Cysteine Synthase Suppliers USA
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Product | Description | |
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BEC Quick inquiry Where to buy Suppliers range | BEC, also known as S-(2-boronoethyl)-L-cysteine, is a slow-binding competitive inhibitor of recombinant rat liver arginase I with Ki values of 0.4-0.6 μM from kinetic analyses. It significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM. BEC does not inhibit NO synthase, and effectively prevented ACh tolerance in aortic and mesenteric artery preparations. Synonyms: S-(2-boronoethyl)-L-cysteine. Grades: ≥98%. CAS No. 63107-40-4. Molecular formula: C5H12BNO4S. Mole weight: 193. | |
Calpain Inhibitor II Quick inquiry Where to buy Suppliers range | Calpain inhibitor II is a cell-permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). It inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Calpain inhibitor II can block nitric oxide production by interfering with transcription of the inducible nitric oxide synthase gene, which is a weak inhibitor of proteasome. It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems. Uses: Cysteine proteinase inhibitors. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-; L-Leucinamide, N-acetyl-L-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-; N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide; ALLM; Calp II; CI 2; SUAM 312; N-acetylleucyl-leucyl-methioninal; Ac-Leu-Leu-Met-al; N-acetyl-L-leucyl-L-leucyl-L-methioninal. Grades: ≥98%. CAS No. 110115-07-6. Molecular formula: C19H35N3O4S. Mole weight: 401.57. | |
Cindunistat Quick inquiry Where to buy Suppliers range | Cindunistat is a potent and oral selective iNOS inhibitor, potentially useful in patients with symptomatic osteoarthritis of the knee. Uses: Nitric oxide synthase type ii inhibitor. Synonyms: SC-84250; SC 84250; SC84250; SD-6010; SD 6010; SD6010; S-(2-(Acetimidoylamino)ethyl)-2-methyl-L-cysteine. Grades: ≥98%. CAS No. 364067-22-1. Molecular formula: C8H17N3O2S. Mole weight: 219.30. | |
Cysteine, S-Nitrosylated (SNO-Cys) (BSA) Quick inquiry Where to buy Suppliers range | Nitric oxide (NO), generated by cell type-specific NO- synthase (NOS) isoforms, is a freely diffusible intercellular messenger that functions in target cells in NOS-dependent signaling. S-nitrosylation of cysteine thiols in proteins by the highly labile NO radical has been identified as an important effector of NO-related bioactivity both in NOS- containing cells and intercellular signaling. Most cells contain low levels of nitrosylated proteins that are thought to be regulated by S-nitrosylation and denitrosylation. S-nitrosylation of proteins serves as a ubiquitous post- translational modification that dynamically regulates a broad functional spectrum of proteins. The majority of these proteins are regulated by S-nitrosylation on a single critical cysteine residue within an acidic/basic or hydrophobic structural motif that may also be subject to oxygen- or glutathione-dependent modification. NO- sensitive ion channels including the cardiac and skeletal muscle ryanodine receptor (RyR1 Group: Biochemicals. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
Leukotriene C4 Quick inquiry Where to buy Suppliers range | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4; 5S,6R-Ltc(sub 4); 6R-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5S-hydroxyicosa-7E,9E,11Z,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.78. | |
Leukotriene C4 methyl ester Quick inquiry Where to buy Suppliers range | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4 methyl ester; Leukotriene C4 monomethyl ester. Grades: ≥97%. CAS No. 73958-10-8. Molecular formula: C31H49N3O9S. Mole weight: 639.8. |