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| Product | Description | |
|---|---|---|
| CID 5951923 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CID 5951923 | CID 5951923. Group: Biochemicals. Grades: Purified. CAS No. 749872-43-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CID 5951923 | CID 5951923 has been found to be a KLF-5 expression inhibitor and could exhibit selective activity against colon cancer cells. Synonyms: CID-5951923; CID 5951923; CID5951923; 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate. Grades: ≥97% by HPLC. CAS No. 749872-43-3. Molecular formula: C16H18N2O7S. Mole weight: 382.39. |  |
| KLF5 Inhibitor, CID 5951923 (2- ( (1, 1-Dioxidotetra hydrothiophen-3-yl, methyl)amino)-2-oxoethyl-(2E)-3-(3-nitrophenyl)prop-2-enoate) | A cell-permeable phenylpropenoate compound that inhibits the proliferation of colon cancer cell lines exhibiting high levels of KLF5 (IC50=1.6uM in DLD-1 cells). Downregulates the expression of early growth response protein 1 (EGR1), which modulates KLF5 expression at transcription level. Shown to activate the EGFR/ERK pathway by stimulating phosphorylation of EGFR-Tyr1068 and ERK1/2-Thr202/Tyr204. Also, up-regulates the phosphorylation of p38 MAPK-Thr180/Tyr182. Group: Biochemicals. Grades: Highly Purified. CAS No. 749872-43-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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