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Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule , has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis [1]. Deoxypodophyllotoxin induces cell autophagy and apoptosis [2]. Deoxypodophyllotoxin evokes increase of intracellular Ca 2+ concentrations in DRG neurons [3]. Uses: Scientific research. Group: Natural products. CAS No. 19186-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2500.
Deoxypodophyllotoxin
Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis. Deoxypodophyllotoxin induces cell autophagy and apoptosis. Deoxypodophyllotoxin evokes increase of intracellular Ca2+ concentrations in DRG neurons. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 19186-35-7. Molecular formula: C22H22O7. Mole weight: 398.4. Purity: 0.98. IUPACName: (5R,5aR,8aR)-5-(3,4,5-trimethoxyphenyl)-5a,8,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one. Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O. Product ID: ACM19186357. Alfa Chemistry ISO 9001:2015 Certified.
This cytochrome P450 enzyme, characterized from the plant Sinopodophyllum hexandrum, produces the direct precursor to etoposide, a potent anticancer drug. It can also act on (-)-deoxypodophyllotoxin with lower efficiency. Group: Enzymes. Synonyms: CYP82D61 (gene name). Enzyme Commission Number: EC 1.14.13.214. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0816; (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase; EC 1.14.13.214; CYP82D61 (gene name). Cat No: EXWM-0816.
4-Deoxypodophyllotoxin
4-Deoxypodophyllotoxin. Group: Biochemicals. Alternative Names: AS 2-3; Anthricin; Deoxypodophyllotoxin; Desoxypodophyllotoxin; Silicicolin; (-)-Anthricin; (-)-Deoxypodophyllotoxin; (-)-Desoxypodophyllotoxin. Grades: Highly Purified. CAS No. 19186-35-7. Pack Sizes: 100mg. Molecular Formula: C22H22O7, Molecular Weight: 398.41. US Biological Life Sciences.
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(-)-deoxypodophyllotoxin synthase
The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. It catalyses the closure of the central six-membered ring in the aryltetralin scaffold. Group: Enzymes. Synonyms: 2-ODD (gene name). Enzyme Commission Number: EC 1.14.11.50. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0669; (-)-deoxypodophyllotoxin synthase; EC 1.14.11.50; 2-ODD (gene name). Cat No: EXWM-0669.
3-Bromobenzoic Acid
3-Bromobenzoic Acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 585-76-2. Pack Sizes: 1g, 10 g. Molecular Formula: C7H5BrO2. US Biological Life Sciences.
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4'-De methyl desoxypodophyllotoxin
4'-De methyl desoxypodophyllotoxin. Group: Biochemicals. Alternative Names: [5R-(5α,5a β, 8aα)]-5, 8, 8a, 9-Tetrahydro-5-(4-hydroxy-3, 5-dimethoxyphenyl)-furo[3', 4':6, 7]naphtho[2, 3-d]-1, 3-dioxol-6(5aH)-one; Podophyllotoxin, 4'-O-demethyl-4-deoxy-(7CI,8CI); 4-De methyl deoxypodophyllotoxin; 4'-De methyl deoxypodophyllotoxin; A 80198; DDPT. Grades: Highly Purified. CAS No. 3590-93-0. Pack Sizes: 50mg. Molecular Formula: C22H22O7, Molecular Weight: 398.41. US Biological Life Sciences.
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