Cytochrome Reductase Suppliers USA
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Product | Description | |
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Cycloguanil hydrochloride Quick inquiry Where to buy Suppliers range | Cycloguanil is an active metabolite of proguanil, produced by the cytochrome P450 2C19 isoform. It is also an inhibitor of dihydrofolate reductase (DHFR) (Kis = 0.3 and 1.5 nM for Plasmodium and human forms, respectively). Uses: Antimalarials. Synonyms: Chloroguanide Triazine; NSC 3074; 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine monohydrochloride. Grades: ≥95%. CAS No. 152-53-4. Molecular formula: C11H14ClN5·HCl. Mole weight: 288.2. | |
HQNO Quick inquiry Where to buy Suppliers range | It is produced by the strain of Pseudomonas pyocyanea, P. aeruginosa, P. methanica. HQNO is a quinolone inhibitor that blocks NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR). It has weak anti-gram-positive bacterial activity. It can inhibit the microsomal respiratory chain and 5-lipoxygenase of cytochrome BC1 complex, and antagonize the antibacterial activity of dihydrostreptomycin. Synonyms: Antibiotic KF 8940; 2-Heptyl-1-hydroxy-4-(1H)-quinolinone; 2-heptyl-4-hydroxyquinoline n-oxide; HOQNO; 2-Heptyl-4-quinolinol 1-oxide; 2-heptylquinolin-4-ol 1-oxide; 2-(n-Heptyl)-4-hydroxyquinoline N-oxide. Grades: ≥98%. CAS No. 341-88-8. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
Naringenin Quick inquiry Where to buy Suppliers range | The aglucon of naringin. Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. It is the predominant flavanone in grapefruit. This substance has also been shown to reduce oxidative damage to DNA in vitro. Scientists exposed cells to 80 micromoles of naringenin per liter, for 24 hours, and found that the amount of hydroxyl damage to the DNA was reduced by 24% in that very short period of time.Naringenin found in grapefruit juice has been shown to have an inhibitory effect on the human cytochrome P450 isoform CYP1A2, which can change pharmacokinetics in a human (or orthologous) host of several popular drugs in an adverse manner, even resulting in carcinogens of otherwise harmless substances.Naringenin has also been shown to reduce hepatitis C virus production by infected hepatocytes (liver cells) in cell culture. This seem to be secondary to Naringenin ability to inhibit the secretion of very-low-density lipoprotein by the cells.Naringenin seems to protect LDLR-deficient mice from the obesity effects of a high-fat diet.Naringenin lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed a high-cholesterol diet. Group: Biochemicals. Alternative Names: 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (R,S)-Naringenin; (+/-)-5,7,4-Trihydroxyflavanone; 5,7,4-Trihydroxyflavanone. Grades: Highly Purified. CAS No. 67604-48-2. Pack Sizes: 10g. Molecular Formula: C??H??O?, Molecular Weight: 272.25. US Biological Life Sciences. | Worldwide |