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CID 2858522 CID 2858522. Group: Biochemicals. Grades: Purified. CAS No. 758679-97-9. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
CID 2858522 (Selectively Inhibits PKC-induced NF-kB Activation, 1-[3,5-Bis(1,1-dimethylethyl)-4-hyd roxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dime thyl-1H-benzimidazol-1-yl]ethanone) Selectively inhibits protein kinase C (PKC)-induced activation of the NF-kappaB pathway (IC50 < 0.1um for PMA-stimulated IL-8 production). Inhibits antigen receptor-stimulated NF-kappaB activation in chronic lymphocytic leukemia (CLL) B cells. Does not inhibit other NF-kappaB pathways, including that activated by tumor necrosis factor (TNF). Group: Biochemicals. Grades: Highly Purified. CAS No. 758679-97-9. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
CID-2858522 CID-2858522 selectively inhibits the NF-κB pathway induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways. Synonyms: CID2858522; CID-2858522; CID 2858522; ML029; ML-029; ML 029. Grades: >98%. CAS No. 758679-97-9. Molecular formula: C28H39N3O3. Mole weight: 465.63. BOC Sciences 10
1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]-ethanone 1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]-ethanone is a selective benzimidazole inhibitor of the antigen receptor-mediated NF-kB activation pathway. Group: Biochemicals. Alternative Names: CID 2858522. Grades: Highly Purified. CAS No. 758679-97-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C28H39N3O3, Molecular Weight: 465.63. US Biological Life Sciences. USBiological 3
Worldwide

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