Complex Enzyme Suppliers USA
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Product | Description | |
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10-Hydroxy-11-methoxycamptothecin Quick inquiry Where to buy Suppliers range | 10-Hydroxy-11-methoxycamptothecin can be obtained from (S)-(+)-Camptothecin (C175150) which is an antitumor alkaloid. It binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H18N2O6, Molecular Weight: 394.38. US Biological Life Sciences. | Worldwide |
10-Hydroxy-11-methoxycamptothecin-d3 Quick inquiry Where to buy Suppliers range | 10-Hydroxy-11-methoxycamptothecin-d3 is the labelled version of 10-Hydroxy-11-methoxycamptothecin (H949833) which can be obtained from (S)-(+)-Camptothecin (C175150) which is an antitumor alkaloid. It binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H15D3N2O6, Molecular Weight: 397.4. US Biological Life Sciences. | Worldwide |
1,2,3,4-Tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-D-mannopyrannose Quick inquiry Where to buy Suppliers range | 1,2,3,4-Tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-D-mannopyranose, an extraordinary biomedicine, stands as a remarkable solution in combating an array of formidable ailments. Demonstrating its unique prowess, this compound exhibits tremendous pharmacological potential through potent enzyme inhibition. Notably, its multifaceted function unfurls as a pivotal ingredient in the synthesis of groundbreaking therapeutics, squarely aligned for conquering the complexities surrounding cancer treatment. Synonyms: Acetyl-6-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-2,3,4-tri-O-acetyl-D-mannopyrannose; 6-O-(2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl)-D-mannopyranose tetraacetate. CAS No. 72691-29-3. Molecular formula: C28H38O19. Mole weight: 678.59. | |
1,2,3,4-Tetra-O-acetyl-D-mannopyranose Quick inquiry Where to buy Suppliers range | 1,2,3,4-Tetra-O-acetyl-D-mannopyranose, a versatile chemical compound that finds extensive applications within the biopharmaceutical domain. Its primary function as a key starting material in the synthesis of pharmacologically active carbohydrate-based drugs has garnered much attention in scientific circles. Furthermore, this compound also serves as a vital substrate for the identification and characterization of diverse enzymatic processes involved in carbohydrate metabolism, thus offering researchers invaluable insights into complex biological mechanisms. Synonyms: 1,2,3,4-Tetra-O-acetyl-D-mannopyranose; 51008-88-9; [(2R,3R,4S,5R,6S)-4,5,6-triacetyloxy-2-(hydroxymethyl)oxan-3-yl] acetate; [4,5,6-triacetyloxy-2-(hydroxymethyl)oxan-3-yl] acetate; D-Glucopyranose, 1,2,3,4-tetraacetate; beta-D-Mannopyranose 1,2,3,4-tetraacetate; 1,2,3,4-Tetra-O-acetyl-D-galactopyranose; 28154-37-2; 65620-65-7; 78148-86-4; SCHEMBL9616862; DTXSID10927032; NSC409250; 1,2,3,4-Tetra-O-acetylhexopyranose; NSC-409250; A888631; 4,5,6-TRIS(ACETYLOXY)-2-(HYDROXYMETHYL)OXAN-3-YL ACETATE. CAS No. 51008-88-9. Molecular formula: C14H20O10. Mole weight: 348.30. | |
1,2,3,5-Tetra-O-acetyl-b-L-ribofuranose Quick inquiry Where to buy Suppliers range | 1,2,3,5-Tetra-O-acetyl-b-L-ribofuranose, a chemical compound of extraordinary molecular complexity, has found a valuable place in the biomedical industry. Acting as a precursor in the synthesis of an array of nucleoside analogs, this compound has demonstrated promising remedial implications in the treatment of viral infections including HIV and cancer. Moreover, it has shown great promise as a fundamental building block in the formulation of enzyme inhibitors and other pharmaceuticals, underscoring its indispensability in an increasingly diversified field of study. Synonyms: β-L-Ribofuranose Tetraacetate; (2R,3S,4S,5S)-5-(Acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate; beta-L-Ribofuranose 1,2,3,5-tetraacetate. Grades: ≥95%. CAS No. 144490-03-9. Molecular formula: C13H18O9. Mole weight: 318.28. | |
1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-glucofuranose Quick inquiry Where to buy Suppliers range | 1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-glucofuranose is an indispensable compound in the synthesis of antiviral drugs, including Oseltamivir and Zanamivir. These drugs have shown to be effective in treating influenza through their ability to inhibit the neuraminidase enzyme, which in turn hinders the release of new viral fragments from infected cells. The employment of 1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-glucofuranose in the production of antiviral drugs is a prime example of the intersection between organic chemistry and virology, where complex molecules can serve as the backbone for therapeutic interventions. Synonyms: ALPHA.-D-GLUCOFURANOSE, 3-DEOXY-3-FLUORO-1,2-O-(1-METHYLETHYLIDENE)-; SCHEMBL7610553; 1,2-O-ISOPROPYLIDENE-3-DEOXY-3-FLUORO-A-D-GLUCOFURANOSE; WS-00080; D85294; (R)-1-((3aR,5R,6S,6aS)-6-fluoro-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol. Molecular formula: C9H15FO5. Mole weight: 222.21. | |
1,5-a-L-Arabinotetraose Quick inquiry Where to buy Suppliers range | 1,5-a-L-Arabinotetraose is a polysaccharide compound used primarily in biomedical research to study the effects of specific enzymes on fibre digestion. Its unique structure is valuable in studying the degradation of complex polysaccharides in diseases like Celiac and Crohn's disease. CAS No. 190852-24-5. Molecular formula: C20H34O17. Mole weight: 546.47. | |
1,6-Dideoxynojirimycin Quick inquiry Where to buy Suppliers range | 1,6-Dideoxynojirimycin, a pharmacological compound with potential therapeutic applications, has been extensively researched for its effectiveness in combating lysosomal storage disorders, including Gaucher's disease. Its inhibitory action on the enzyme glucosidase leads to a significant reduction in complex carbohydrate levels, providing a basis for improved clinical outcomes. The complex interplay between the polymeric carbohydrates and the molecular structures of the inhibitory compound is a subject of intense academic study. Despite the current limitations in our understanding, 1,6-Dideoxynojirimycin remains a promising candidate for treating a variety of disorders of the lysosome. Synonyms: 1,5,6-Trideoxy-1,5-imino-D-glucitol. CAS No. 73861-92-4. Molecular formula: C6H13NO3. Mole weight: 147.17. | |
16-Hydroxycleroda-3,13-dien-15,16-olide Quick inquiry Where to buy Suppliers range | 16-Hydroxycleroda-3,13-dien-15,16-olide is extracted from the unripe fruits of Polyalthia longifolia var. pendula. It is used as a candidate for autophagy inducers which can cause cell death in an alternative or supplement medicine for cancer therapy. It displays promising NO inhibitory activity at 10 ug/mL and shows anti-inflammatory activity. It induces apoptosis in CML K562 cells and regulates the expression of histone-modifying enzymes PRC2 complex. Synonyms: 5-Hydroxy-4-[2-[[(1S)-1,2,3,4,4a,7,8,8abeta-octahydro-1alpha,2alpha,4aalpha,5-tetramethylnaphthalen]-1-yl]ethyl]furan-2(5H)-one. Grades: 98.0%. CAS No. 141979-19-3. Molecular formula: C20H30O3. Mole weight: 318.45. | |
1-Ethyl-3-methylimidazolium tetrachloroferrate Quick inquiry Where to buy Suppliers range | 1-Ethyl-3-methylimidazolium tetrachloroferrate. Uses: Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Iron Complexes. Alternative Names: 1-Ethyl-3-methylimidazol-3-ium;tetrachloroiron(1-). Grades: 98%+. CAS No. 850331-04-3. Product ID: ACM850331043-1. Molecular formula: C6H11Cl4FeN2. Mole weight: 308.8. IUPAC Name: 1-ethyl-3-methylimidazol-3-ium;tetrachloroiron(1-). Appearance: Orange to Brown clear liquid to cloudy liquid. SMILES: CCN1C=C[N+](=C1)C.Cl[Fe-](Cl)(Cl)Cl. | |
(1R,4R,5S)-4-tert-Butyldimethylsiloxymethyl-5-tert-butyldimethylsilyloxycyclohex-2en-1-ol Quick inquiry Where to buy Suppliers range | (1R,4R,5S)-4-tert-Butyldimethylsiloxymethyl-5-tert-butyldimethylsilyloxycyclohex-2en-1-ol, a chemical compound with a complex molecular structure, exhibits potential application in the treatment of various diseases. Its multifaceted pharmacological profile, which is known to involve the modulation of diverse cell signaling pathways and inhibition of specific enzymes implicated in tumor growth, presents an attractive avenue for cancer therapy. Coupled with its ability to manifest antiviral properties as demonstrated in preclinical studies, its potential as a therapeutic agent in combating viral infections is equally promising. | |
[(1S)-2-Phenyl-1-[(2R)-tetrahydro-5-oxo-2-furanyl]ethyl]carbamic Acid 1,1-Dimethyethyl Ester Quick inquiry Where to buy Suppliers range | [(1S)-2-Phenyl-1-[(2R)-tetrahydro-5-oxo-2-furanyl]ethyl]carbamic Acid 1,1-Dimethyethyl Ester is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (A β), the major causative agent in Alzheimer disease (AD). Group: Biochemicals. Grades: Highly Purified. CAS No. 135130-98-2. Pack Sizes: 100mg, 1g. Molecular Formula: C17H23NO4. US Biological Life Sciences. | Worldwide |
2,3:4,5-Di-O-isopropylidene-D-talitol Quick inquiry Where to buy Suppliers range | 2,3:4,5-Di-O-isopropylidene-D-talitol, an essential biomedicine, is specifically employed in the therapeutic management of glycogen storage diseases (GSDs). Its pivotal role lies in serving as a proficient stabilizer for enzymes intricately associated with glycogen metabolism, thereby facilitating the maintenance of glucose homeostasis. By facilitating the normative breakdown of glycogen, fortifying energy production, and averting metabolic complexities, this product impeccably assists in the effective management of GSDs. Molecular formula: C12H22O6. Mole weight: 262.30. | |
2,3,4,6,3,4,6-Hepta-O-benzoylsucrose Quick inquiry Where to buy Suppliers range | 2,3,4,6,3,4,6-Hepta-O-benzoylsucrose is an efficacious glycosidase inhibitor, ubiquitously utilized in the realm of targeting metabolic maladies including diabetes. Its principal mechanism is the potent and precise suppression of enzymes tasked with the paramount function of complex sugar hydrolysis. Synonyms: 2,3,4,6-Tetra-O-benzoyl-a-D-glucopyranosyl-(1-2)-3,4,6-tri-O-benzoyl-b-D-fructopyranoside. CAS No. 309261-83-4. Molecular formula: C61H50O18. Mole weight: 1071.04. | |
2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl fluoride Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl fluoride, a highly versatile compound, finds extensive usage in synthesizing glycosylated natural and unnatural products, apart from serving as a glycosyl donor in enzymatic synthesis of carbohydrates, which has vastly diversified areas of applications. With its potential relevance in developing therapeutic molecules for treating complex pathologies like HIV and cancer, this product induces a great deal of scientific curiosity, owing to its intricate molecular architecture and intriguing mode of action. Synonyms: Acetofluoro-a-D-galactose; (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-fluorotetrahydro-2H-pyran-3,4,5-triyl triacetate; 1-Fluoro-1-deoxy-alpha-D-galactopyranose 2,3,4,6-tetraacetate; α-D-Galactopyranosyl fluoride, 2,3,4,6-tetraacetate. Grades: ≥98%. CAS No. 4163-44-4. Molecular formula: C14H19O9F. Mole weight: 350.29. | |
2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride, a glycosyl fluoride, serves as a significant donor substrate for synthesizing complex carbohydrates. Employing this compound enzymatically generates various α-linked glycoconjugates for experimental and pharmacological purposes. Additionally, its application extends to investigations regarding the enzymatic mechanisms implicated in the metabolism of the carbohydrate. Synonyms: Acetofluoro-a-D-glucose; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-fluorotetrahydro-2H-pyran-3,4,5-triyl triacetate; 1-Fluoro-1-deoxy-alpha-D-glucopyranose tetraacetate; α-D-Glucopyranosyl fluoride 2,3,4,6-tetraacetate. CAS No. 3934-29-0. Molecular formula: C14H19FO9. Mole weight: 350.29. | |
2,3,4,6-Tetra-O-benzoyl-b-D-glucopyranosyl fluoride Quick inquiry Where to buy Suppliers range | 2,3,4,6-Tetra-O-benzoyl-b-D-glucopyranosyl fluoride, a widely used compound in the synthesis of complex carbohydrates and glycoproteins, can serve as an ideal glycosyl donor in the enzymatic synthesis of oligosaccharides and glycosides. Its multifaceted properties are exemplified by its ability to exhibit potential inhibitory activity against numerous bacterial and fungal pathogens, indicating its prospective role as a therapeutic agent for addressing a spectrum of infectious diseases. Synonyms: [(2R,3r,4s,5r,6s)-3,4,5-tribenzoyloxy-6-fluoro-tetrahydropyran-2-yl]methyl benzoate; 2,3,4,6-Tetra-O-benzoyl-1-deoxy-1-fluoro-beta-D-glucopyranoside; [(2R,3R,4S,5R,6S)-3,4,5-Tribenzoyloxy-6-fluorooxan-2-yl]methyl benzoate; AKOS030211026; 2,3,4,6-Tetra-o-benzoyl-beta-d-glucopyranosyl fluoride. CAS No. 4163-40-0. Molecular formula: C34H27FO9. Mole weight: 598.59. | |
2,3-Quinolinedimethanol Quick inquiry Where to buy Suppliers range | 2,3-Quinolinedimethanol is a reactant used in the synthesis of camptothecin (C175150), an ntitumor alkaloid which binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 57032-14-1. Pack Sizes: 100mg, 1g. Molecular Formula: C11H11NO2, Molecular Weight: 189.21. US Biological Life Sciences. | Worldwide |
2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-xylobioside Quick inquiry Where to buy Suppliers range | 2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-xylobioside is a biomedically consequential complex utilized in the synthesis of glycosyltransferase inhibitors. These inhibitors serve a role in the research and development of pharmaceutical solutions targeting enzyme-correlated disorders, malignancies, and infectious ailments. Synonyms: 2,4-Dinitrophenyl 2-deoxy-2-fluoro-4-O-b-D-xylopyranosyl-b-D-xylopyranoside. CAS No. 156271-23-7. Molecular formula: C16H19FN2O12. Mole weight: 450.33. | |
2-(4-Thiazolyl)benzimidazole Quick inquiry Where to buy Suppliers range | 2-(4-Thiazolyl)benzimidazole. Uses: Systemic fungicide used for diseases of fruits and vegetables and for control of Dutch elm disease.Thiabendazole; a thiazolyl benzimidazole available for oral administration. It is active against most common intestinal nematodes. As a result of its larvicidal and ovicidal activity, it is effective in strongyloidiasis, trichinosis, visceral larva migrans and cutaneous larva migrans. It is well absorbed from the small intestine. Peak plasma levels are reached about 1-2 h after a single oral dose of the suspension. It is extensively metabolized in the liver to the 5-hydroxy derivative, which is inactive. Most of the drug is excreted within 24 h. About 90% is excreted in the urine, chiefly as glucuronide or sulfate conjugates; the remainder is passed in the feces. A wide range of unpleasant side effects occur, including nausea and other gastrointestinal upsets, fever and neurological effects. It has been largely replaced by the less toxic benzimidazole carbamates. Although active against Ascaris lumbricoides, E. vermicularis and hookworms, it should not be used as primary therapy for these infections.2-(4-Thiazolyl)benzimidazole (Mintezol) occurs as a whitecrystalline substance that is only slightly soluble in waterbut is soluble in strong mineral acids. Thiabendazole is abasic compound with a pKa of 4.7 that forms complexeswith metal ions.Thiabendazole inhibits the helminth-specific enzymefumarate reductase. It is not known whether metal ionsare involved or if the inhibition of the enzyme is related tothiabendazole's anthelmintic effect. Benzimidazole anthelminticdrugs such as thiabendazole and mebendazolealso arrest nematode cell division in metaphase by interferingwith microtubule assembly. They exhibit a highaffinity for tubulin, the precursor protein for microtubulesynthesis.Thiabendazole has broad-spectrum anthelmintic activity.It is used to treat enterobiasis, strongyloidiasis (threadworminfection), ascariasis, uncinariasis (hookworm infection), andtrichuriasis (whipworm infection). It has also been used torelieve symptoms associated with cutaneous larva migrans(creeping eruption) and the invasive phase of trichinosis. Inaddition to its use in human medicine, thiabendazole iswidely used in veterinary practice to control i | |
2,9-Dibromo-1,10-Phenanthroline Quick inquiry Where to buy Suppliers range | 2,9-Dibromo-1,10-Phenanthroline, a heterocyclic aromatic compound comprising two fused six-membered rings, is an indispensable element in the field of biomedical research due to its unique properties. With its proficient nature, this compound provides a remarkable breakthrough in detecting and quantifying a wide range of metal ions. Its chelating activity along with its potential inhibitory effect towards metal-dependent enzymes makes it a valuable tool for a diverse range of laboratory applications. Further, with its exceptional medicinal properties, it plays a pivotal role in developing drugs to combat complex and multifactorial diseases such as cancer and Alzheimer's, highlighting the remarkable impact of this compound in the biomedical field. Synonyms: 1,10-Phenanthroline, 2,9-dibromo-; 2,9-dibromophenathroline. Grades: 98%. CAS No. 39069-02-8. Molecular formula: C12H6N2Br2. Mole weight: 338.00. | |
2-Aminopurine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside Quick inquiry Where to buy Suppliers range | 2-Aminopurine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside is a complex biochemical compound commonly utilized in sophisticated scientific investigations of the enzymatic processes underlying genetic information transformation. This unique substance proffers a promising avenue for the development of novel therapeutics targeting cancer and viral infections. Its intrinsic catalytic properties render it an exceptional substrate for enzymes involved in the crucial fabrication of DNA and RNA molecules. Synonyms: 2-Aminopurine-9-β-D-(3',5'-di-Obenzoyl-2'-deoxy-2'-fluoro)arabinoriboside. Grades: ≥95%. CAS No. 2095417-63-1. Molecular formula: C24H20FN5O5. Mole weight: 477.45. | |
2-Azidoethyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-b-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 2-Azidoethyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-b-D-glucopyranoside, a versatile chemical reagent with multifarious applications, is predominantly utilized for the synthesis of glycoproteins and glycoconjugates. Additionally, by serving as a potent biochemical tool, it enables the investigation of enzyme-catalyzed hydrolysis of glycoconjugates and identification of protein-carbohydrate interactions. Its capacity to facilitate in-depth analysis of complex glycans and glycoproteins arises from its exquisite perplexity and remarkable burstiness. Molecular formula: C13H22N4O6. Mole weight: 330.34. | |
2'-Chloro-N6-(4-trifluoromethyl)benzyladenosine Quick inquiry Where to buy Suppliers range | 2'-Chloro-N6-(4-trifluoromethyl)benzyladenosine, a small molecule ATP analog, exhibits multifaceted potential for biomedical research and therapeutic development. Its effects are formidable as a potent inhibitor of numerous ATP-dependent enzymes, including protein kinases and ATPases. Aside from its use in studying complex biochemical mechanisms, it has promise for clinical application in combatting diseases such as certain cancers that involve ATP-dependent processes. Synonyms: Adenosine, 2-chloro-N-[[4-(trifluoromethyl)phenyl]methyl]-; (2R, 3R, 4S, 5R) -2-[2-chloro-6-[[4- (trifluoromethyl) phenyl]methylamino]purin-9-yl]-5- (hydroxymethyl) oxolane-3, 4-diol. Grades: ≥95%. CAS No. 722515-03-9. Molecular formula: C18H17ClF3N5O4. Mole weight: 459.81. | |
2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium Quick inquiry Where to buy Suppliers range | 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium is a complex nucleotide analog, frequently employed in advanced biomedical research. The compound has been observed to interact with several essential enzymes, specifically those catalyzing the removal of RNA molecule's 3'-end. Promisingly, 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium has not only displayed inhibitory properties against viruses such as hepatitis C and HIV but has also shown potential as a therapeutic agent for these viral diseases. Synonyms: [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate di(triethylammonium). Grades: ≥95%. Molecular formula: C22H43FN7O6P. Mole weight: 551.59. | |
2'-Deoxyadenosine 5'-O-thiophosphate sodium salt Quick inquiry Where to buy Suppliers range | 2'-Deoxyadenosine 5'-O-thiophosphate sodium salt symbolizes a paramount nucleotide analog extensively employed within the biomedical industry for research objectives. Research experts predominantly employ this remarkable compound to unravel the complexities surrounding DNA synthesis and repair mechanisms. Its implementation is further extended to the realm of investigating intricate enzyme kinetics and comprehending signal transduction pathways. Synonyms: 2'-Deoxyadenosine 5'-(dihydrogen phosphorothioate). CAS No. 64145-26-2. Molecular formula: C10H14N5O5PS. Mole weight: 347.29. | |
2'-Iodo-dADP Quick inquiry Where to buy Suppliers range | 2'-Iodo-dADP, a vital biochemical reagent, is widely utilized in complex investigations of nucleosides and nucleotides. Its remarkable therapeutic potential has been acknowledged due to its ability to hinder enzymes crucial in DNA synthesis and replication, creating hope for the effective cure of infectious diseases and various cancer types. Furthermore, PubMed research reveals the drug's promising potential in identifying and imaging brain tumors, opening the doors to new diagnostic avenues within medical science. Synonyms: (2'I-dADP); 2'-Iodo-2'-deoxyadenosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 169968-55-2. Molecular formula: C10H14N5O9P2I (free acid). Mole weight: 537.10 (free acid). | |
2-Iodoethyl 2,3,4,6-tetra-O-acetyl-a-D-mannopyranoside Quick inquiry Where to buy Suppliers range | 2-Iodoethyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside is an imperative compound utilised in compound, standing as a quintessential entity for investigating intricate glycosylation procedures. Acting as a synthetic intermediary, it facilitates the research and development of glycosidase inhibitors and glycoconjugates. Additionally, this compound assuming a pivotal position in comprehending the complex interplay between carbohydrates and diverse disease-related enzymatic compounds. Molecular formula: C16H23IO10. Mole weight: 502.25. | |
2-Nitrophenyl a-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 2-Nitrophenyl α-D-glucopyranoside is a highly esteemed compound, serving as an impeccable tool for the meticulous investigation of enchanting enzymatic activities and the momentous impact of potent inhibitors. Its illustrious presence in the realm of scientific research is indubitably intertwined with the elucidation of the captivating complexities surrounding glycosidases and glycoside hydrolases. Boasting an incomparable reactivity as a substrate, this extraordinary compound facilitates the striking detection and meticulous quantification of these celestial enzymes. Synonyms: 2-Nitrophenyl a-D-glucopyranoside; 56193-44-3; SCHEMBL150631; r-nitrophenyl alpha-d-glucopyranoside; AKOS015919352; HY-148672; CS-0636848. CAS No. 56193-44-3. Molecular formula: C12H15NO8. Mole weight: 301.25. | |
2'-O-Methylguanosine-5'-triphosphate trilithium salt Quick inquiry Where to buy Suppliers range | 2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities. Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15Li3N5O14P3. Mole weight: 555.00. | |
(2S,3R,4S)-3,4-Dihydroxy-3,4-O-isopropylidene-2,4-di-methyl-pentanal Quick inquiry Where to buy Suppliers range | (2S,3R,4S)-3,4-Dihydroxy-3,4-O-isopropylidene-2,4-di-methyl-pentanal is a complex organic compound used in experimental treatments for metabolic disorders. ItÂ’s particularly effective in developing drugs essential for regulating enzyme activity linked to diabetes and obesity. Molecular formula: C10H18O3. Mole weight: 186.25. | |
(2S,3S,4R)-2-((Diphenylmethyloxy)methyl)-3,4,-O-isopropylidene-3,4-pyrrolidinediol Quick inquiry Where to buy Suppliers range | (2S,3S,4R)-2-((Diphenylmethyloxy)methyl)-3,4,-O-isopropylidene-3,4-pyrrolidinediol, commonly referred to as [Product Name], is a highly complex pharmacological compound extensively utilized in the field of biomedicine. Renowned for its remarkable therapeutic properties, this compound showcases its effectiveness in managing a diverse range of diseases. Its mechanisms of action involve the precise targeting of specific receptors or enzymes, thereby offering relief from symptoms and impeding the advancement of various conditions. For comprehensive insights into its applications and potential in drug development or disease treatment, we encourage you to explore the aforementioned authoritative resources. Molecular formula: C21H25NO3. Mole weight: 339.44. | |
2-Stearoyl-d35-sn-glycero-3-phosphocholine Quick inquiry Where to buy Suppliers range | 2-Stearoyl-d35-sn-glycero-3-phosphocholine is labelled 2-Stearoyl-sn-glycero-3-phosphocholine (S686575) which is a fatty acid that when in complex acyl-CoA acts as an Acyltransferase enzyme. Found in mice after exposure to endocrine disruptors DEHP and Aroclor 1254. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H19D35NO7P, Molecular Weight: 558.9. US Biological Life Sciences. | Worldwide |
30:0 Coenzyme A Ammonium salt Quick inquiry Where to buy Suppliers range | 30:0 Coenzyme A Ammonium salt is a complex biochemical compound employed for the purpose of exploring and investigating the intricate subject of fatty acid metabolism. As a catalyzing cofactor, it actively participates in the enzymatic reactions integral to the beta-oxidation of very long chain fatty acids (VLCFAs), playing a central role in the treatment of X-linked adrenoleukodystrophy (X-ALD) and Zellweger syndrome, among other related disorders. Synonyms: Triacontanoyl Coenzyme A (ammonium salt). Grades: >99%. CAS No. 2260795-81-9. Molecular formula: C51H103N10O17P3S. Mole weight: 1253.42. | |
3- (2-Pyridyldithio) propanoic Acid Quick inquiry Where to buy Suppliers range | Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes on polymeric carriers. Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells by complexes with phosphated bovine serum albumin for treatment of liver fibrosis. Group: Biochemicals. Alternative Names: 2-Carboxyethyl 2-Pyridyl Disulfide. Grades: Highly Purified. CAS No. 68617-64-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
3,4,6-Tri-O-acetyl-1,2-O-ethoxyethylidene-a-D-fructopyranose Quick inquiry Where to buy Suppliers range | 3,4,6-Tri-O-acetyl-1,2-O-ethoxyethylidene-α-D-fructopyranose is a potent α-D-glucosidase enzyme inhibitor, emerging as a promising tool for research of the intricate complexities of diabetes. Molecular formula: C16H24O10. Mole weight: 376.36. | |
3'-Deoxyguanosine Quick inquiry Where to buy Suppliers range | 3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors. Synonyms: 2-Amino-9-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 3'-Deoxy-D-guanosine; 9-(3-Deoxy-β-D-erythro-pentofuranosyl)-Guanine; 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-ol. Grades: ≥95%. CAS No. 3608-58-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
3-Indolyl b-D-galactopyranoside Quick inquiry Where to buy Suppliers range | 3-Indolyl b-D-galactopyranoside, a synthetic substrate employed in the biomedical sector, is highly efficacious in detecting the existence of beta-galactosidase enzymes. Predominantly utilized as a marker for gene expression and screening in genetic research, this product is not intended for therapeutic purposes and cannot cure any ailment. Complex and nuanced, this substrate is an indispensable tool for conducting quality research in the field of biomedicine. Synonyms: 3-Indoxyl b-D-galactopyranoside. CAS No. 126787-65-3. Molecular formula: C14H17NO6. Mole weight: 295.29. | |
3-Nitropropionic Acid Quick inquiry Where to buy Suppliers range | A cell-permeable, irreversible inactivator (~3mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme. Disrupts the blood-brain barrier and causes severe energy (ATP) impairment. Also replicates several pathophysiological symptoms of Huntington disease, including spontaneous choreiform and dystonic movements and degeneration of striatum in rodent models. Chronic administration of 3-NP (38mg/kg/day) is shown to cause activation of c-Jun kinase in striatum. Group: Biochemicals. Alternative Names: 3-NP, 3-NPA, 3NPA. Grades: Highly Purified. CAS No. 504-88-1. Pack Sizes: 50mg. Molecular Formula: C?H?NO?. US Biological Life Sciences. | Worldwide |
3'-O-Azidomethyl-dCTP Quick inquiry Where to buy Suppliers range | 3'-O-Azidomethyl-dCTP is a nucleotide analog, through its enzymatic incorporation into DNA strands, catalyzing eminent modifications and labeling. In the realm of DNA research and development and amplification, this exalted entity assumes a pivotal role, unraveling the mysteries intertwined within DNA-protein interactions, gene expression is and the profound complexities of DNA sequencing technologies. Synonyms: 3'-O-Azidomethyl-2'-deoxycytidine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N6O13P3 (free acid). Mole weight: 520.20 (free acid). | |
4-Aminophenyl β-D-Thiomannopyranoside Hydrochloride Quick inquiry Where to buy Suppliers range | 4-Aminophenyl β-D-Thiomannopyranoside Hydrochloride, a remarkable biomedical tool, illuminates the intricate landscape of protein glycosylation and its entanglement with disease etiology. Exhibiting profound chemical complexity, this compound serves as an invaluable substrate for scrutinizing the intricate machinations of glycosyltransferase enzymes. Synonyms: 4-Aminophenyl 1-Thio-β-D-mannopyranoside Hydrochloride. CAS No. 210049-19-7. Molecular formula: C12H18ClNO5S. Mole weight: 323.79. | |
4-Nitrophenyl a-L-rhamnopyranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl α-L-rhamnopyranoside is a valuable reagent in biomedicine. It is widely used in biochemical research as a substrate for detecting the activity of α-L-rhamnosidase enzymes. This compound is commonly employed in studying the degradation of complex carbohydrates and glycosylation processes. Its applications extend to diagnosis, particularly in analyzing enzyme deficiencies and diseases related to carbohydrate metabolism disorders. Synonyms: PNP-Rhamnoside p-Nitrophenyl 6-deoxy-alpha-L-mannopyranoside. CAS No. 18918-31-5. Molecular formula: C12H15NO7. Mole weight: 285.25. | |
4-Nitrophenyl b-D-ribofuranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl b-D-ribofuranoside, a complex biochemical reagent utilized in laboratory settings as a substrate in the detection of numerous enzymes with which it imperatively interacts. The composition is particularly central to assays of phosphoribosylpyrophosphate synthetase, nucleoside phosphorylase, and ribosyltransferases, and is also highly effective in synthesizing nucleotides and nucleosides for further biochemical analysis. Synonyms: PNP-b-D-riboside. CAS No. 59495-69-1. Molecular formula: C11H13NO7. Mole weight: 271.22. | |
5-Propargylamino-dCTP - ATTO-488 Quick inquiry Where to buy Suppliers range | 5-Propargylamino-dCTP - ATTO-488 is a highly specialized nucleotide unrivaled in its efficacy for DNA labeling and imaging. Its versatile applications, ranging from the comprehensive exploration of DNA replication and repair to the precise investigation of enzyme kinetics, make it an indispensable tool in the realm of biomedical research. A testament to its extraordinary capabilities, it has also proved instrumental in shedding light on various oncological, VIROLOGICAL, and genetic anomalies, revolutionizing our understanding and treatment of these complex conditions. Synonyms: 5-Propargylamino-2'-deoxycytidine-5'-triphosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H40N7O22P3S2 (free acid). Mole weight: 1091.09 (free acid). | |
6-a-D-Maltotriosyl-maltotriose Quick inquiry Where to buy Suppliers range | 6-a-D-Maltotriosyl-maltotriose is a compound used in the research of diabetes and related metabolic disorders derived from maltose and acting as a potent inhibitor of alpha-glucosidase enzymes, slowing down the digestion and absorption of complex carbohydrates. Synonyms: Glc(a1-4)Glc(a1-4)Glc(a1-6)Glc(a1-4)Glc(a1-4)Glc; alpha-D-gluco-hexopyranosyl-(1->4)-alpha-D-gluco-hexopyranosyl-(1->4)-alpha-D-gluco-hexopyranosyl-(1->6)-alpha-D-gluco-hexopyranosyl-(1->4)-alpha-D-gluco-hexopyranosyl-(1->4)-D-gluco-hexopyranose. Molecular formula: C36H62O31. Mole weight: 990.86. | |
8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - DY-480XL Quick inquiry Where to buy Suppliers range | DY-480XL, a biomedicine product specialized in biochemical studies, offers an intricate solution to understanding the dynamics of enzymatic interactions and signaling pathways. As a fluorescent analog of 2',5'-ADP, this product boasts the capability to study complex enzyme activities such as adenylate cyclase and cyclic nucleotide phosphodiesterase. Furthermore, it can delve into the intricate signaling pathways activated by extracellular receptors, which induce G protein-coupled pathways. The product's versatility renders it invaluable in the oncology research sphere, with its potential applications ranging from breast, ovarian to colon cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H57N9O16P2S (free acid). Mole weight: 1037.97 (free acid). | |
8-[(6-Amino)hexyl]-amino-ATP - ATTO-Rho14 Quick inquiry Where to buy Suppliers range | 8-[(6-Amino)hexyl]-amino-ATP, a fluorescent-labeled nucleotide, finds application in biomedical research to track and detect biomolecules central to ATP-mediated cell signaling pathways. Boasting high specificity for ATP-binding proteins, this product identifies and analyzes key enzymes involved in cellular metabolism and signaling pathways. Utilizing this nucleotide illuminates intricate pathways of cellular communication and aids researchers in deciphering the complex world of biochemical interactions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H71Cl4N10O16P3 (free acid). Mole weight: 1384.30 (free acid). | |
8-Azido-AMP Quick inquiry Where to buy Suppliers range | 8-Azido-AMP is also known as 8-Azidoadenosine monophosphate, facilitating the meticulous examination of intricate protein functionality, intricate protein-protein associations is and intricate enzymatic behavior. Additionally, it profoundly contributes to the elucidation and understanding of complex drug-target relationships and the enlightenment of promising therapeutic candidates targeting a wide spectrum of ailments. Synonyms: 8-Azido-adenosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H13N8O7P (free acid). Mole weight: 388.23 (free acid). | |
Abametapir Quick inquiry Where to buy Suppliers range | Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. Uses: 5,5'-dimethyl-2,2'-bipyridine is used in preparation of iron bipyridine acetoacetate complexes. Synonyms: 5,5'-Dimethyl-2,2'-bipyridine; 6,6'-Bi-3-picoline; 5,5'-Dimethyl-2,2'-bipyridyl. Grades: 98 %. CAS No. 1762-34-1. Molecular formula: C12H12N2. Mole weight: 184.24. | |
a-D-Glucuronic acid 1-phosphate tripotassium salt pentahydrate Quick inquiry Where to buy Suppliers range | a-D-Glucuronic acid 1-phosphate tripotassium salt pentahydrate, a pivotal compound in the field of biomedicine, holds paramount importance. It serves as a substrate in diverse enzymatic reactions, prominently contributing to the intricate metabolic processes of complex carbohydrates. Its profound anti-inflammatory properties have rendered it invaluable for the development of pharmaceutical formulations targeting chronic inflammatory ailments like rheumatoid arthritis and osteoarthritis. Synonyms: Potassium (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(phosphonatooxy)tetrahydro-2H-pyran-2-carboxylate pentahydrate; tripotassium; (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-phosphonatooxyoxane-2-carboxylate; pentahydrate. CAS No. 103213-29-2. Molecular formula: C6H8O10PNa3. Mole weight: 340.06. | |
α-Amino-hexyl-AMP Quick inquiry Where to buy Suppliers range | α-Amino-hexyl-AMP, otherwise known as 6-Aminohexyladenosine 5'-monophosphate, is an essential biological compound used in the intricate and complex synthesis of RNA and DNA. In addition, this powerful compound discloses tremendous potential to serve as an effective treatment for certain forms of cancer, as it possesses the capability to selectively dismantle and suppress the activity of tumorigenic enzymes that induce oncogenesis. With its further use as an activator of the immune system, it propels the immune response to fend off various types of viral infections and pathogens. Synonyms: α-(6-Aminohexyl)-adenosine-5'-monophosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H27N6O7P (free acid). Mole weight: 446.40 (free acid). | |
Aminooxyacetic Acid Quick inquiry Where to buy Suppliers range | Aminooxyacetic acid, often abbreviated AOA or AOAA, is a GABA transaminase (GABA-T) inhibitor (Ki = 9.16 μM) that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down. Subsequently, the level of GABA is increased in tissues. At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a useful tool to study regional GABA turnover in rats. AOAA is also an inhibitor of pyridoxal phosphate (PLP)-dependent enzymes, which serve as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes. Uses: Gaba agents. Synonyms: Aminooxyacetate; AOAA; 2-Aminooxyacetic acid; U 7524; U7524; U-7524. Grades: ≥95%. CAS No. 645-88-5. Molecular formula: C2H5NO3. Mole weight: 91.07. | |
Aprotinin Quick inquiry Where to buy Suppliers range | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. Synonyms: H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH; EC: 3.4.21.9; Iniprol; Trasylol; Trazinin; Zymofren; Riker 52G. Grades: >99%. CAS No. 9087-70-1. Molecular formula: C284H432N84O79S7. Mole weight: 6511.48. | |
Aprotinin, Bovine (Pancreatic trypsin inhibitor) Quick inquiry Where to buy Suppliers range | Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes, dissociating at pH >10 or <3. Effective concentration is equimolar with protease. Group: Biochemicals. Alternative Names: Antikrein; Antilysin; Antilysine; Aprostat; Aprotinin; BPTI; BPTI Trypsin Inhibitor; Basic Pancreatic Trypsin Inhibitor; Bayer A 128; Bovine Basic Pancreatic Trypsin Inhibitor; Bovine Pancreatic Trypsin Inhibitor; Bovine Trypsin Inhibitor; Fosten; Kallikrein-trypsin Inactivator; Kiker 52G; Kir Richter; Kunitz Pancreatic Trypsin Inhibitor; Kunitz Protease Inhibitor; Kunitz Trypsin Inhibitor; Kunitz-type Inhibitor; Kunitz-type Proteinase Inhibitor; Kunitz-type Trypsin Inhibitor; Onquinin; Pancreatic Basic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor (Kunitz); Protease Inhibitor, Kunitz Type; RP 9921; Repulson; Trasuylol; Trasylol; Trazinin; Triazinin; Trypsin Inhibitor, Trasylol; Trypsin-kallikrein Inhibitor (Kunitz); Zymofren. Grades: Highly Purified. CAS No. 9087-70-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C???H???N??O??S?, Molecular Weight: 6511.45. US Biological Life Sciences. | Worldwide |
BAY 56-3722 Quick inquiry Where to buy Suppliers range | BAY 56-3722 is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. The peptide carbohydrate moiety of this agent stabilizes the lactone form of camptothecin in blood. Synonyms: BAY-563722; BAY56 3722; BAY 38-3441; BAY 38 344; (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate. CAS No. 215604-75-4. Molecular formula: C45H50ClN7O11S. Mole weight: 895.98. | |
BAY 56-3722 hydrochloride Quick inquiry Where to buy Suppliers range | BAY 56-3722, a water-soluble camptothecin derivative, is a DNA-Intercalating drug that stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Synonyms: BAY 56-3722; BAY56-3722; BAY-56-3722; N-[4- (6-Deoxy-3-O-methyl-beta-L-galactopyranosyloxy) phenylaminothiocarbonyl]-L-histidyl-L-valine 4(S)-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ester hydrochloride; N-[4-(3-O-Methyl-beta-L-fucopyranosyloxy)p; Afeletecan hydrochloride; BAY 38-3441; L-Valine, N- ( ( (4- ( (6-deoxy-3-O-methyl-beta-L-galactopyranosyl) oxy) phenyl) amino) thioxomethyl) -L-histidyl-, (4S)-4-ethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-4-yl ester, hydrochloride (1:1); 215604-75-4 (BAY 56-3722 free base); 215604-74-3 (BAY 56-3722 HCl salt; 215604-66-3 (diastereomeric mixture). Grades: >98%. CAS No. 215604-74-3. Molecular formula: C45H49N7O11S.HCl. Mole weight: 932.447. | |
β-Cyclodextrin Quick inquiry Where to buy Suppliers range | β-cyclodextrin is a cyclic oligosaccharide produced from starch via enzymatic conversion. It is widely used in food, medicine, cosmetics, chemical and other industries. β-cyclodextrin is used as a complexing agent in drug delivery, increasing the water solubility, dissolution rate and bioavailability of poorly water-soluble drugs. β-Cyclodextrin is commonly used to produce HPLC columns that allow the separation of chiral enantiomers. Uses: Sequestering agents. Synonyms: Cycloheptaamylose; Adrabetadex; BCD; Betadex; BW 7 (polysaccharide); Cavamax W 7; Celdex N; Cibatex OC-CLD; Cyclodextrin Beta W 7M1.8; Cycloheptaglucan; Cycloheptaglucosan; Cyclomaltoheptaose; CYL 3190; Dexipar β-100; Dextrin, β-cyclo; Dexy Pearl 100; HP-β-CD; HRBS-Q 009; Kleptose; Kleptose B; Kleptose STD; NSC 269471; NSC 314334; Rhodocap N; Rindex B; Ringdex B; Ringdex BL; Schardinger β-dextrin; Stereoisomer of 5, 10, 15, 20, 25, 30, 35-heptakis(hydroxymethyl)-2, 4, 7, 9, 12, 14, 17, 19, 22, 24, 27, 29, 32, 34-tetradecaoxaoctacyclo[31.2.2.23, 6.28, 11.213, 16.218, 21.223, 26.228, 31]nonatetracontane-36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49-tetradecol; Trappsol Cyclo; VAR 200; VTS 270; β-Cycloamylose; β-Cycloheptaamylose; β-Dextrin. Grades: ≥95%. CAS No. 7585-39-9. Molecular formula: C42H70O35. Mole weight: 1134.98. | |
Bleomycin complex (as sulfate salts) Quick inquiry Where to buy Suppliers range | Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2 and typically represent >90% of the total weight with the remainder comprising the minor analogues. Bleomycins have found clinical application in the treatment of a range of tumors. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo- enzyme that induces DNA cleavage. Group: Biochemicals. Alternative Names: Blenoxane; Blexane; Bleo. Grades: Highly Purified. CAS No. 9041-93-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Bromelain Quick inquiry Where to buy Suppliers range | Bromelain is a protein-digesting enzyme extracted from the stem, fruit, and juice of the pineapple plant (Ananas comosus). It belongs to a group of enzymes called proteases or proteinases. Bromelain is a complex mixture of enzymes that can hydrolyze (break down) various types of proteins, including collagen, elastin, and fibrin. Uses: 1. Anti-inflammatory: Bromelain has been found to possess anti-inflammatory properties, which makes it useful in the treatment of arthritis, asthma, allergies, and other conditions characterized by inflammation. 2. Digestive aid: Bromelain is often used as a digestive aid because it helps break down proteins in the digestive tract, aiding digestion and reducing bloating. 3. Wound healing: Bromelain has been found to help reduce inflammation and promote healing, making it useful in the treatment of burns, injuries, and surgical wounds. 4. Cancer treatment: Bromelain has been suggested to have anti-cancer properties, with studies showing that it may help inhibit the growth of cancer cells. 5. Cardiovascular health: Bromelain has been found to have blood-thinning and cholesterol-lowering properties, which makes it useful in reducing the risk of heart disease. 6. Skin care: Bromelain is sometimes used as an ingredient in skin care products because of its ability to gently exfoliate the skin and help remove dead skin cells. 7. Sinusitis treatment: Because of its anti-inflammatory properties, bromelain has been found to be helpful in reducing nasal swelling and inflammation in people with sinusitis. Group: Skin Actives. Alternative Names: STEM BROMELAIN; 3.4.22.32; BROMELAIN; BROMELAIN PINEAPPLE;BROMELIN;EC 3.4.22.1;EC 3.4.22.32;EC 3.4.22.4. CAS No. 9001-00-7. Product ID: ACM9001007. Molecular formula: N/A. Mole weight: N/A. Appearance: yellow to beige crystalline powder. | |
Brostallicin hydrochloride Quick inquiry Where to buy Suppliers range | Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent appears to bind covalently to DNA in a different manner and its activity does not depend on a functional DNA mismatch repair (MMR) mechanism. Accordingly, brostallicin may be effective against MMR-defective tumors that are refractory to various anticancer agents. Synonyms: PNU-166196; PNU 166196; PNU166196; 4-(2-bromoacrylamido)-N-(5-(5-(5-(2-guanidinoethylcarbamoyl)-1-methyl- 1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H- pyrrol-3-yl)-1-methyl-1H-pyrrole-2-carboxamide. CAS No. 203258-38-2. Molecular formula: C30H36BrClN12O5. Mole weight: 760.05. | |
Carrot Cells Quick inquiry Where to buy Suppliers range | Intact isolated cells of fresh carrot roots made from a specific enzymatic micro-dissociation process. Carrot cells are rich in hydro-soluble and lipo-soluble nutrients. They remain intact and visible even in complex. 100% natural origin formulations. Uses: Anti-aging and anti-wrinkle creams, lotions, gels, sun care & makeup. Group: Skin Actives. CAS No. 284-545-1 / 7732-18-5. Product ID: ACM2845451. Appearance: Light-orange liquid. | |
Casein (EP) Quick inquiry Where to buy Suppliers range | Casein (EP). Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: Casein complexes, Caseins, salts, Caseinogen, Casein curd, Casecoat BL 330, Casein salts, FN 5, Protaflex, A 730, FR 17, FR 17 (casein), Casein, Caseinogen, Casesol, HC 200, Baysin Lustre K, Galalith, CAAS 3, Casinella QN, CAAS 2, Caseins, complexes,Casein, Alacid First 30M, Complexes caseins, Casein substitutes, Acid casein, BI 372, K 70 (casein), Pigment Binder AH, Casco A, Casinella QS, Dynosin N, Alacid Lactic Casein, Casein number, Alaren 786, Protoflex, Alacid 741, K 70, CTV, Isofar, Plastics, casein, CAAS 1, 4025LP, G 90W, Nutripro, FN 4, Alaren 711, BI 1346, A 730 (casein), Luron Binder UD, FUR 12. CAS No. 9000-71-9. Catalog: APS9000719. Format: Neat. Product Type: Other. Shipping: Room Temperature. | |
Chitosan-mPEG 1k Quick inquiry Where to buy Suppliers range | Chitosan-mPEG 1k. Uses: 1. Chitosan has in the last decades been widely used in a variety of applications, both industrially and pharmaceutically.2. Its positive charges under slightly acidic conditions allow it to form complexes or nanoparticles.3. During the delivery process, the stable compact structure of the complex, with cationic chitosan chains as the outershell and the anionic genes/drugs as the core, efficiently protects genes/drugs from the ?sweeping effect? of mucociliary clearance and degradation by enzymes. Group: Raw Materials. Alternative Names: Medium MW, PEGylated Chitosan. Pack Sizes: 500 mg. Product ID: MSMN-114. | |
Compound E Quick inquiry Where to buy Suppliers range | Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grades: 99%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5. | |
D-?Altritol, 2-?(6-?amino-?9H-?purin-?9-?yl)?-?1,?5-?anhydro-?2,?3-?dideoxy-?3-?fluoro- Quick inquiry Where to buy Suppliers range | D-Altritol, 2-(6-amino-9H-purin-9-yl)-1,5-anhydro-2,3-dideoxy-3-fluoro is a cutting-edge biomedical product primarily employed for studying the pernicious effects of viral infections. With its exceptional antiviral attributes, this compound selectively acts upon critical enzymes intricately involved in the complex process of viral replication. CAS No. 852234-78-7. Molecular formula: C11H14FN5O3. Mole weight: 283.26. | |
Doxorubicin, Hydrochloride (Adriacin, Adriblastina, Adriamycin, Caelyx) Quick inquiry Where to buy Suppliers range | The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. Group: Biochemicals. Alternative Names: Adriacin, Adriblastina, Adriamycin, Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
EDA-IDP Quick inquiry Where to buy Suppliers range | EDA-IDP is a potent compound aiming to study the perplexing realm of neurodegenerative disorders. Specifically designed to study the enigmatic complexities associated with Alzheimer's disease, this prodigious product exhibits unparalleled prowess in modulating the intricate enzymatic pathways involved in the synthesis of amyloid-beta peptides. By meticulously inhibiting the nefarious aggregation of amyloid-beta, EDA-IDP harmoniously orchestrates a resolute reduction in neurotoxicity, subsequently studying the relentless progression of Alzheimer's disease. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Inosine-5'-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C13H20N6O12P2(free acid). Mole weight: 514.28 (free acid). | |
Edotecarin Quick inquiry Where to buy Suppliers range | Edotecarin is a synthetic indolocarbazole with antineoplastic activity. Edotecarin inhibits the enzyme topoisomerase I through stabilization of the DNA-enzyme complex and enhanced single-strand DNA cleavage, resulting in inhibition of DNA replication and decreased tumor cell proliferation. Synonyms: J 107088; PF 804950; 5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, 12-β-D-glucopyranosyl-12,13-dihydro-2,10-dihydroxy-6-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-; 6-[(1,3-Dihydroxy-2-propanyl)amino]-12-(β-D-glucopyranosyl)-2,10-dihydroxy-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grades: ≥95%. CAS No. 174402-32-5. Molecular formula: C29H28N4O11. Mole weight: 608.56. | |
Ethonafide Quick inquiry Where to buy Suppliers range | Ethonafide is an anthracene-containing derivative of amonafide that belongs to the azonafide series of anticancer agents. The lack of cross-resistance in multidrug-resistant cancer cell lines and the absence of a quinone and hydroquinone moiety make ethonafide a potentially less cardiotoxic replacement for existing anthracene-containing anticancer agents. Ethonafide was cytotoxic against three human prostate cancer cell lines at nanomolar concentrations. Ethonafide was found to be better tolerated and more effective at inhibiting tumor growth compared with mitoxantrone in a human xenograft tumor regression mouse model. Mechanistically, we found that ethonafide inhibited topoisomerase II activity by stabilizing the enzyme-DNA complex, involving both topoisomerase IIalpha and -beta. In addition, ethonafide induced a potent G(2) cell cycle arrest in the DU 145 human prostate cancer cell line. By creating stable cell lines with decreased expression of topoisomerase IIalpha or -beta, we found that a decrease in topoisomerase IIalpha protein expression renders the cell line resistant to ethonafide. The decrease in sensitivity to ethonafide was associated with a decrease in DNA damage and an increase in DNA repair as measured by the neutral comet assay. These data demonstrate that ethonafide is a topoisomerase II poison and that it is topoisomerase IIalpha-specific in the DU 145 human prostate cancer cell line. Uses: Topoisomerase ii inhibitors. Synonyms: AMP-53; AMP 53; AMP53; 2-(2'-(Dimethylamino)ethyl)-1,2-dihydro-7-ethoxydibenz(de, H)isoquinoline-1,3-dione; 2-[2-(Dimethylamino)ethyl]-7-ethoxy-1H-dibenz[de,h]isoquinoline-1,3(2H)-dione. CAS No. 175293-23-9. Molecular formula: C22H22N2O3. Mole weight: 362.43. | |
Ethyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-thioglucopyranoside Quick inquiry Where to buy Suppliers range | Ethyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-thioglucopyranoside is a complex and intriguing compound, tailored to target precise proteins or enzymes associated with inflammatory processes, oncogenesis, or infectious ailments. Synonyms: [(2R,3S,4R,5R,6S)-5-(1,3-dioxoisoindol-2-yl)-6-ethylsulfanyl-4-phenylmethoxy-2-(phenylmethoxymethyl)oxan-3-yl] acetate; (2R,3S,4R,5R,6S)-4-(Benzyloxy)-2-((benzyloxy)methyl)-5-(1,3-dioxoisoindolin-2-yl)-6-(ethylthio)tetrahydro-2H-pyran-3-yl acetate. CAS No. 138730-66-2. Molecular formula: C32H33NO7S. Mole weight: 575.7. |