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Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-2-Hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid. Product Category: Inhibitors. Appearance: Light beige solid. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17. Purity: 0.98. IUPACName: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid. Canonical SMILES: C1=CC(=C(C=C1C[C@H](C(=O)O)O)O)O. Density: 1.546 g/ml. Product ID: ACM76822214. Alfa Chemistry ISO 9001:2015 Certified.
Danshensu
Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species ( ROS ) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC 50 of 0.97?μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Dan shen suan A; Salvianic acid A. CAS No. 76822-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N1913.
Danshensu
Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhibits platelet adhesion and aggregation. It also protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation. It increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. It may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. It significantly decreased the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size in vitro. It also had ROS scavenging activity and boosted endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which was mediated by Akt and ERK1/2 in western blot analysis. It significantly lowered tHcy in rats with elevated tHcy. Danshensu is a natural compound, which can also be used in cosmetics material. Synonyms: Benzenepropanoic acid, α,3,4-trihydroxy-, (αR)-; (αR)-α,3,4-Trihydroxybenzenepropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, (R)-; (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid; (R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid; 3-(3',4'-Dihydroxyphenyl)-(2R)-lactic acid; D-(+)-β-(3,4-Dihydroxyphenyl)lactic acid; Dan Shen Su; Dan shen suan A; DS 182; Salianic acid A; Salvianic acid A; Tanshinol. Grades: >98%. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17.
Danshensu sodium
Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species ( ROS ) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC 50 of 0.97?μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Dan shen suan A sodium; Salvianic acid A sodium. CAS No. 81075-52-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1913A.
Sodium Danshensu
Sodium Danshensu. Group: Biochemicals. Grades: Highly Purified. CAS No. 76822-21-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H12O5Na. US Biological Life Sciences.
Worldwide
Danshen Root Extract (Standard)
Danshen Root Extract (Standard). Applications: Role of coronary artery: treatment of coronary heart disease, can improve the coronary circulation, inhibit thrombosis disease. danshensu a significant expansion of coronary artery, increase coronary blood flow, reducing myocardial oxygen consumption, heart rate and increase the role of myocardial contractility; danshen capsule expansion animals comfortable arteriole, the capillary network and opening up in number and speed up the flow of blood , flow, thus improving microcirculation; anti-infective; for the treatment of cervical erosion. Group: Others. Synonyms: Danshen Root Extract (Standard). Purity: 3%, 5%, 10%, 20%, HPLC. Appearance: Brown-red powder. Storage: 24 months with original packing under 18°C. Store in cool dry place,avoid sunlight and high temperature. Source: Salvia miltiorrhiza Bge. Danshen Root Extract (Standard); plant extract. Pack: 1kg, 5kg, 10kg aluminum foil vacuum bag; or 20kg, 25kg Fiber Drum. Cat No: EXTW-205.
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