuronosyl-proteoglycan 3-β-glucuronosyltransferase. Cat No: EXWM-2455. | |
| Native Flavobacterium heparinum Chondroitinase AC | Chondroitinase AC from Flavobacterium heparinum is an enzyme that cleaves sulfated and non-sulfated polysaccharide chains with (1-4) linkages between hexosamines and glucuronic acid residues, by an elimination mechanism. The resulting oligosaccharide products are mainly disaccharides with unsatuRated uronic acids. Chondroitinase AC specifically degrades chondroitin sulfates A and C, but not chondroitin sulfate B (dermatan sulfate). Applications: Chondroitinase ac from creative enzymes has been used for the large scale preparation of glycosaminoglycan (gag) fractions during the study of structural and sequence motifs in dermatan sulfate. Group: Enzymes. Synonyms: EC 4.2.2.5; 9047-57-8; chondroitin AC lyase; chondroitinase; chondroitin sulfate lyase; chondroitin AC eliminase; chondroitin AC lyase; chondroitinase AC; ChnAC. Enzyme Commission Number: EC 4.2.2.5. CAS No. 9047-57-8. ChnAC. Activity: 0.5-1.5 units/mg solid (using chondroitin sulfate A as substrate, also cleaves chondroitin sulfate C). Storage: -20°C. Form: lyophilized powder. Source: Flavobacterium heparinum. EC 4.2.2.5; 9047-57-8; chondroitin AC lyase; chondroitinase; chondroitin sulfate lyase; chondroitin AC eliminase; chondroitin AC lyase; chondroitinase AC; ChnAC. Cat No: NATE-0126. | |
| Native Flavobacterium heparinum Chondroitinase B | Chondroitinase B cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroitin B).The reaction yields oligosaccharide products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. Applications: Research reagent (glycobiology, preparation of oligosaccharide libraries from dermatan sulfate).determination of contents of chondrotin sulfates by hplc. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Mole weight: 55 kDa. Activity: >200 IU/mg (substrate: dermatan sulfate). Stability: 12 months frozen at -20°C in aqueous buffers containing sodium phosphate and sucrose 5%. Source: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Cat No: NATE-1950. | |
| Native Flavobacterium heparinum Chondroitinase C | Chondroitinase C acts upon chondroitin sulfate C, releasing unsatuRated 6-sulfated disaccharides. The enzyme also acts on hyaluronic acid, producing unsatuRated nonsulfated disaccharides. The enzyme is strongly inhibited by NaCl, Fe2+, Co2+ and phosphate ions. Group: Enzymes. Synonyms: EC 4.2.2.x,; 60184-91-0; Chondroitinase C; Chondroitin C lyase. Enzyme Commission Number: EC 4.2.2.x. CAS No. 60184-91-0. Chondroitinase C. Activity: > 200 units/mg solid. Storage: -20°C. Form: lyophilized powder. Source: Flavobacterium heparinum. EC 4.2.2.x,; 60184-91-0; Chondroitinase C; Chondroitin C lyase. Cat No: NATE-0132. | |
| Native Proteus vulgaris Chondroitinase ABC | Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl or (1-3)-α-L-iduronosyl linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate, and acts slowly on hyaluronate. The molecular weight is found to be approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is found to be 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid and tempeRature optimum is 37°C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activ...BC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Enzyme Commission Number: EC 4.2.2.4. CAS No. 9024-13-9. Chondroitinase ABC. Activity: 50-250 units/mg protein (using chondroitin sulfate C as substrate); 0.3-3 units/mg solid (using chondroitin sulfate C as substrate). Storage: -20°C. Form: lyophilized powder. Source: Proteus vulgaris. EC 4.2.2.4, chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Cat No: NATE-0131. | |
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