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| Product | Description | |
|---|---|---|
| Corylin | Corylin. Group: Biochemicals. Grades: Plant Grade. CAS No. 53947-92-5. Pack Sizes: 20mg. Molecular Formula: C20H16O4, Molecular Weight: 320.34. US Biological Life Sciences. |  Worldwide |
| Corylin | Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound.IC50 value:Target:in vitro: Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 53947-92-5. Molecular formula: C20H16O4. Mole weight: 320.34. Purity: 0.98. IUPACName: 3-(2,2-Dimethylchromen-6-yl)-7-hydroxychromen-4-one. Canonical SMILES: CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C. Density: 1.295±0.06 g/ml. Product ID: ACM53947925. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cory in the House. |  |
| Corylin | Corylin is an orally active flavonoid anti-inflammatory and osteogenic agent that inhibits IL-6-induced STAT3 promoter activity and STAT3 phosphorylation. Corylin also has anticancer, antiatherosclerotic, and ameliorating activity in hyperlipidemia and insulin resistance, inducing adipocyte browning and lipolysis through SIRT1 or β3-AR-dependent pathways [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 53947-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0236. |  |
| Bavachalcone | Bavachalcone inhibited osteoclast formation from precursor cells with the IC(50) of approximately 1.5 microg ml(-1). The activation of MEK, ERK, and Akt by receptor activator of nuclear factor kappaB ligand (RANKL), the osteoclast differentiation factor, was prominently reduced in the presence of bavachalcone. The induction of c-Fos and NFATc1, key transcription factors for osteoclastogenesis, by RANKL was also suppressed by bavachalcone. Bavachalcone exhibited a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro. Bavachalcone had stronger inhibition on UGT1A1 and UGT1A7 than corylin which did not inhibit UGT1A1, UGT1A3, UGT1A7, UGT1A8, UGT1A10, and UGT2B4. Data fitting using Dixon and Lineweaver-Burk plots demonstrated the noncompetitive inhibition of bavachalcone against UGT1A1 and UGT1A7-mediated 4-MU glucuronidation reaction. The values of inhibition kinetic parameters (Ki) were 5.41 μ M and 4.51μ M for UGT1A1 and UGT1A7, respectively. Synonyms: Broussochalcone B. Grades: >98%. CAS No. 28448-85-3. Molecular formula: C20H20O4. Mole weight: 324.37. |  |
| Corylifol A | Corylifol A. Group: Biochemicals. Alternative Names: 3?-Geranyl-4?,7-dihydroxyisoflavone; Corylinin. Grades: Plant Grade. CAS No. 775351-88-7. Pack Sizes: 20mg. Molecular Formula: C25H26O4, Molecular Weight: 390.472. US Biological Life Sciences. | Worldwide |
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