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copalyl diphosphate synthase In some plants, such as Salvia miltiorrhiza, this enzyme is monofunctional. In other plants this activity is often a part of a bifunctional enzyme. For example, in Selaginella moellendorffii this activity is catalysed by a bifunctional enzyme that also catalyses EC 4.2.3.131, miltiradiene synthase, while in the tree Abies grandis (grand fir) it is catalysed by a bifunctional enzyme that also catalyses EC 4.2.3.18, abietadiene synthase. Group: Enzymes. Synonyms: (+)-copalyl-diphosphate lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.12. CAS No. 157972-08-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5613; copalyl diphosphate synthase; EC 5.5.1.12; 157972-08-2; (+)-copalyl-diphosphate lyase (decyclizing). Cat No: EXWM-5613. Creative Enzymes
ent-copalyl diphosphate synthase Part of a bifunctional enzyme involved in the biosynthesis of kaurene. See also EC 4.2.3.19 (ent-kaurene synthase). Group: Enzymes. Synonyms: ent-kaurene synthase A; ent-kaurene synthetase A; ent-CDP synthase; ent-copalyl-diphosphate lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.13. CAS No. 9055-64-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5614; ent-copalyl diphosphate synthase; EC 5.5.1.13; 9055-64-5; ent-kaurene synthase A; ent-kaurene synthetase A; ent-CDP synthase; ent-copalyl-diphosphate lyase (decyclizing). Cat No: EXWM-5614. Creative Enzymes
syn-copalyl-diphosphate synthase Requires a divalent metal ion, preferably Mg2+, for activity. This class II terpene synthase produces syn-copalyl diphosphate, a precursor of several rice phytoalexins, including oryzalexin S and momilactones A and B. Phytoalexins are diterpenoid secondary metabolites that are involved in the defense mechanism of the plant, and are produced in response to pathogen attack through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation. The enzyme is constitutively expressed in the roots of plants where one of its products, momilactone B, acts as an allelochemical (a molecule released into the environment to suppress the growth of neighbouring plants). In other tissues the enzyme is upregulated by conditions that stimulate the biosynthesis of phytoalexins. Group: Enzymes. Synonyms: OsCyc1; OsCPSsyn; syn-CPP synthase; syn-copalyl diphosphate synthase; 9α-copalyl-diphosphate lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5615; syn-copalyl-diphosphate synthase; EC 5.5.1.14; OsCyc1; OsCPSsyn; syn-CPP synthase; syn-copalyl diphosphate synthase; 9α-copalyl-diphosphate lyase (decyclizing). Cat No: EXWM-5615. Creative Enzymes
abieta-7,13-diene synthase Part of a bifunctional enzyme involved in the biosynthesis of abietadiene. See also EC 5.5.1.12, copalyl diphosphate synthase. Requires Mg2+. Creative Enzymes
abieta-7,13-diene synthase Part of a bifunctional enzyme involved in the biosynthesis of abietadiene. See also EC 5.5.1.12, copalyl diphosphate synthase. Requires Mg2+. Group: Enzymes. Synonyms: copalyl-diphosphate diphosphate-lyase (cyclizing) (ambiguous); abietadiene synthase (ambiguous). Enzyme Commission Number: EC 4.2.3.18. CAS No. 157972-08-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5174; abieta-7,13-diene synthase; EC 4.2.3.18; 157972-08-2; copalyl-diphosphate diphosphate-lyase (cyclizing) (ambiguous); abietadiene synthase (ambiguous). Cat No: EXWM-5174. Creative Enzymes
aphidicolan-16β-ol synthase This is a bifunctional enzyme which also has EC 5.5.1.14 syn-copalyl diphosphate synthase activity. Aphidicolan-16β-ol is a precursor of aphidicolin, a specific inhibitor of DNA polymerase α (EC 2.7.7.7). Group: Enzymes. Synonyms: PbACS. Enzyme Commission Number: EC 4.2.3.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5201; aphidicolan-16β-ol synthase; EC 4.2.3.42; PbACS. Cat No: EXWM-5201. Creative Enzymes
ent-kaurene synthase Part of a bifunctional enzyme involved in the biosynthesis of ent-kaurene. See also EC 5.5.1.13 (ent-copalyl diphosphate synthase). Group: Enzymes. Synonyms: ent-kaurene synthase B; ent-kaurene synthetase B, ent-copalyl-diphosphate diphosphate-lyase (cyclizing). Enzyme Commission Number: EC 4.2.3.19. CAS No. 9055-64-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5175; ent-kaurene synthase; EC 4.2.3.19; 9055-64-5; ent-kaurene synthase B; ent-kaurene synthetase B, ent-copalyl-diphosphate diphosphate-lyase (cyclizing). Cat No: EXWM-5175. Creative Enzymes
isopimara-7,15-diene synthase The enzyme only gave isopimara-7,15-diene. Group: Enzymes. Synonyms: PaTPS-Iso; copalyl diphosphate-lyase (isopimara-7,15-diene-forming). Enzyme Commission Number: EC 4.2.3.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5203; isopimara-7,15-diene synthase; EC 4.2.3.44; PaTPS-Iso; copalyl diphosphate-lyase (isopimara-7,15-diene-forming). Cat No: EXWM-5203. Creative Enzymes
labdatriene synthase The enzyme from rice (Oryza sativa), expressed in Escherichia coli, also produces ent-sandaracopimara-8(14),15-diene from ent-copalyl diphosphate, another naturally occuring copalyl isomer in rice (cf. ent-sandaracopimaradiene synthase, EC 4.2.3.29). Group: Enzymes. Synonyms: OsKSL10 (gene name). Enzyme Commission Number: EC 4.2.3.99. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5263; labdatriene synthase; EC 4.2.3.99; OsKSL10 (gene name). Cat No: EXWM-5263. Creative Enzymes
levopimaradiene synthase In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists. Levopimaradiene is widely distributed in higher plants. In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene. Group: Enzymes. Synonyms: PtTPS-LAS; LPS; copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]. Enzyme Commission Number: EC 4.2.3.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5190; levopimaradiene synthase; EC 4.2.3.32; PtTPS-LAS; LPS; copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]. Cat No: EXWM-5190. Creative Enzymes
miltiradiene synthase Isolated from the plants Rosmarinus officinalis (rosemary) and Salvia miltiorrhiza. The enzyme from the plant Selaginella moellendorffii is mutifunctional and also catalyses EC 5.5.1.12, copalyl diphosphate synthase. Group: Enzymes. Synonyms: SmMDS; SmiKSL; RoKSL. Enzyme Commission Number: EC 4.2.3.131. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5145; miltiradiene synthase; EC 4.2.3.131; SmMDS; SmiKSL; RoKSL. Cat No: EXWM-5145. Creative Enzymes
neoabietadiene synthase Isolated from Abies grandis (grand fir). This class I enzyme forms about equal proportions of abietadiene, levopimaradiene and neoabietadiene. See also EC 4.2.3.18, abieta-7,13-diene synthase and EC 4.2.3.32, levopimaradiene synthase. An X-ray study of this multifunctional enzyme showed that the class I activity is in the α domain, while (+)-copalyl diphosphate synthase activity (EC 5.5.1.12, a class II activity) is in the β and γ domains. In Pinus taeda (loblolly pine) the major product is levopimaradiene, with less abietadiene and neoabietadiene. Group: Enzymes. Synonyms: AgAS; PtTPS-LAS. Enzyme Commission Number: EC 4.2.3.132. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5146; neoabietadiene synthase; EC 4.2.3.132; AgAS; PtTPS-LAS. Cat No: EXWM-5146. Creative Enzymes
phyllocladan-16α-ol synthase The adjacent gene PaDC2 codes EC 5.5.1.12 copalyl diphosphate synthase. Group: Enzymes. Synonyms: PaDC1. Enzyme Commission Number: EC 4.2.3.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5204; phyllocladan-16α-ol synthase; EC 4.2.3.45; PaDC1. Cat No: EXWM-5204. Creative Enzymes

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