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Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.1 The oxidation of coelenterazine to coelenteramide is accompanied by emission of blue light (emission maximum, 460-470 nm). Luciferase-mediated oxidation of coelenterazine or a derivative is used as an energy donor, typically to a form of green or yellow fluorescent protein, in bioluminescent resonance energy transfer studies.2,3 Alternatively, the calcium-mediated release of coelenterazine from aequorin, followed by non-enzymatic oxidation of this compound, results in bioluminescence. As light emission depends on both calcium and cellular redox status, this reaction is used to non-fluorescently detect changes in calcium level and redox status.4,5. Group: Biochemicals. Alternative Names: 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one; CLZN; Preluciferin; Luciferin; 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one. Grades: Highly Purified. CAS No. 55779-48-1. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 423.46. US Biological Life Sciences.
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Coelenterazine
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 55779-48-1. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18743.
Coelenterazine 400a
Coelenterazine 400 a is a chromophore that produces the chemiluminescence displayed by the Aequorin protein in the presence of Ca2+. Group: Biochemicals. Alternative Names: 6-Phenyl-2, 8-bis (phenylmethyl) imidazo[1, 2-a]pyrazin-3 (7H) -one; Bisdeoxycoelenterazine ; Coelenterazine HH; DeepBlueC; Dideoxycoelenterazine; BlueSyn C; 2,8-Dibenzyl-6-phenyl-imidazo[1,2a]pyrazin-3-(7H)-one. Grades: Highly Purified. CAS No. 70217-82-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??N?O, Molecular Weight: 391.46. US Biological Life Sciences.
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Coelenterazine e
Coelenterazine e. Group: Biochemicals. Grades: Highly Purified. CAS No. 114496-02-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C28H23N3O3, Molecular Weight: 449.5. US Biological Life Sciences.
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Coelenterazine F
Coelenterazine F. Group: Biochemicals. Alternative Names: Coelenterazine-Fluoride; 8-benzyl-2- (4-fluorobenzyl) -6- (4-hydroxyphenyl) imidazo[1, 2- a]pyrazin-3(7H)-one. Grades: Highly Purified. CAS No. 123437-16-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C26H20FN3O2. US Biological Life Sciences.
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Coelenterazine h
Coelenterazine h (2-Deoxycoelenterazine), a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h is more sensitive to Ca 2+ , thus providing a valuable tool for measuring small changes in Ca 2+ concentrations [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Deoxycoelenterazine; CLZN-h. CAS No. 50909-86-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1024.
Coelenterazine h
Coelenterazine h. Group: Biochemicals. Alternative Names: 2-Deoxycoelenterazine; 2, 8-dibenzyl-6- (4-hydroxyphenyl) imidazo[1, 2-a]pyrazin-3 (7H) -one. Grades: Highly Purified. CAS No. 50909-86-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C26H21N3O2. US Biological Life Sciences.
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Coelenterazine h
solid. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 50909-86-9. Pack Sizes: 50μG. Mole Weight: 407.46. Catalog: AP50909869.
Coelenterazine, native
solid. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 55779-48-1. Pack Sizes: 50μG. Mole Weight: 423.46. Catalog: AP55779481. Assay: ≥95% (TLC).
Coelenterazine v
Coelenterazine v. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. US Biological Life Sciences.
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Oplophorus-luciferin 2-monooxygenase
The luciferase from the deep sea shrimp Oplophorus gracilirostris is a complex composed of more than one protein. The enzyme's specificity is quite broad, with both coelenterazine and bisdeoxycoelenterazine being good substrates. Group: Enzymes. Synonyms: Oplophorus luciferase. Enzyme Commission Number: EC 1.13.12.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0606; Oplophorus-luciferin 2-monooxygenase; EC 1.13.12.13; Oplophorus luciferase. Cat No: EXWM-0606.
pyCTZ
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Pyridyl CTZ. CAS No. 2125486-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135367.
QTZ
QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2883232-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-47176.
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