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Cylindrospermopsin is a cyanotoxin produced by a variety of freshwater cyanobacteria. It is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4(1h,3h)-pyrimidinedione,6-(hydroxy(2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(;5a-alpha,7-beta(r*))-(-)-h;cylindrospermopsin;sulfooxy)-1h-1,8,8b-triazaacenaphthylen-7-yl)methyl)-,(2a-alpha,3-alpha,4-alp;6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione. Product Category: Inhibitors. Appearance: white powder. CAS No. 143545-90-8. Molecular formula: C15H21N5O7S. Mole weight: 415.425. Canonical SMILES: O[C@H]([C@]1([H])N=C2N([C@@](CN2)([H])[C@@H](C)[C@@H](OS(=O)(O)=O)C3)[C@@]3([H])C1)C(NC4=O)=CC(N4)=O. Product ID: ACM143545908. Alfa Chemistry ISO 9001:2015 Certified.
Cylindrospermopsin
It is produced by the strain of Cylindrospermopsis raciborskii. Cylindrospermopsin is a tricyclic uracil derivative which is a cyanobacterial toxin. And it targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 μM, respectively), leading to cell death. It has been proved to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 μM. Synonyms: [2aS-[2aα, 3α, 4α, 5aα, 7β(S*)]]-6-[Hydroxy[2, 2a, 3, 4, 5, 5a, 6, 7-octahydro-3-methyl-4-(sulfooxy)-1H-1, 8, 8b-triazaacenaphthylen-7-yl]methyl]-2, 4(1H, 3H)-pyrimidinedione; 6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; Cylindrospermopsine. Grades: ≥95%. CAS No. 143545-90-8. Molecular formula: C15H21N5O7S. Mole weight: 415.43.
Cylindrospermopsin (NRC Certified Calibration Solution). Concentration: 30 μmol/L of CYN in Filtered, Deionized Water
Cylindrospermopsin is a cyanobacterial toxin associated with poisoning incidents. Group: Biochemicals. Grades: Highly Purified. CAS No. 143545-90-8. Pack Sizes: 500ul. Molecular Formula: C15H21N5O7S, Molecular Weight: 415.42. US Biological Life Sciences.
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2,4-Dimethoxypyrimidine-6-carboxylic Acid
2,4-Dimethoxypyrimidine-6-carboxylic Acid is a reactant or reagent in the synthetic preparation of racemic cylindrospermopsin. Group: Biochemicals. Grades: Highly Purified. CAS No. 59864-30-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H8N2O4, Molecular Weight: 184.15. US Biological Life Sciences.
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(2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine
(2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine is a reactant or reagent. Early intermediate for syntheses of the cylindrospermopsin and related alkaloids via intramolecular 1,3-dipolar cycloaddition reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 112741-50-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C21H23NO4, Molecular Weight: 353.41. US Biological Life Sciences.
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