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| Product | Description | |
|---|---|---|
| Chrysophanol | analytical standard. Group: Natural compounds. |  |
| Chrysophanol | Chrysophanic acid (Chrysophanol) is a natural anthraquinone with anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid treatment in SNU-C5 cells inhibited EGF-induced phosphorylation of EGFR and suppressed activation of downstream signaling molecules, such as AKT, extracellular signal-regulated kinase (ERK) and the mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). Chrysophanic acid (80 and 120 μm) significantly blocked cell proliferation when combined with the mTOR inhibitor, rapamycin. These findings offer the first evidence of anticancer activity for chrysophanic acid via EGFR/mTOR mediated signaling transduction pathway. Chrysophanol is a natural compound found in the roots and rhizomes of Rheum palmatum L. It can be used in cosmetics material. Uses: Anti-inflammatory. Synonyms: 1,8-dihydroxy-3-methylanthracene-9,10-dione. Grade: ≥ 98 %. CAS No. 481-74-3. Molecular formula: C15H10O4. Mole weight: 254.24. |  |
| Chrysophanol | Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR / p70S6K. Uses: Scientific research. Group: Natural products. Alternative Names: Chrysophanic acid. CAS No. 481-74-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-13595. |  |
| Chrysophanol | Chrysophanol. Group: Biochemicals. Alternative Names: Chrysophanic acid; 1,8-Dihydroxy-3-methylanthraquinone. Grades: Plant Grade. CAS No. 481-74-3. Pack Sizes: 20mg. Molecular Formula: C15H10O4, Molecular Weight: 254.238. US Biological Life Sciences. |  Worldwide |
| Chrysophanol 1-O-glucoside | Chrysophanol 1-O-glucoside, an inherent component of diverse botanical species, boasts of paramount attention for its noteworthy anti-inflammatory and anti-tumor potentialities that have long been professed in traditional medicine. Its multifaceted pharmacological abilities have been under the researchers' radar, warranting potential deployment in treating metabolic maladies, liver afflictions, and obesity. Besides, this natural compound may stimulate the food and cosmetics industries with its remarkable antioxidant traits. Synonyms: 8-hydroxy-3-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione; Chrysophanol 1-glucoside. Grade: >98%. CAS No. 4839-60-5. Molecular formula: C21H20O9. Mole weight: 416.382. | |
| Chrysophanol 8-O-glucoside | Chrysophanol 8-O-glucoside, from the roots of Rumex acetosa , shows moderate elastase inhibition activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 13241-28-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2395. | |
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