Cyclohydrolase Suppliers USA
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Product | Description | |
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ATIC Dimerization Inhibitor (Ac-Arg-Ph(4-NO2)-NEt2, ATIC Inhibitor, AICAR Tfase Inhibitor, AICAR Transformylase Inhibitor, AICAR Tranformylase/Inosine Monophosphate Cyclohydrolase Dimerization Inhibitor, AMPK Signaling Activator XI) Quick inquiry Where to buy Suppliers range | A cell-permeable dipeptide that reversibly blocks the homodimerization of aminoimidazole carboxamide ribonucleotide transformylase/inosine nomophosphate cyclohydrolase (ATIC) and inhibits its activity (Ki = 691nM, Kd = 240nM). AITC is a bifunctional enzyme that catalyzes the last two steps of de novo purine biosynthesis. Increases the intracellular levels of AICAR leading to the activation of AMP-activated protein kinase (AMPK). Shown to reduce cell viability in a dose-dependent manner. Exhibits a longer half-life and sustained AMPK activation (~24h), compared to AICA-riboside. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
6,7-Dimethyltetrahydropterin hydrochloride Quick inquiry Where to buy Suppliers range | 6,7-Dimethyltetrahydropterin is a non-competitive inhibitor of GTP cyclohydrolase I exhibiting an IC50 of 76-112 μM. Synonyms: 2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride. Grades: ≥99%. CAS No. 167423-51-0. Molecular formula: C8H13N5O·HCl. Mole weight: 231.7. | |
7,8-dihydro biopterin Quick inquiry Where to buy Suppliers range | 7,8-dihydro biopterin is a precursor of BH4 synthesis and a noncompetitive inhibitor of GCH-I (GTP cyclohydrolase I). It is the reduced form of Biopterin. Synonyms: 7,8-Dihydro-L-biopterin; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; L-erythro-7,8-Dihydrobiopterin; L-erythro-Dihydrobiopterin. Grades: > 95%. CAS No. 6779-87-9. Molecular formula: C9H13N5O3. Mole weight: 239.24. |