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| Product | Description | |
|---|---|---|
| Delgocitinib | Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Delgocitinib; LEO-124249; LEO124249; LEO 124249; JTE-052; JTE 052; JTE052. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1263774-59-9. Molecular formula: C16H18N6O. Mole weight: 310.36. Purity: >98%. IUPACName: 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile. Canonical SMILES: N#CCC(N1C[C@H](C)[C@]12CN(C3=C4C(NC=C4)=NC=N3)CC2)=O. Product ID: ACM1263774599. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Delgocitinib | Delgocitinib (JTE-052) is a specific JAK inhibitor with IC 50 s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JTE-052. CAS No. 1263774-59-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109053. |  |
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