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This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in pentose phosphate pathway. Group: Enzymes. Synonyms: phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.4. CAS No. 9026-97-5. DERA. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4875; deoxyribose-phosphate aldolase; EC 4.1.2.4; 9026-97-5; phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase. Cat No: EXWM-4875.
2-Deoxyribose 5-phosphate Aldolase, E. coli K12, recombinant K12 from E. coli
2-Deoxyribose 5-phosphate Aldolase from E. coli, Recombinant
Deoxyriboaldolase catalyzes the condensation of acetaldehyde and glyceraldehyde 3-phosphate to 2-deoxyribose 5-phosphate. This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in pentose phosphate pathway. Group: Enzymes. Synonyms: 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase; deoxyribose-phosphate aldolase; EC 4.1.2.4; DERA; 9026-97-5. Enzyme Commission Number: EC 4.1.2.4. CAS No. 9026-97-5. DERA. Activity: >2 U/mg. Storage: Store at -20°C. Source: E. coli K12. Species: E. coli. 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase; deoxyribose-phosphate aldolase; EC 4.1.2.4; DERA; 9026-97-5. Cat No: NATE-0794.
2-Deoxyribose 5-phosphate disodium salt
2-Deoxyribose 5-phosphate sodium salt (CAS# 102916-66-5) is used in the chemoenzymatic preparation of deoxyribonucleosides as starting materials in the enzymic preparation of natural and modified purine and pyrimidine nucleosides. It is used in the synthesis of 2-Oxo-3-deoxy-6-phosphogluconate (ODPG) aldolase which is useful as a catalyst in organic synthesis. Synonyms: D-erythro-Pentose, 2-deoxy-, 5-(dihydrogen phosphate), sodium salt (1:2); D-erythro-Pentose, 2-deoxy-, 5-(dihydrogen phosphate), disodium salt; 2-Deoxy-D-ribose 5-phosphate disodium salt; 2-Deoxyribose 5-phosphate sodium salt. CAS No. 102916-66-5. Molecular formula: C5H9Na2O7P. Mole weight: 258.07.
5-Iodo-2-pyrimidinone-2-deoxyribose
5-Iodo-2-pyrimidinone-2-deoxyribose. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-deoxy-beta-ribofuranosyl)-5-iodo-2-pyrimidinone;5-Iodo-2-pyrimidinone-2-deoxyribose;IPdR;Ropidoxuridine. Product Category: Heterocyclic Organic Compound. CAS No. 93265-81-7. Molecular formula: C9H11IN2O4. Mole weight: 338.1. Product ID: ACM93265817. Alfa Chemistry ISO 9001:2015 Certified.
5-Nitro-1-indolyl-2'-deoxyribose-5'-Triphosphate
5-Nitro-1-indolyl-2'-deoxyribose-5'-Triphosphate, a modified nucleotide, finds application in research work related to DNA sequencing and detection. Notably, it also interacts with polymerases and kinases, making it of interest in studying enzyme kinetics and DNA repair. Its fluorescent nature enables the detection of cancer cells and virus particles, presenting a promising avenue of investigation and diagnosis. As such, the compound is a valuable tool in various scientific fields. Synonyms: 5-Nitro-1-Indolyl-drTP. Grade: ≥90% by AX-HPLC. Molecular formula: C13H17N2O14P3. Mole weight: 518.20.
5-O-DMTr-1-Deoxyribose-3-O-TBDMS-2-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite is a specialized phosphoramidite used in the synthesis of oligonucleotides, offering a combination of protective groups and functional modifications. It features a 5'-O-dimethoxytrityl (DMTr) group, which protects the 5'-hydroxyl group during oligonucleotide synthesis, allowing for selective deprotection and chain elongation. The 3'-O-tert-butyldimethylsilyl (TBDMS) group is a protecting group for the 3'-hydroxyl, preventing premature reactions during synthesis. This phosphoramidite is commonly used in oligonucleotide synthesis for applications that require specific structural modifications, such as enhanced stability, resistance to degradation, or customization for therapeutic uses, including gene editing, RNA interference, or antisense therapies. Synonyms: 5'-O-DMTr-1-Deoxyribose-3'-O-TBDMS-2'-CE-phosphoramidite; DMT-1-Deoxyribose-3'-O-TBDMS-2'-CE-phosphoramidite. Grade: ≥95%. Molecular formula: C41H59N2O7PSi. Mole weight: 750.99.
1-Ethynyl-dSpacer CE Phosphoramidite
1-Ethynyl-dSpacer CE Phosphoramidite: An Indispensable Reagent in DNA Synthesis for Studying Protein-DNA Interactions and Targeting Disease States. This vital reagent facilitates phosphorothioate-modified oligonucleotide synthesis, which is crucial in elucidating protein-DNA interactions. Additionally, it is pivotal in the construction of antisense oligonucleotides, enabling the suppression of diverse disease indications, including cancer and viral infections. Synonyms: 5'-O-Dimethoxytrityl-1'-ethynyl-2'-deoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C37H45N2O6P. Mole weight: 644.74.
(1R,2S,4R)-4-Amino-2-hydroxy-cyclopentanemethanol Hydrochloride can be used as a reagent/reactant for stereoselective synthesis and antiviral activity of carbocyclic nucleoside analog of pentyl phenyl furopyrimidine deoxyribose via stereoselective hydroboration, heterocyclization and Sonogashira coupling from Vince lactam (1). (1R,2S,4R)-4-Amino-2-hydroxy-cyclopentanemethanol Hydrochloride can also be obtained from (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one (A795205) which is an Abacavir intermediate used in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues (2). Group: Biochemicals. Grades: Highly Purified. CAS No. 155750-92-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H13NO2 HCl, Molecular Weight: 131.173645999999. US Biological Life Sciences.
Worldwide
2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2
2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2, is an intermediate in the synthesis of 8-Oxo-2'-deoxyguanosine-13C,15N2. A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. It can induce differentiation of Friend murine erythroleukemia cells in vitro. Synonyms: 2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2; 2-Amino-N6-methoxy-2'-deoxyadenosine-13C,15N2; DK-13C,15N2; K-2'-Deoxyribose-13C,15N2; K-Nucleoside (dK)-13C,15N2. Molecular formula: C10[13C]H16N4[15N]2O4. Mole weight: 299.26.
2- (Benzyloxy) acetaldehyde
Acceptor; engineering of 2-deoxyribose 5-phosphate aldolase variants for enzymic preparation of β-ketols. Group: Biochemicals. Alternative Names: 2- (Phenylmethoxy) acetaldehyde; α - (Benzyloxy) acetaldehyde; (Benzyloxy) acetaldehyde; 2-(Benzyloxy)ethanal; (Phenylmethoxy) acetaldehyde. Grades: Highly Purified. CAS No. 60656-87-3. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
2'-Deoxy-5'-O-trityluridine
2'-Deoxy-5'-O-trityluridine, an organic chemical compound, finds its use in the synthesis of oligonucleotides. Researchers have reported its successful use as a protecting group on the 5'-OH of deoxyribose when synthesizing DNA. Additionally, its potential in combatting herpes simplex virus type 1 has attracted attention. Synonyms: 5'-O-Triphenylmethyl-2'-deoxyuridine; 5'-O-Trityl-2'-deoxyuridine; Uridine, 2'-deoxy-5'-O-(triphenylmethyl)-; 1-((2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; NSC 375393. Grade: ≥95%. CAS No. 14270-73-6. Molecular formula: C28H26N2O5. Mole weight: 470.52.
2'-Deoxyadenosine
2'-Deoxyadenosine is a nucleoside utilized extensively in the biomedical sector for research objectives, exhibiting multifarious applications. Primarily, it finding utility in the synthesis of oligonucleotides and DNA fragments, thereby bolstering the advancement of genetic studies and molecular biology research. Uses: Antiviral agents. Synonyms: Adenosine, 2'-deoxy-; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine; 9H-Purin-6-amine, 9-(2-deoxy-β-D-erythro-pentofuranosyl)-; 9H-Purin-6-amine, 9-(2-deoxy-β-D-ribofuranosyl)-; Adenine deoxyribonucleoside; Adenine deoxyribose; Adenyldeoxyriboside; dA; Deoxyadenosine; Desoxyadenosine; NQZ-035; NSC 141848; NSC 143510; NSC 83258; β-D-erythro-Pentofuranoside, adenine-9 2-deoxy-; β-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1,2-dideoxy-. Grade: 98%. CAS No. 958-09-8. Molecular formula: C10H13N5O3. Mole weight: 251.24.
2'-Deoxyadenosine
2'-Deoxyadenosine is a purine nucleoside composed of Adenine (HY-B0152) and 2'-deoxyribose. 2'-Deoxyadenosine activates Caspase-3 and promotes Apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 958-09-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W040329.
2'-Deoxyadenosine-1-[13C] hydrate
2'-Deoxyadenosine-1-[13C] hydrate is the labelled analogue of 2'-Deoxyadenosine Monohydrate, which is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as an anti-hepatitis C virus agent. Synonyms: 2'-Deoxyadenosine hydrate (deoxyribose-1-13C); 2'-Deoxyadenosine-1'-13C Monohydrate; Adenine deoxyriboside-1'-13C hydrate; 2'-Deoxy-β-D-adenosine-1'-13C Monohydrate; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine-1'-13C Hydrate; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy-β-D-ribofuranose-1'-13C Hydrate; 2-Deoxyadenine-9-β-D-erythro-pento-furanoside-1'-13C Hydrate. Grade: 98%; 99% atom 13C. CAS No. 446276-63-7. Molecular formula: C9[13C]H13N5O3.H2O. Mole weight: 270.26.
Used to synthesize labelled 5'-modified 2'-deoxyadenosine analogs as anti-hepatitis C virus preparations. It is also a derivative of nucleoside adenosine. Synonyms: 2'-Deoxy-β-D-adenosine-13C2,15N; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine-13C2,15N; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine-13C2,15N; Adenine Deoxyribonucleoside-13C2,15N; Adenine Deoxyribose-13C2,15N; Adenyldeoxyriboside-13C2,15N; Deoxyadenosine-13C2,15N; Desoxyadenosine-13C2,15N; NSC 141848-13C2,15N; NSC 143510-13C2,15N; NSC 83258-13C2,15N; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy-β-D-ribofuranose-13C2,15N; 2-Deoxyadenine-9-β-D-erythro-pento-furanoside-13C2,15N. Molecular formula: C8[13C]2H13N4[15N]O3. Mole weight: 254.22.
2'-Deoxyadenosine-[13C5] Monohydrate
2'-Deoxyadenosine-[13C5] Monohydrate is the labelled analogue of 2'-Deoxyadenosine Monohydrate, which is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents. Uses: Used in the synthesis of labelled 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis c virus agents. Synonyms: 2'-Deoxy-β-D-adenosine-13C5 Monohydrate; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine-13C5; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine-13C5 Hydrate; Adenine Deoxyribonucleoside-13C5 Hydrate; Adenine Deoxyribose-13C5 Hydrate; Adenyldeoxyriboside-13C5 Hydrate; Deoxyadenosine-13C5 Hydrate; Desoxyadenosine-13C5 Hydrate; NSC 141848; NSC 143510; NSC 83258; dA; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy-β-D-ribofuranose-13C5 Hydrate; 2-Deoxyadenine-9-β-D-erythro-pento-furanoside-13C5 Hydrate. Grade: 98%; 98.7% atom 13C. CAS No. 478510-79-1. Molecular formula: C5[13C]5H15N5O4. Mole weight: 274.22.
2'-Deoxyadenosine-15N1
2'-Deoxyadenosine-15N1 is an intermediate in the synthesis of 8-Oxo-2'-deoxyguanosine-13C,15N2. A Marker compound indicating DNA damage related to mutagenesis and canceration. It can induce the differentiation of Friend mouse red leukemia cells in vitro. Synonyms: 12'-Deoxyadenosine-15N1; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine-15N1; 9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine-15N1; 9-(2-deoxy-β-D-ribofuranosyl)-9H-Purin-6-amine-15N1; Adenine Deoxyribonucleoside-15N1; Adenine Deoxyribose-15N1; Adenyldeoxyriboside-15N1; Deoxyadenosine-15N1; Desoxyadenosine-15N1; NSC 141848-15N1; NSC 143510-15N1; NSC 83258-15N1; dA-15N1; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy-β-D-Ribofuranose-15N1; Adenine-9 2-Deoxy-β-D-erythro-pentofuranoside-15N1. Molecular formula: C10H13N4[15N]O3. Mole weight: 252.24.
2'-Deoxyadenosine Monohydrate
2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents. Synonyms: 2'-Deoxy-β-D-adenosine Monohydrate; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine Hydrate; Adenine Deoxyribonucleoside Hydrate; Adenine Deoxyribose Hydrate; Adenyldeoxyriboside Hydrate; Deoxyadenosine Hydrate; Desoxyadenosine Hydrate; NSC 141848; NSC 143510; NSC 83258; dA; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy-β-D-ribofuranose Hydrate; 2-Deoxyadenine-9-β-D-erythro-pento-furanoside Hydrate. Grade: 98 %. CAS No. 16373-93-6. Molecular formula: C10H15N5O4. Mole weight: 269.26.
2-Deoxyadenosine Monohydrate (2'-dA·H2O)
Used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents. Group: Biochemicals. Alternative Names: 2'-dA·H2O; 9-(2-Deoxy-b-D-ribofuranosyl)adenine; 2'-Deoxy-D-adenosine; (2R, 3S, 5R) -5- (6-Amino-9H-purin-9-yl) -2- (hydroxymethyl) tetrahydrofuran-3-ol; 9-(2-Deoxy- β -D-erythro-pentofuranosyl) adenine; 9-(2-Deoxy- β-D-erythro-pentofuranosyl)-9H-purin-6-amine; Adenine Deoxyribonucleoside; Adenine Deoxyribose; Adenyldeoxyriboside; Deoxyadenosine; Desoxyadenosine; NSC 141848; NSC 143510; NSC 83258; dA; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy- β-D-ribofuranose; 2-Deoxyadenine-9- β-D-erythro-pento-furanoside. Grades: Molecular Biology Grade. CAS No. 16373-93-6. Pack Sizes: 5g, 10g, 25g, 50g. Molecular Formula: C10H13N5O3·H2O, Molecular Weight: 269.24. US Biological Life Sciences.
Worldwide
2'-Deoxycytidine
2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine ( Brdu ). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Deoxycytidine; Cytosine deoxyriboside; Deoxyribose cytidine. CAS No. 951-77-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-D0184.
2'-Deoxycytidine-[2'-13C] Monohydrate
2-Deoxycytidine-[2-13C] Hydrate is the labelled Hydrate of 2-Deoxycytidine, which is a deoxyribonucleoside as an Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity. Synonyms: 2-Deoxycytidine H2O (deoxyribose-2-13C); 2'-Deoxycytidine-13C Hydrate; 2'-Deoxycytidine-2'-13C Monohydrate; [2'-13C]2'-deoxycytidine 1-hydrate; 1-(2-Deoxy-β-D-ribofuranosyl)cytosine-13C Hydrate; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone-13C Hydrate; Cytosine Deoxyribonucleoside-13C Hydrate. Grade: ≥90%; ≥99% atom 13C. CAS No. 478511-23-8. Molecular formula: C8[13C]H15N3O5. Mole weight: 246.23.
2'-Deoxy Cytidine-[2',2'-d2]
2'-Deoxy Cytidine-[2',2'-d2] is the labelled analogue of 2'-Deoxy Cytidine, which is a deoxyribonucleoside used as an Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity. Synonyms: 2'-Deoxy Cytidine-2',2'-d2; 1-(2-Deoxy-β-D-ribofuranosyl)cytosine-d2; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone-d2; Cytosine Deoxyribonucleoside-d2; Cytosine Deoxyriboside-d2; Deoxycytidine-d2; Deoxyribose Cytidine-d2. CAS No. 114218-03-0. Molecular formula: C9H11D2N3O4. Mole weight: 229.23.
2'-Deoxy Cytidine-[5,6-d2]
2'-Deoxy Cytidine-[5,6-d2] is the labelled analogue of 2'-Deoxy Cytidine, which is a deoxyribonucleoside used as an Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity. Synonyms: 2'-Deoxy Cytidine-5,6-d2; 1-(2-Deoxy-β-D-ribofuranosyl)cytosine-d2; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone-d2; Cytosine Deoxyribonucleoside-d2; Cytosine Deoxyriboside-d2; Deoxycytidine-d2; Deoxyribose Cytidine-d2. Grade: ≥90%. CAS No. 1186526-91-9. Molecular formula: C9H11D2N3O4. Mole weight: 229.23.
2'-Deoxy Cytidine-[5-d]
2'-Deoxy Cytidine-[5-d] is the labelled analogue of 2'-Deoxy Cytidine, which is a deoxyribonucleoside used as an Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity. Synonyms: 2'-Deoxy Cytidine-5-d1; 1-(2-Deoxy-β-D-ribofuranosyl)cytosine-d1; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone-d1; Cytosine Deoxyribonucleoside-d1; Cytosine Deoxyriboside-d1; Deoxycytidine-d1; Deoxyribose Cytidine-d1. CAS No. 25352-61-8. Molecular formula: C9H12DN3O4. Mole weight: 228.22.
2'-Deoxycytidine hydrochloride
2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. Uses: Scientific research. Group: Natural products. Alternative Names: 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251. CAS No. 3992-42-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-17564.
2'-Deoxycytidine hydrochloride
2'-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. Synonyms: 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251; NSC83251; NSC-83251. Grade: ≥ 97%. CAS No. 3992-42-5. Molecular formula: C9H13N3O4.HCl. Mole weight: 263.68.
2-Deoxy-d-ribose
2-Deoxy-d-ribose. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Deoxyribose. Appearance: Solid. CAS No. 533-67-5. Molecular formula: C5H10O4. Mole weight: 134.13. Purity: 0.98. IUPACName: (3S,4R)-3,4,5-Trihydroxypentanal. Canonical SMILES: C(C=O)C(C(CO)O)O. Density: 1.059 g/cm³. Product ID: ACM533675. Alfa Chemistry ISO 9001:2015 Certified.
2-Deoxy-D-ribose
2-Deoxy-D-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Uses: A monosaccharide and a component of dna. Synonyms: 2-Deoxy-D-erythro-pentose; 2-Deoxy-D-arabinose; D-(-)-2-Deoxyribose; Deoxyribose; Thyminose. Grade: > 95 %. CAS No. 533-67-5. Molecular formula: C5H10O4. Mole weight: 134.13.
2-Deoxy-D-ribose-1-13C
2-Deoxy-D-ribose-1-13C. Group: Biochemicals. Alternative Names: 2-Deoxy-D-erythro-pentose-1-13C; 2-Deoxy-D-arabinose-1-13C; D-(-)-2-Deoxyribose-1-13C. Grades: Highly Purified. CAS No. 478511-57-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
2-Deoxy-D-ribose-1-[13C]
2-Deoxy-D-ribose-1-[13C] is the labelled analogue of 2-Deoxy-D-ribose, which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Synonyms: 2-Deoxyribose-1-13C; 2-Deoxy-D-erythro-pentose-1-13C; 2-Deoxy-D-arabinose-1-13C; D-(-)-2-Deoxyribose-1-13C; Deoxyribose-1-13C; Thyminose-1-13C. Grade: 98%; 99% atom 13C. CAS No. 478511-57-8. Molecular formula: C4[13C]H10O4. Mole weight: 135.12.
2-Deoxy-D-ribose-13C5
2-Deoxy-D-ribose-13C5. Group: Biochemicals. Alternative Names: 2-Deoxy-D-erythro-pentose-13C5; 2-Deoxy-D-arabinose-13C5; D-(-)-2-Deoxyribose-13C5. Grades: Highly Purified. CAS No. 266998-43-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
2-Deoxy-D-ribose-[13C5]
2-Deoxy-D-ribose-[13C5] is the labelled analogue of 2-Deoxy-D-ribose, which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Synonyms: 2-Deoxy-D-erythro-pentose-13C5; 2-Deoxy-D-arabinose-13C5; D-(-)-2-Deoxyribose-13C5; 2-deoxy-D-[UL-13C5]ribose. CAS No. 266998-43-0. Molecular formula: [13C]5H10O4. Mole weight: 139.09.
2-Deoxy-D-ribose-2-13C
2-Deoxy-D-ribose-2-13C. Group: Biochemicals. Alternative Names: 2-Deoxy-D-erythro-pentose-2-13C; 2-Deoxy-D-arabinose-2-13C; D-(-)-2-Deoxyribose-2-13C. Grades: Highly Purified. CAS No. 478511-60-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
2-Deoxy-D-ribose-[5-13C]
2-Deoxy-D-ribose-[5-13C] is the labelled analogue of 2-Deoxy-D-ribose, which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Synonyms: 2-Deoxy-D-erythro-pentose-5-13C; 2-Deoxy-D-arabinose-5-13C; D-(-)-2-Deoxyribose-5-13C; Deoxyribose-5-13C; Thyminose-5-13Cl; 2-deoxy-D-[5-13C]ribose. CAS No. 159838-86-5. Molecular formula: C4[13C]H10O4. Mole weight: 135.12.
2-Deoxy-D-ribose-5-13C
2-Deoxy-D-ribose-5-13C. Group: Biochemicals. Alternative Names: 2-Deoxy-D-erythro-pentose-5-13C; 2-Deoxy-D-arabinose-5-13C; D-(-)-2-Deoxyribose-5-13C. Grades: Highly Purified. CAS No. 159838-86-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
2-Deoxy-D-ribose-5,5-[d2]
2-Deoxy-D-ribose-5,5-[d2] is the labelled analogue of 2-Deoxy-D-ribose, which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Synonyms: 2-Deoxy-D-ribose-5,5-d2; 2-Deoxy-D-erythro-pentose-5,5'-d2; 2-Deoxy-D-arabinose-5,5'-d2; D-(-)-2-Deoxyribose-5,5'-d2; Deoxyribose-5,5'-d2; Thyminose-5,5'-d2; 2-deoxy-D-[5,5'-2H2]erythro-pentose. Grade: ≥98%; 98% atom D. CAS No. 478511-68-1. Molecular formula: C5H8D2O4. Mole weight: 136.14.
2-Deoxy-D-ribose-5,5'-d2
2-Deoxy-D-ribose-5,5'-d2. Group: Biochemicals. Alternative Names: 2-Deoxy-D-erythro-pentose-5,5'-d2; 2-Deoxy-D-arabinose-5,5'-d2; D-(-)-2-Deoxyribose-5,5'-d2; Deoxyribose-5,5'-d2; Thyminose-5,5'-d2. Grades: Highly Purified. CAS No. 478511-68-1. Pack Sizes: 2.5mg. Molecular Formula: C5H8D2O4, Molecular Weight: 136.139999999999. US Biological Life Sciences.
Worldwide
2'-Deoxyguanosine
2(acute)-Deoxyguanosine is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). It is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. It is useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides. Synonyms: Deoxyguanosine; Guanine deoxyriboside; 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 9H-Purin-6-ol, 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)guanine. Grade: ≥95%. CAS No. 961-07-9. Molecular formula: C10H13N5O4. Mole weight: 267.24.
2'-Deoxyguanosine monohydrate
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1 O 2 , the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 312693-72-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-D0185.
2-Deoxy-L-ribose
2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Uses: 2-deoxy-l-ribose is an isomer of 2-deoxy-d-ribose which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Synonyms: 2-Deoxy-L-erythro-pentose; L-2-Deoxyribose; L-erythro-Pentose, 2-deoxy-; L-threo-2-deoxy-pentose; L-Deoxyribose. Grade: ≥98% by GC. CAS No. 18546-37-7. Molecular formula: C5H10O4. Mole weight: 134.13.
2-Deoxy-L-ribose 98+%
2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Group: Biochemicals. Alternative Names: 2-Deoxy-L-erythro-pentose; L-2-Deoxyribose; L-erythropentofuranose; L-erythro-Pentose, 2-deoxy; (3R,4S)-3,4,5-trihydroxypentanal; L-Deoxyribose; (4R,5S)-5-(hydroxymethyl)oxolane-2,4-diol. Grades: Reagent Grade. CAS No. 18546-37-7. Pack Sizes: 1g, 5g, 25g. Molecular Formula: C?H??O?, Molecular Weight: 134.13. US Biological Life Sciences.
Worldwide
2'-DeoxypseudoUridine
2'-DeoxypseudoUridine belongs to the C-glycosides that linked by C-C bond rather than usual C1-N1 bond found in uridine. Especially, glycosidic bond of 2'-deoxypseudoUridine is that C-C bond between C5 of uracil and C1 of the deoxyribose sugar. 2'-DeoxypseudoUridine can be served as one of the modified deoxyribonucleosides to participate in the synthesis of DNA oligonucleotides, resulting in modified DNA. Synonyms: Deoxypseudouridine; 2,4(1H,3H)-Pyrimidinedione, 5-(2-deoxy-b-D-erythro-pentofuranosyl)-; 2'-Deoxypseudo-D-uridine; (1R)-1,4-Anhydro-2-desoxy-1-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-D-erythro-pentitol. Grade: ≥97%. CAS No. 39967-60-7. Molecular formula: C9H12N2O5. Mole weight: 228.2.
2'-Deoxyuridine
It is a derivative of uridine that is used as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Uses: Antimetabolites. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil; Deoxyribose Uracil; Deoxyuridine; NSC 23615; Uracil Deoxyriboside; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-beta-D-ribofuranosyl)uracil. Grade: ≥95%. CAS No. 951-78-0. Molecular formula: C9H12N2O5. Mole weight: 228.20.
2'-deoxyuridine-[1'-13C]
2'-deoxyuridine-[1'-13C] is the isotope labelled analogue 2'-Deoxyuridine, which is a uridine derivative as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil-1'-13C; 2'-Desoxyuridine; Deoxyribose Uracil-1'-13C; Deoxyuridine-1'-13C; NSC 23615-1'-13C; Uracil Deoxyriboside-1'-13C. CAS No. 478510-85-9. Molecular formula: C8[13C]H12N2O5. Mole weight: 229.19.
2'-Deoxyuridine-1-13C
2'-Deoxyuridine-1-13C. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-D-erythro-pentofuranosyl)uracil-1-13C; 2'-Desoxyuridine; Deoxyribose Uracil-1-13C; Deoxyuridine-1-13C; NSC 23615-1-13C; Uracil Deoxyriboside-1-13C. Grades: Highly Purified. CAS No. 478510-85-9. Pack Sizes: 1mg. Molecular Formula: C813CH12N2O5, Molecular Weight: 229.2. US Biological Life Sciences.
Worldwide
2'-Deoxyuridine-1',2',3',4',5'-13C5
2'-Deoxyuridine-1',2',3',4',5'-13C5. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-D-erythro-pentofuranosyl)uracil-1',2',3',4',5'-13C5; 2'-Desoxyuridine; Deoxyribose Uracil-1',2',3',4',5'-13C5; Deoxyuridine-1',2',3',4',5'-13C5; NSC 23615-1',2',3',4',5'-13C5; Uracil Deoxyriboside-1',2',3',4',5'-13C5. Grades: Highly Purified. CAS No. 478510-94-0. Pack Sizes: 1mg. Molecular Formula: C413C5H12N2O5, Molecular Weight: 233.17. US Biological Life Sciences.
Worldwide
2'-Deoxyuridine-[13C,15N2]
2'-Deoxyuridine-[13C,15N2] is the labelled analogue of 2'-Deoxyuridine, which is a uridine derivative used as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Uses: An uridine labelled derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Synonyms: 2'-Deoxyuridine-13C,15N2; 2-Deoxyuridine-2-13C,1,3-15N2; 2'-Deoxy-uridine-2-13C-1,3-15N2; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil-13C,15N2; Deoxyribose Uracil-13C,15N2; NSC 23615-13C,15N2. Grade: ≥98%; 99% atom 13C; 99% atom 15N. CAS No. 369656-76-8. Molecular formula: C8[13C]H12[15N]2O5. Mole weight: 231.18.
2'-deoxyuridine-[2'-13C] is the isotope labelled analogue 2'-Deoxyuridine, which is a uridine derivative as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil-2'-13C; 2'-Desoxyuridine; Deoxyribose Uracil-2'-13C; Deoxyuridine-2'-13C; NSC 23615-2'-13C; Uracil Deoxyriboside-2'-13C. CAS No. 478510-87-1. Molecular formula: C8[13C]H12N2O5. Mole weight: 229.19.
2'-Deoxyuridine-2'-13C
2'-Deoxyuridine-2'-13C. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-D-erythro-pentofuranosyl)uracil-2'-13C; 2'-Desoxyuridine; Deoxyribose Uracil-2'-13C; Deoxyuridine-2'-13C; NSC 23615-2'-13C; Uracil Deoxyriboside-2'-13C. Grades: Highly Purified. CAS No. 478510-87-1. Pack Sizes: 1mg. Molecular Formula: C813CH12N2O5, Molecular Weight: 229.2. US Biological Life Sciences.
Worldwide
2'-Deoxyuridine-[3'-13C]
2'-Deoxyuridine-[3'-13C] is the labelled analogue of 2'-Deoxyuridine, which is a uridine derivative used as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Synonyms: 2'-Deoxyuridine-3'-13C; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil-3'-13C; Deoxyribose Uracil-3'-13C; Deoxyuridine-3'-13C; NSC 23615-3'-13C; Uracil Deoxyriboside-3'-13C. Grade: 95%; ≥95% atom 13C. CAS No. 478510-89-3. Molecular formula: C8[13C]H12N2O5. Mole weight: 229.20.
2'-Deoxyuridine-3'-13C
2'-Deoxyuridine-3'-13C. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-D-erythro-pentofuranosyl)uracil-3'-13C; 2'-Desoxyuridine; Deoxyribose Uracil-3'-13C; Deoxyuridine-3'-13C; NSC 23615-3'-13C; Uracil Deoxyriboside-3'-13C. Grades: Highly Purified. CAS No. 478510-89-3. Pack Sizes: 1mg. Molecular Formula: C813CH11N2O5, Molecular Weight: 228.19. US Biological Life Sciences.
Worldwide
2'-Deoxyuridine-[5'-13C]
2'-Deoxyuridine-[5'-13C] is the labelled analogue of 2'-Deoxyuridine, which is a uridine derivative used as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Synonyms: 2'-Deoxyuridine-5'-13C; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil-5'-13C; Deoxyribose Uracil-5'-13C; Deoxyuridine-5'-13C; NSC 23615-5'-13C; Uracil Deoxyriboside-5'-13C; Uridine-5'-13C, 2'-deoxy-. Grade: ≥90%; ≥98% atom 13C. CAS No. 478510-91-7. Molecular formula: C8[13C]H12N2O5. Mole weight: 229.20.
2'-Deoxyuridine-5'-13C
2'-Deoxyuridine-5'-13C. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-D-erythro-pentofuranosyl)uracil-5'-13C; 2'-Desoxyuridine; Deoxyribose Uracil-5'-13C; Deoxyuridine-5'-13C; NSC 23615-5'-13C; Uracil Deoxyriboside-5'-13C. Grades: Highly Purified. CAS No. 478510-91-7. Pack Sizes: 1mg. Molecular Formula: C813CH11N2O5, Molecular Weight: 228.19. US Biological Life Sciences.
Worldwide
2'-Deoxyuridine-[5',5''-d2]
2'-Deoxyuridine-[5',5''-d2] is the labelled analogue of 2'-Deoxyuridine, which is a uridine derivative used as a therapeutic agent for treating allergy, cancer, infection and autoimmune disease. Synonyms: 2'-Deoxyuridine-5',5''-D2; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil-5',5''-d2; Deoxyribose Uracil-5',5''-d2; Deoxyuridine-5',5''-d2; NSC 23615-5',5''-d2; Uracil Deoxyriboside-5',5''-d2; Uridine-5',5'-d2, 2'-deoxy-. Grade: ≥90%; ≥95% atom D. CAS No. 478511-30-7. Molecular formula: C9H10D2N2O5. Mole weight: 230.22.
2'-Deoxyuridine-5',5''-d2
2'-Deoxyuridine-5',5''-d2. Group: Biochemicals. Alternative Names: 1-(2-Deoxy- β-D-erythro-pentofuranosyl)uracil-5',5''-d2; 2'-Desoxyuridine; Deoxyribose Uracil-5',5''-d2; Deoxyuridine-1-d; NSC 23615-5',5''-d2; Uracil Deoxyriboside-5',5''-d2. Grades: Highly Purified. CAS No. 478511-30-7. Pack Sizes: 1mg. Molecular Formula: C9H10D2N2O5, Molecular Weight: 230.22. US Biological Life Sciences.
3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-D-ribofuranose is an essential compound in synthesizing highly efficacious antiviral medications. Its unconventional molecular configuration, characterized by a fluorinated ribose unit, manifests extraordinary antiviral properties against a wide range of viruses, including the notorious HIV and HCV. Synonyms: 2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate 3,5-Di-O-benzoyl-2,2-difluoro-2-deoxyribose. CAS No. 143157-22-6. Molecular formula: C19H16F2O6. Mole weight: 378.32.
3'-O-Acetyl-4'-thio-2'-deoxy-beta-D-uridine
3'-O-Acetyl-4'-thio-2'-deoxy-β-D-uridine is a modified uridine nucleoside where the 3' hydroxyl group is protected with an acetyl group, and the 4' position of the sugar is modified by replacing the oxygen atom with a sulfur atom (creating a thionucleoside). Additionally, the sugar is 2'-deoxyribose, which is characteristic of DNA nucleosides. This compound is likely used in specialized nucleic acid synthesis, such as creating modified RNA or DNA analogs. The protective groups and sulfur substitution can influence the reactivity, stability, and incorporation of this nucleoside in oligonucleotide synthesis, potentially providing insights into biochemical interactions or therapeutic applications. Synonyms: 1-[2-Deoxy-3-o-acetyl-4-thio-beta-d-ribofuranosyl]uracil; Uridine, 2'-deoxy-4'-thio-, 3'-acetate; 3'-O-Acetyl-2'-Deoxy-4'-thiouridine; (2R,3S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrothiophen-3-yl acetate. Grade: ≥95%. CAS No. 667882-69-1. Molecular formula: C11H14N2O5S. Mole weight: 286.31.
3'-O-Acetyl-N2-isobutyryl-4'-thio-2'-deoxy-β-D-guanosine is a chemically modified nucleoside with multiple functional group modifications. The 3'-hydroxyl group of the deoxyribose sugar is acetylated, and the N2 position of the guanine base is protected with an isobutyryl group. Additionally, the 4'-oxygen atom of the sugar is replaced by sulfur, forming a 4'-thio sugar derivative. The acetyl and isobutyryl groups act as protecting groups during oligonucleotide synthesis, ensuring selective reactions at other sites. This compound is primarily used in nucleic acid chemistry for synthesizing modified oligonucleotides, offering enhanced stability, nuclease resistance, and unique structural or biochemical properties for research or therapeutic applications. Synonyms: N-(2-Methyl-1-oxopropyl)-3'-O-acetyl-2'-deoxy-4'-thioguanosine; N2-Isobutyryl-3'-O-acetyl-4'-thio-2'-deoxyguanosine. Molecular formula: C16H21N5O5S. Mole weight: 395.43.
3'-O-Allyl-2'-deoxycytidine
3'-O-Allyl-2'-deoxycytidine is a modified nucleoside where an allyl group is attached to the 3' position of the 2'-deoxyribose sugar in a cytidine molecule. The modification of the 3' hydroxyl group with an allyl group alters the compound's chemical reactivity and may affect its interaction with enzymes or other molecular targets. Such modifications can enhance the stability of the nucleoside in DNA sequences, potentially improving its pharmacokinetic properties for applications in nucleic acid-based therapies, such as gene therapy, or for use in oligonucleotide synthesis. The allyl group could also serve as a handle for further chemical modifications or conjugation to other biomolecules. Synonyms: 2'-Deoxy-3'-O-2-propen-1-ylcytidine; 3'-O-Allyl dC; 3-O-Allyl-2-Deoxycytidine; 1-((2R,4S,5R)-4-(Allyloxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one. Grade: ≥98%. CAS No. 925915-24-8. Molecular formula: C12H17N3O4. Mole weight: 267.28.
4'-Thio-2'-deoxyguanosine
4'-Thio-2'-deoxyguanosine is a modified nucleoside where a sulfur atom replaces the oxygen atom at the 4' position of the deoxyribose sugar in 2'-deoxyguanosine. This sulfur substitution alters the properties of the nucleoside, potentially increasing its stability or changing its interactions in nucleic acid structures. It can be incorporated into oligonucleotides during DNA synthesis for applications in studying DNA structure, function, and stability, or for creating DNA probes and analogs with altered chemical properties. This modification can also be used to investigate the effects of sulfur substitutions on base pairing and DNA hybridization. Synonyms: 2'-Deoxy-4'-thioguanosine; 2-Amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-1H-purin-6-one. Grade: ≥95%. CAS No. 135656-33-6. Molecular formula: C10H13N5O3S. Mole weight: 283.31.
4'-Thiothymidine
4'-Thiothymidine is a modified version of thymidine, where the 4' oxygen of the deoxyribose sugar is replaced by a sulfur atom. This modification introduces unique chemical properties, such as increased stability or altered reactivity, which can be useful in the synthesis of specialized nucleic acid analogs or for studying nucleic acid interactions. Thionucleosides like 4'-thiothymidine may also be used in antiviral or anticancer research due to their potential for incorporating into DNA while disrupting normal cellular processes. Synonyms: 4'-Thio-2'-deoxy-5-methyluridine; 4'-Thio thymidine; 2'-Deoxy-4'-thiothymidine; 1-(2-Deoxy-4-thiopentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-5-methyl-pyrimidine-2,4-dione; 4'-Thio-2'-deoxythymidine. Grade: ≥95%. CAS No. 134111-33-4. Molecular formula: C10H14N2O4S. Mole weight: 258.30.
6-(b-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one, a versatile drug boasting both antiviral and antitumor properties, has become an invaluable instrument in the medicinal world. Through its DNA synthesis interference, it displays its prowess in staving off viruses and cancerous cells alike, thereby serving as a beacon of hope for those stricken with HIV, leukemia, and solid tumors. Notable for its unique structure and mode of operation, this remarkable molecule has cemented its reputation as a priceless commodity in the realm of biomedical research. Synonyms: 6-(2-Deoxy-β-D-erythro-pentofuranosyl)-4,6-dihydro-1H-pyrimido[4,5-c][1,2]oxazin-7(3H)-one; 6-(β-D-2'-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one; dP; P-2'-Deoxyribose; P-Nucleoside (dP); 6-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,6-dihydro-3H-pyrimido[4,5-c][1,2]oxazin-7(8H)-one; Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one. Grade: ≥95%. CAS No. 126128-42-5. Molecular formula: C11H15N3O5. Mole weight: 269.25.
Abasic II phosphoramidite
Abasic II Phosphoramidite, a highly valuable chemical compound, plays a pivotal role in oligonucleotide synthesis, particularly in the context of medicinal applications, as it affords the unique ability to generate modified nucleic acids that combat cancer and genetic disorders. This innovative compound is exceedingly crucial in the biomedical sphere as it transforms the course of advanced therapeutics. Synonyms: 5-O-Dimethoxytrityl-1-O-tert-butyldimethylsilyl-2-deoxyribose-3-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; α-D-erythro-Pentofuranose, 5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-1-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 1835233-43-6. Molecular formula: C41H59N2O7PSi. Mole weight: 750.98.
Bacitracin Zinc
Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zinc bacitracin. CAS No. 1405-89-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0278.
double-stranded uracil-DNA glycosylase
No activity on DNA containing a T/G mispair or single-stranded DNA containing either a site-specific uracil or 3,N4-ethenocytosine residue, significant role for double-stranded uracil-DNA glycosylase in mutation avoidance in non-dividing E. coli. Uracil-DNA glycosylases are widespread enzymes that are found in all living organisms. Uracil-DNA glycosylase (EC 3.2.2.27) and EC 3.2.2.28 form a central part of the DNA-repair machinery since they initiate the DNA base-excision repair pathway by hydrolysing the N-glycosidic bond between uracil and the deoxyribose sugar thereby catalysing the removal of mis-incorporated uracil from DNA. Group: Enzymes. Synonyms: Mug; double-strand uracil-DNA glycosylase; Dug; dsUDG; double-stranded DNA specific UDG; dsDNA specific UDG; UdgB (ambiguous); G:T/U mismatch-specific DNA glycosylase; UDG (ambiguous). Enzyme Commission Number: EC 3.2.2.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3982; double-stranded uracil-DNA glycosylase; EC 3.2.2.28; Mug; double-strand uracil-DNA glycosylase; Dug; dsUDG; double-stranded DNA specific UDG; dsDNA specific UDG; UdgB (ambiguous); G:T/U mismatch-specific DNA glycosylase; UDG (ambiguous). Cat No: EXWM-3982.
Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is an indispensible compound, catering to the synthesis of modified oligonucleotides. Its application in drug R&D facilitates the investigation of nucleic acid interactions and chemical alterations. Synonyms: 1-Ethynyl-dSpacer CE Phosphoramidite; 5'-O-Dimethoxytrityl-1'-ethynyl-2'-deoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; D-ribo-Hept-1-ynitol, 3,6-anhydro-7-O-[bis(4-methoxyphenyl)phenylmethyl]-1,2,4-trideoxy-, 5-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. CAS No. 1173797-55-1. Molecular formula: C37H45N2O6P. Mole weight: 644.74.
N-Acetyl calicheamicin
N-Acetyl calicheamicin is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic. Calicheamicins target DNA and cause strand scission. Calicheamicins bind with DNA in the minor groove, wherein they then undergo a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1,4-didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA, which ultimately leads to strand scission. The specificity of binding of calicheamicin to the minor groove of DNA was demonstrated by Crothers et al. (1999) to be due to the aryltetrasaccharide group of the molecule. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-Acetyl calicheamicin; N-Acetyl-γ-calicheamicin; N-Acetylcalicheamicin γ. Product Category: Others. Appearance: Solid powder. CAS No. 108212-76-6. Molecular formula: C57H76IN3O22S4. Mole weight: 1410.38. Purity: >98%. IUPACName: S-((2R,3S,4S,6S)-6-((((2R,3S,4S,5R,6R)-5-(((2S,4S,5S)-5-(N-ethylacetamido)-4-methoxytetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-6-(((2S,5Z,9R,13Z)-9-hydroxy-12-((methoxycarbonyl)amino)-13-(2-(methyltrisulfanyl)ethylidene)-11-oxobicyclo[7.3.1]trideca-1(12),5-dien-3,7-diyn-2-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl)amino)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl) 4-(((2S,3R,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3-iodo-
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