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| Product | Description | |
|---|---|---|
| Cilazapril | An ACE inhibitor. Hydrolyzed in vivo to the active diacid metabolite (Cilazaprilat). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Cilazapril | Cilazapril is a very potent and highly effective angiotensin-converting enzyme inhibitor (ACE inhibitor). It is used for the treatment of hypertension and congestive heart failure. lt is a monoethyl ester. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat by non-specific esterases. It is known that the diacid form is more potent. It has been listed. Uses: Cilazapri is used for the treatment of hypertension and congestive heart failure. Synonyms: Cilazapril; Ro 34-2848; Ro-34-2848; Ro34-2848. 7-[ (2-amino-2-carboxylatoethyl) thio]-2-[[ (2, 2-dimethylcyclopropyl) carbonyl]amino]hept-2-enoate; 6H-Pyridazino[1, 2-a][1, 2]diazepine-1-carboxylic acid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, (1S,9S)-;6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, [1S-[1α,9α(R*)]]-;Ro 31-2848;(1S,9S)-9-[(S)-1-Ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid; Inhibace; Vascace; Cilazaprilum; (4S, 7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1, 2, 3, 4, 7, 8, 9, 10-octahydropyridazino[1, 2-a]diazepine-4-carboxylic acid. Grades: >98%. CAS No. 88768-40-5. Molecular formula: C22H31N3O5. Mole weight: 417.50. |  |
| Cilazapril | Cilazapril. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88768-40-5. Molecular Formula: C22H31N3O5. Mole Weight: 417.5. Catalog: APB88768405. |  |
| Cilazaprilat | An ACE inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cilazaprilat | Cilazaprilat is the active metabolite of Cilazapril. It is an ACE inhibitor. Cilazaprilat shows antihypertensive activity. Uses: Antihypertensive agents. Synonyms: (1S,9S)-9-[[(1S)-1-Carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic Acid; Ro 31-3113. Grades: > 95%. CAS No. 90139-06-3. Molecular formula: C20H27N3O5. Mole weight: 389.45. | |
| Cilazapril EP Impurity A | Cilazapril EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106860-19-9. Molecular Formula: C26H39N3O5. Mole Weight: 473.61. Catalog: APB106860199. | |
| Cilazapril EP Impurity B | Cilazapril EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 90139-06-3. Molecular Formula: C20H27N3O5. Mole Weight: 389.45. Catalog: APB90139063. | |
| Cilazapril EP Impurity C | Cilazapril EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H35N3O5. Mole Weight: 445.56. Catalog: APB07456. | |
| Cilazapril EP Impurity D | Cilazapril EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106928-09-0. Molecular Formula: C22H31N3O5. Mole Weight: 417.51. Catalog: APB106928090. | |
| Cilazapril Impurity 1 | Cilazapril Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124620-51-5. Molecular Formula: C17H25NO5. Mole Weight: 323.39. Catalog: APB124620515. | |
| Cilazapril monohydrate | Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-2848 monohydrate. CAS No. 92077-78-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0043A. |  |
| Cilazapril Monohydrate | Cilazapril is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: CILAZAPRIL MONOHYDRATE;6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, 9-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)octahydro-10-oxo-, monohydrate, (1S-(1alpha,9alpha(R*)))-; 6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, octahydro-9-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-10-oxo-, hydrate, (1S-(1-alpha,9-alpha(R*)))-; MS-27800; D01069; Q27252108; (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate; (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid--water (1/1); 6H-PYRIDAZINO(1,2-A)(1,2)DIAZEPINE-1-CARBOXYLIC ACID, 9-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)OCTAHYDRO-10-OXO-, MONOHYDRATE, (1S-(1.ALPHA.,9.ALPHA.A(R*)))-. Grades: >98%. CAS No. 92077-78-6. Molecular formula: C22H33N3O6. Mole weight: 435.51. | |
| Cilazapril N-Nitroso Impurity | Cilazapril N-Nitroso Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1053740-92-3. Molecular Formula: C22H30N4O6. Mole Weight: 446.5. Catalog: APB1053740923. | |
| Cilazapril Piperazine Impurity | Cilazapril Piperazine Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 816454-25-8. Molecular Formula: C21H22N2O6. Mole Weight: 398.41. Catalog: APB816454258. | |
| Carboxylesterase 2 from Human, Recombinant | Member of a serine esterase family that hydrolyze ester and amide bonds. Carboxylesterase 2 is an endoplasmic reticulum-bound hydrolase that plays a critical role in xenobiotic detoxification and activation for ester-containing therapeutics. Carboxylesterase 2 is also involved in the detoxification of drugs such as heroin and cocaine. This enzyme is thought to play a role in lipid metabolism. Human carboxylesterase 2 (hCE-2) recognizes a substrate with a large alcohol group and small acyl group. Its substrate specificity may be restricted by a capability of acyl-hCE-2 conjugate formation due to the presence of conformational interference in the active site pocket. Carboxylesterases catalyze the biotransformation of several ester-containing drugs and prodrugs such as angiotensin-converting enzyme inhibitor (temocarpil, cilazapril), anti-tumor drugs (capecitabin) and narcotics. Group: Enzymes. Synonyms: EC 3.1.1.1; Carboxylesterase 2; CES2; CES2A1; CE-2; . Enzyme Commission Number: EC 3.1.1.1. CAS No. 9016-18-6. Purity: >95% (SDS-PAGE). Esterase. Mole weight: ~60 kDa. Activity: >30,000 (pmol/min/μg). Storage: Store at -70°C. Form: Supplied as a solution containing sodium chloride, sodium acetate, and 20% glycerol. Source: Mouse NSO cells. Species: Human. EC 3.1.1.1; Carboxylesterase 2; CES2; CES2A1; CE-2; PCE-2; iCE. Cat No: NATE-0812. |  |
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