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1-Demethylcolchicine is a derivative of Colchicine (C640000) an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 3464-68-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C21H23NO6, Molecular Weight: 385.41. US Biological Life Sciences.
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2-Allyl-2-demethyl 10-Tosyl-10-demethylColchicine
2-Allyl-2-demethyl 10-Tosyl-10-demethylColchicine is an intermediate in synthesizing Isothiocolcicoside (I902755), which is an impurity of Thiocolchicoside (T344385), a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C30H31NO8S. US Biological Life Sciences.
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2-Allyl-2-demethyl 9-Tosyl 10-DemethylColchicine
2-Allyl-2-demethyl 9-Tosyl 10-DemethylColchicine is an intermediate in synthesizing Isothiocolcicoside (I902755), which is an impurity of Thiocolchicoside (T344385), a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C30H31NO8S. US Biological Life Sciences.
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2-Allyl-2-demethyl-colchicine
2-Allyl-2-demethyl-colchicine is an intermediate in synthesizing Isothiocolcicoside (I902755), which is an impurity of Thiocolchicoside (T344385), a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 104158-07-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C24H27NO6. US Biological Life Sciences.
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2-Demethylcolchicine
2-Demethylcolchicine. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; O2-Demethylcolchicine; (-)-2-Demethylcolchicine. Grades: Highly Purified. CAS No. 102491-80-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H23NO6. US Biological Life Sciences.
2-DemethylColchicine is a metabolite of Colchicine. It has shown anti-tumor activity. Synonyms: N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; O2-Demethylcolchicine; (-)-2-Demethylcolchicine; NSC 180533. Grades: > 95%. CAS No. 102491-80-5. Molecular formula: C21H23NO6. Mole weight: 385.41.
2-DemethylColchicine 2-O-Sulfate
2-DemethylColchicine 2-O-Sulfate is the sulfate analogue of the 2-O-desmethyl metabolite of Colchicine. Synonyms: N-[(7S)-5,6,7,9-Tetrahydro-2-sulfooxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide. Grades: > 95%. CAS No. 1391052-56-4. Molecular formula: C21H23NO9S. Mole weight: 465.47.
2-Demethylcolchicine-d3
A labeled metabolite of Colchicine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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3-DemethylColchicine
A metabolite of Colchicine. Has shown anti-tumor activity. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-acetamide; O3-Demethylcolchicine; 3-Demethyl-(-)-colchicine; 3-Demethylcolchicine; 3-Desmethylcolchicine; O3-Demethylcolchicine. Grades: Highly Purified. CAS No. 7336-33-6. Pack Sizes: 50mg. US Biological Life Sciences.
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3-DemethylColchicine
Cas No. 7336-33-6.
3-Demethylcolchicine 3-O-b-D-glucuronide
3-Demethylcolchicine 3-O-b-D-glucuronide is a potent medicinal compound used in the biomedical industry for its anti-inflammatory and antimitotic properties. It plays a crucial role in studying gout and acute flares by inhibiting microtubule polymerization and reducing neutrophil infiltration. Synonyms: (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-3-yl b-D-glucopyranosiduronic acid. CAS No. 913079-71-7. Molecular formula: C27H31NO12. Mole weight: 561.53.
3-Demethylthiocolchicine is a colchicine (HY-16569) analog with broad-spectrum antitumor activity. 3-Demethylthiocolchicine has the same effects and activities as colchicine in blocking casein-induced amyloidosis, microtubule binding, and anti-inflammatory effects, with significantly lower toxicity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87424-25-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W355463.
3-Demethyl thiocolchicine
3-Demethyl thiocolchicine. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; 2-Demethylthio-colchicine; 3-De methyl thiocolchicine. Grades: Highly Purified. CAS No. 87424-25-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H23NO5S. US Biological Life Sciences.
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3-Demethyl Thiocolchicine
3-Demethyl Thiocolchicine is a Thiocolchicine metabolite, used in therapy as an antitunor, antiinflammatory and immunosuppressive agent. Synonyms: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; 2-Demethylthio-colchicine; 3-Demethylthiocolchicine; 3-Desmethylthiocolchicine; 3-O-Demethylthiocolchicine; NSC 361792. Grades: > 95%. CAS No. 87424-25-7. Molecular formula: C21H23NO5S. Mole weight: 401.48.
3-Demethyl Thiocolchicine-d3
A Thiocolchicine metabolite, used in therapy as an antitunor, antiinflammatory and immunosuppressive agent. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide-d3; 2-Demethylthio-colchicine-d3; 3-Demethylthiocolchicine-d3; 3-Des methyl thiocolchicine-d3; 3-O-Demethylthiocolchicine-d3; NSC 361792-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Colchiceine
A metabolite of Colchicine. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-10-hydroxy-1,2,3,-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; O10-Demethylcolchicine; NSC 33411. Grades: Highly Purified. CAS No. 477-27-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Colchicine EP impurity D
Colchicoside is a significantly toxic Colchicine analog with no anti-inflammatory properties. Synonyms: (S)-N-[3-(b-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; N-[(7S)-3-(b-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; 3-Demethylcolchicine glucoside. Grades: > 95%. CAS No. 477-29-2. Molecular formula: C27H33NO11. Mole weight: 547.55.
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