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| Product | Description | |
|---|---|---|
| Cilomilast | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Cilomilast | Cilomilast. Group: Biochemicals. Alternative Names: cis-4-Cyano-4- [3- (cyclopentyloxy) -4-methoxyphenyl] cyclohexanecarboxylic acid; cis-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-4-cyanocyclohexane-1-carboxylic acid; Ariflo. Grades: Highly Purified. CAS No. 153259-65-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H25NO4. US Biological Life Sciences. |  Worldwide |
| Cilomilast | Cilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4) , with IC 50 s of ~100 and 120 nM for LPDE4 and HPDE4, respectively. Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 ( IC 50=74, 65, >100, and 83 μM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-207499. CAS No. 153259-65-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10790. |  |
| Cilomilast | Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; used in treatment of chronic obstructive pulmonary disease. Uses: Phosphodiesterase 4 inhibitors. Synonyms: SB 207499; SB-207499; SB207499. Cilomilast; Ariflo. Grades: 0.98. CAS No. 153259-65-5. Molecular formula: C20H25NO4. Mole weight: 343.423. |  |
| CI-1044 | CI-1044, a selective PDE4 inhibitor, inhibits in vitro LPS-induced TNF-alpha release in whole blood from COPD patients better than rolipram and cilomilast and suggested that it could be a useful anti-inflammatory therapy in COPD. Synonyms: CI-1044; CI 1044; CI1044; UNII-O4T475XIIY; PD-189659; PD 189659; PD189659; N-(9-amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro(1,4)diazepino(6,7,1-hi)indol-3-yl)nicotinamide. Grades: >98%. CAS No. 197894-84-1. Molecular formula: C23H19N5O2. Mole weight: 397.43. | |
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