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| Product | Description | |
|---|---|---|
| Deleobuvir | Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including faldaprevir. Deleobuvir showed that a triple combination of deleobuvir, faldaprevir, and ribavirin performed well in HCV genotype 1b patients. Efficacy fell below 50%, however, for dual regimens without ribavirin and for genotype 1a patients. In December 2013, deleobuvir was discontinued since recent findings from phase III trials did not suggest sufficient efficacy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI207127; BI-207127; BI 207127; Deleobuvir; BI-207127NA; BI-207127Na. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 863884-77-9. Molecular formula: C34H33BrN6O3. Mole weight: 653.58. Purity: >98%. IUPACName: (E)-3-(2-(1-(2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carboxamido)cyclobutyl)-1-methyl-1H-benzo[d]imidazol-6-yl)acrylic acid. Canonical SMILES: O=C(O)/C=C/C1=CC=C2N=C(C3(NC(C4=CC5=C(C=C4)C(C6CCCC6)=C(C7=NC=C(Br)C=N7)N5C)=O)CCC3)N(C)C2=C1. Product ID: ACM863884779. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Deleobuvir | Deleobuvir (BI 207127) is a potent non-nucleoside hepatitis C virus (HCV) NS5B polymerase inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 207127. CAS No. 863884-77-9. Pack Sizes: 1 mg. Product ID: HY-12634. |  |
| 2,4-Dichloro-1-nitrobenzene | 2,4-Dichloro-1-nitrobenzene is used as a reagent in the synthesis of the hepatitis C virus polymerase inhibitor, Deleobuvir (BI 207127). Group: Biochemicals. Grades: Highly Purified. CAS No. 611-06-3. Pack Sizes: 1g, 5g. Molecular Formula: C6H3Cl2NO2. US Biological Life Sciences. |  Worldwide |
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