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| Product | Description | |
|---|---|---|
| Daphnetin | Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne , is a potent, oral active protein kinase inhibitor, with IC 50 s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1 , ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 7,8-Dihydroxycoumarin. CAS No. 486-35-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0281. |  |
| Daphnetin | Daphnetin. Group: Biochemicals. Alternative Names: 7,8-Dihydroxycoumarin; Daphnetol. Grades: Plant Grade. CAS No. 486-35-1. Pack Sizes: 20mg. Molecular Formula: C9H6O4, Molecular Weight: 178.142. US Biological Life Sciences. |  Worldwide |
| Daphnetin dimethyl ether | Daphnetin dimethyl ether is a coumarin isolated from Artemisia caruifolia. Synonyms: 7,8-Dimethoxycoumarin; 7,8-dimethoxychromen-2-one. Grades: 0.98. CAS No. 2445-80-9. Molecular formula: C11H10O4. Mole weight: 206.19. |  |
| 5-hydroxyfuranocoumarin 5-O-methyltransferase | Converts bergaptol into bergapten, which has therapeutic potential in the treatment of psoriasis as it has photosensitizing and antiproliferative activities. The enzyme methylates the 5-hydroxy group of some hydroxy- and methylcoumarins, such as 5-hydroxyxanthotoxin, but has little activity on non-coumarin phenols. Caffeate, 5-hydroxyferulate and daphnetin are not substrates. Cu2+, Zn2+ and Co2+ cause enzyme inhibition. (see also EC 2.1.1.70, 8-hydroxyfuranocoumarin 8-O-methyltransferase). Group: Enzymes. Synonyms: furanocoumarin 5-methyltransferase; furanocoumarin 5-O-methyltransferase; bergaptol 5-O-methyltransferase; bergaptol O-methyltransferase; bergaptol methyltransferase; S-adenosyl-L-methionine:bergaptol O-methyltransferas. Enzyme Commission Number: EC 2.1.1.69. CAS No. 67339-12-2, 101637-31-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1970; 5-hydroxyfuranocoumarin 5-O-methyltransferase; EC 2.1.1.69; 67339-12-2, 101637-31-4; furanocoumarin 5-methyltransferase; furanocoumarin 5-O-methyltransferase; bergaptol 5-O-methyltransferase; bergaptol O-methyltransferase; bergaptol methyltransferase; S-adenosyl-L-methionine:bergaptol O-methyltransferase; BMT; S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase. Cat No: EXWM-1970. |  |
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