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Desipramine-2,4,6,8-d4 Hydrochloride (10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine-d4, G-35020-d4, JB-8181-d4, NSc-114901-d4, Norpramin-d4, Nortimil-d4, Pertofran-d4, Pertofrane-d4, Petylyl-d4) Desipramine is an active metabolite of imipramine and has been found to be useful in the treatment of neuropathic pain. It may also be used to treat symptoms of cocaine withdrawal. Desipramine is a tricyclic antidepressant (TCA). Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotonin­norepinephri ne reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer side­effects. Group: Biochemicals. Alternative Names: 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine-d4; G-35020-d4; JB-8181-d4; NSc-114901-d4; Norpramin-d4; Nortimil-d4; Pertofran-d4; Pertofrane-d4; Petylyl-d4. Grades: Highly Purified. CAS No. 61361-34-0. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Desipramine-d3 Labeled tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter. Group: Biochemicals. Alternative Names: 10,11-Dihydro-N-(methyl-d3)-5H-dibenz[b,f]azepine-5-propanamine; G-35020-d3; JB-8181-d3; NSC-114901-d3; Norpramin-d3; Nortimil-d3; Pertofran-d3; Pertofrane-d3; Petylyl-d3. Grades: Highly Purified. CAS No. 65100-49-4. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
Desipramine-d4 Desipramine-d 4 is the deuterium labeled Desipramine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 61361-34-0. Pack Sizes: 500 μg; 1 mg. Product ID: HY-B1272AS. MedChemExpress MCE
Desipramine Ethyl Carbamate Desipramine Ethyl Carbamate is derived from 3-Dimethylaminopropyl Chloride Hydrochloride (D461800), which is is used mainly as a pharmaceutical intermediate for the synthesis of many types of drugs, as an agricultural chemical intermediate, as a photographic chemical intermediate, and as a biochemical reagent for enzyme and other studies. The compound shows mutagenic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 27097-69-4. Pack Sizes: 50mg, 100mg. Molecular Formula: C21H26N2O2, Molecular Weight: 338.44. US Biological Life Sciences. USBiological 3
Worldwide
Desipramine HCl Desipramine HCl can be used in lozenges to cure sore throats however while this is effective in vitro, it is not effective in cases of streptococci infections. Uses: Antidepressive agents, tricyclic. Synonyms: 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine. Grades: > 95%. CAS No. 58-28-6. Molecular formula: C18H23ClN2. Mole weight: 302.84. BOC Sciences 8
Desipramine hydrochloride Desipramine hydrochloride. Group: Biochemicals. Alternative Names: 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine; G-35020; JB-8181. Grades: Highly Purified. CAS No. 58-28-6. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C18H23ClN2, Molecular Weight: 302.84. US Biological Life Sciences. USBiological 7
Worldwide
Desipramine hydrochloride Desipramine hydrochloride is an inhibitor of norepinephrine transporter ( NET ), 5-HT transporter ( SERT ) and dopamine transporter ( DAT ) with K i s of 4, 61 and 78,720 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 58-28-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1272. MedChemExpress MCE
Desipramine impurity 1 Desipramine impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H14N2O2. Mole Weight: 266.3. Catalog: APB11483. Alfa Chemistry Analytical Products 4
Desipramine impurity 10 Desipramine impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H8ClN3O2. Mole Weight: 285.69. Catalog: APB11489. Alfa Chemistry Analytical Products 4
Desipramine impurity 11 Desipramine impurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H20ClN3O. Mole Weight: 329.83. Catalog: APB11491. Alfa Chemistry Analytical Products 4
Desipramine impurity 12 Desipramine impurity 12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H10N4O5. Mole Weight: 314.26. Catalog: APB11493. Alfa Chemistry Analytical Products 4
Desipramine impurity 13 Desipramine impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H11N3O3. Mole Weight: 296.26. Catalog: APB11494. Alfa Chemistry Analytical Products 4
Desipramine impurity 14 Desipramine impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H14N4O. Mole Weight: 254.29. Catalog: APB11495. Alfa Chemistry Analytical Products 4
Desipramine impurity 15 Desipramine impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H29ClN4O. Mole Weight: 400.95. Catalog: APB11496. Alfa Chemistry Analytical Products 4
Desipramine impurity 2 Desipramine impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H13N3O. Mole Weight: 239.28. Catalog: APB11484. Alfa Chemistry Analytical Products 4
Desipramine impurity 3 Desipramine impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 57164-17-7. Molecular Formula: C18H21N3O. Mole Weight: 295.39. Catalog: APB57164177. Alfa Chemistry Analytical Products 2
Desipramine impurity 4 Desipramine impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H19Cl2N3O. Mole Weight: 364.27. Catalog: APB11485. Alfa Chemistry Analytical Products 4
Desipramine impurity 5 Desipramine impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H29ClN4O. Mole Weight: 400.95. Catalog: APB11486. Alfa Chemistry Analytical Products 4
Desipramine impurity 6 Desipramine impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H18ClN3O. Mole Weight: 327.81. Catalog: APB11487. Alfa Chemistry Analytical Products 4
Desipramine impurity 7 Desipramine impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H15N3O2. Mole Weight: 281.32. Catalog: APB11488. Alfa Chemistry Analytical Products 4
Desipramine impurity 8 Desipramine impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H18N4O3. Mole Weight: 338.37. Catalog: APB11490. Alfa Chemistry Analytical Products 4
Desipramine impurity 9 Desipramine impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H16N2O3. Mole Weight: 308.34. Catalog: APB11492. Alfa Chemistry Analytical Products 4
Desipramine (Norpramin®, Pertofrane®) (HRP) Desipramine is an active metabolite of imipramine and has been found to be useful in the treatment of neuropathic pain. It may also be used to treat symptoms of cocaine withdrawal. Desipramine is a tricyclic antidepressant (TCA). Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotonin­norepinephri ne reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer side­effects. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences. USBiological 1
Worldwide
10-Hydroxydesipramine 10-Hydroxydesipramine is a derivative of Desipramine, which is a relatively selective norepinephrine reuptake inhibitor used as a tricyclic antidepressant (TCA). Synonyms: 10-Hydroxydesmethylimipramine; 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepin-10-ol; 5-[3-(Methylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepin-10-ol; 5H-Dibenz(b,f)azepin-10-ol, 10,11-dihydro-5-(3-(methylamino)propyl)-. Grades: ≥95%. CAS No. 4014-82-8. Molecular formula: C18H22N2O. Mole weight: 282.38. BOC Sciences 8
2-Hydroxy Desipramine A metabolite of Desipramine. Group: Biochemicals. Alternative Names: 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepin-2-ol; 2-Hydroxyde methyl imipramine; 2-Hydroxydes methyl imipramine; GP 36329. Grades: Highly Purified. CAS No. 1977-15-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
2-Hydroxydesipramine b-D-glucuronide sodium salt 2-Hydroxydesipramine b-D-glucuronide sodium salt, a highly significant compound in the biomedical industry, holds immense value for research endeavors. Its utilization encompasses the comprehensive exploration of desipramine metabolites to discern their pharmacological activities. Demonstrating remarkable promise, this derivative in sodium salt form finds wide application in the investigation of depression treatment approaches, facilitating the analysis of desipramine's metabolism and therapeutic effects. Molecular formula: C24H30N2O7·Na. Mole weight: 481.49. BOC Sciences 12
2-Hydroxy Desipramine-d3 A labeled metabolite of Desipramine. Group: Biochemicals. Alternative Names: 10,11-Dihydro-5-[3-(methyl-d3-amino)propyl]-5H-dibenz[b,f]azepin-2-ol; 2-Hydroxyde methyl imipramine-d3; 2-Hydroxydes methyl imipramine-d3; GP 36329-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
2-Hydroxy Desipramine-d6 Hydrochloride 2-Hydroxy Desipramine-d6 Hydrochloride is a labeled salt analogue of 2-Hydroxy Desipramine (H936500), a metabolite of Desipramine Hydrochloride (D290050), a tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C18H17D6ClN2O, Molecular Weight: 324.88. US Biological Life Sciences. USBiological 10
Worldwide
2-Hydroxydesipramine Dihydrochloride 2-Hydroxydesipramine Dihydrochloride is a metabolite of Desipramine, a tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter. Synonyms: 5H-Dibenz(b,f)azepin-2-ol, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride (1:2); 5-[3-(Methylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepin-2-ol hydrochloride (1:2); 2-Hydroxydesmethylimipramine dihydrochloride; 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepin-2-ol dihydrochloride. Molecular formula: C18H24Cl2N2O. Mole weight: 355.30. BOC Sciences 8
2-Hydroxydesipramine Dihydrochloride 2-Hydroxydesipramine Dihydrochloride is a metabolite of Desipramine (D290050), a tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C18H22N2O 2HCl. US Biological Life Sciences. USBiological 10
Worldwide
2-Hydroxy desipramine glucuronide A metabolite of Desipramine. Synonyms: 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepin-2-yl β-D-Glucopyranosiduronic Acid; 2-Hydroxydemethylimipramine Glucuronide; 2-Hydroxydesmethylimipramine Glucuronide. Grades: > 95%. CAS No. 25521-31-7. Molecular formula: C24H30N2O7. Mole weight: 458.50. BOC Sciences 12
2-Hydroxydesipramine glucuronide HCl 2-Hydroxydesipramine glucuronide HCl, an indispensable compound in the biomedical sector, holds paramount significance. Its utilization spans the treatment of depression and associated ailments. Remarkably, it serves as a metabolite of desipramine, a pharmacological agent chiefly employed for its antidepressant qualities. Molecular formula: C24H30N2O7·HCl. Mole weight: 494.96 (free acid). BOC Sciences 12
N-(3-Dimethylaminopropyl)desipramine DiHCl Impurity of Desipramine HCl. Synonyms: N-[3-(10,11-Dihydro-5H-dibenzo-[b,f]azepin-5-yl)propyl]-N,N',N'-trimethylpropane-1,3-diamine Dihydrochloride. Grades: > 95%. CAS No. 1838-02-4. Molecular formula: C23H33N3·2HCl. Mole weight: 424.45. BOC Sciences 8
3-Chloroiminodibenzyl 3-Chloroiminodibenzyl is a metabolite of Desipramine and Clomipramine. Group: Biochemicals. Alternative Names: 3-Chloro-10,11-dihydro-5H-dibenz[b,f]azepine. Grades: Highly Purified. CAS No. 32943-25-2. Pack Sizes: 5g. US Biological Life Sciences. USBiological 2
Worldwide
(3-Methylaminopropyl)-5H-dibenz[b,f]azepine (3-Methylaminopropyl)-5H-dibenz[b,f]azepine is an impurity of Desipramine, which is a relatively selective norepinephrine reuptake inhibitor used as a tricyclic antidepressant (TCA). Synonyms: N-Methyl-5H-dibenz[b,f]azepine-5-propanamine; 5-[3-(Methylamino)propyl]-5H-Dibenz[b,f]azepine; G 35967; 5H-Dibenz[b,f]azepine-5-propanamine, N-methyl-; Dehydrodesipramine. CAS No. 2010-13-1. Molecular formula: C18H20N2. Mole weight: 264.36. BOC Sciences 8
Clomipramine HCl EP Impurity F 3-Chloroiminodibenzyl is a metabolite of Desipramine and Clomipramine. Synonyms: 3-Chloroiminodibenzyl; 3-Chloro-10,11-dihydro-5H-dibenz[b,f]azepine. Grades: > 95%. CAS No. 32943-25-2. Molecular formula: C14H12ClN. Mole weight: 229.7. BOC Sciences 7
Proadifen hydrochloride Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC 50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A ( MAO-A ) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine ( DMT ) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-525A; U-5446; RP-5171. CAS No. 62-68-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1311. MedChemExpress MCE
Saredutant Saredutant, aslo known as SR-48968, is a NK2 receptor antagonist for the treatment of major depressive disorder. Saredutant has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Synonyms: (S)-N-methyl-N(4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl)benzamide. Grades: > 95%. CAS No. 142001-63-6. Molecular formula: C31H35Cl2N3O2. Mole weight: 552.55. BOC Sciences 7

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