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| Product | Description | |
|---|---|---|
| 23-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-trimethylsilyl-iso-FK-506 | 23-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-trimethylsilyl-iso-FK-506 is an analog of Tacrolimus, an immunosuppressant that inhibits the activity of FK-506-binding protein. Synonyms: 23-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-trimethylsilyl-iso-Tacrolimus; [3S-[3R*[1R*,2R*,4(1S*,3S*,4S*)],5R*,6S*,10R*,12R*,13R*,14R*,16S*,17S*,24aR*]]-3-[4-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1,3-dimethyl-2-[(trimethylsilyl)oxy]-3-butenyl]-4,5,6,9,10,11,12,13,14,15,16,17,22,23,24,24a-hexadecahydro-5,17-dihydroxy-12,14-dimethoxy-8,10,16-trimethyl-6-(2-propenyl)-13,17-epoxy-3H-pyrido[2,1-c][1,4]oxaazacycloheneicosine-1,18,19(21H)-trione; 13,17-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacycloheneicosine-1,18,19(21H)-trione, 3-[4-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1,3-dimethyl-2-[(trimethylsilyl)oxy]-3-butenyl]-4,5,6,9,10,11,12,13,14,15,16,17,22,23,24,24a-hexadecahydro-5,17-dihydroxy-12,14-dimethoxy-8,10,16-trimethyl-6-(2-propenyl)-, [3S-[3R*[1R*,2R*,4(1S*,3S*,4S*)],5R*,6S*,10R*,12R*,13R*,14R*,16S*,17S*,24aR*]]-. Grade: ≥90%. CAS No. 134556-85-7. Molecular formula: C53H93NO12Si2. Mole weight: 992.48. |  |
| 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers) | 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers) is an intermediate of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy Tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-(2,3-dihydroxypropyl)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[(E)-2-[(1R,3R,4R)-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4S,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-; Tacrolimus Impurity 17. Grade: ≥90%. CAS No. 1356932-17-6. Molecular formula: C56H99NO14Si2. Mole weight: 1066.55. | |
| 25,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers) | An intermediate in the preparation of labeled FK-506 (Tacrolimus). Group: Biochemicals. Alternative Names: 25,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy Tacrolimus. Grades: Highly Purified. CAS No. 1356932-17-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| 33-tert-Butyldimethylsilyloxy-FK 506 | 33-tert-Butyldimethylsilyloxy-FK 506 is an intermediate of iso-Tacrolimus. Synonyms: [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-3-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone; 33-tert-Butyldimethylsilyloxy-Tacrolimus; Tacrolimus Impurity 26; Tacrolimus Impurity 15. Grade: ≥95%. CAS No. 104987-25-9. Molecular formula: C50H83NO12Si. Mole weight: 918.28. | |
| 5-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506 | 5-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506 is an analog of Tacrolimus, an immunosuppressant that inhibits the activity of FK-506-binding protein. Uses: Analog of iso-fk-506. Synonyms: 13,17-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacycloheneicosine-1,18,19(21H)-trione, 3-[4-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-2-hydroxy-1,3-dimethyl-3-butenyl]-4,5,6,9,10,11,12,13,14,15,16,17,22,23,24,24a-hexadecahydro-5,17-dihydroxy-12,14-dimethoxy-8,10,16-trimethyl-6-(2-propenyl)-, [3S-[3R*[1R*,2R*,3E,4(1S*,3S*,4S*)],5R*,6S*,7E,10R*,12R*,13R*,14R*,16S*,17S*,24aR*]]-; [3S-[3R*[1R*,2R*,3E,4(1S*,3S*,4S*)],5R*,6S*,7E,10R*,12R*,13R*,14R*,16S*,17S*,24aR*]]-3-[4-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-2-hydroxy-1,3-dimethyl-3-butenyl]-4,5,6,9,10,11,12,13,14,15,16,17,22,23,24,24a-hexadecahydro-5,17-dihydroxy-12,14-dimethoxy-8,10,16-trimethyl-6-(2-propenyl)-13,17-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacycloheneicosine-1,18,19(21H)-trione. Grade: 95%. CAS No. 134556-79-9. Molecular formula: C50H85NO12Si. Mole weight: 920.29. | |
| 8-Epitacrolimus | 8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus. Group: Biochemicals. Alternative Names: (-)-8-epi-Tacrolimus; [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8R*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: Highly Purified. CAS No. 129212-35-7. Pack Sizes: 500ug. Molecular Formula: C??H??NO??, Molecular Weight: 804.02. US Biological Life Sciences. | Worldwide |
| Dihydro FK-506 | A novel analog of FK-506 macrocycle. Group: Biochemicals. Alternative Names: Tsukubamycin B; Dihydro Tacrolimus; [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8S*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-15, 19-Epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-15, 19-Epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: Highly Purified. CAS No. 104987-30-6. Pack Sizes: 1mg, 2.5mg, 5mg. Molecular Formula: C??H??NO??, Molecular Weight: 806.03. US Biological Life Sciences. | Worldwide |
| FK-506 3'-Methyl Ether | It is a fermentation process impurity of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Uses: It is a fermentation process impurity. it is formed during tacrolimus ((f370000) fermentation using strain of streptomyces tsukubaensis. Synonyms: 3-[2-(3,4-Dimethoxycyclohexyl)-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone. Grade: 95%. CAS No. 124554-16-1. Molecular formula: C45H71NO12. Mole weight: 818.04. | |
| Tacrolimus | Tacrolimus. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone. CAS No. 104987-11-3. Molecular formula: C44H69NO12. Mole weight: 804.02. Catalog: APB104987113. |  |
| Tacrolimus EP Impurity A | Ascomycin, isolated from Streptomyces, suppresses immune response in vitro with IC50 of 0.55 nM for mouse mixed lymphocyte. Uses: Anti-bacterial agents. Synonyms: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-ethyl-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; FK-520; FR900520; FR-900520; FR 900520; L 683590; L-683590; L683590; Changchuanmycin; Immunomycin; Ascomycin; Tacrolimus Related Compound A USP; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-. Grade: ≥90% by HPLC. CAS No. 104987-12-4. Molecular formula: C43H69NO12. Mole weight: 792.00. | |
| Tacrolimus EP Impurity A | Tacrolimus EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone. CAS No. 104987-12-4. Molecular formula: C43H69NO12. Mole weight: 792.01. Catalog: APB104987124. | |
| Tacrolimus EP Impurity C | Tacrolimus EP Impurity C is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,12,18-trimethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; 10-Desmethyl tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,12,18-trimethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-; Tacrolimus monohydrate EP impurity C; (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl]-14,16-dimethoxy-4,12,18-trimethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21-(4H,23H)-tetrone; Desmethyl tacrolimus. Grade: ≥95%. Molecular formula: C43H67NO12. Mole weight: 789.99. | |
| Tacrolimus EP Impurity D | Tacrolimus EP Impurity D is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S,4R,5S,8S,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; 8-epi Tacrolimus; 8-Epitacrolimus; Tacrolimus anhydrous 8-epimer; Tacrol. Grade: ≥90% by HPLC. CAS No. 129212-35-7. Molecular formula: C44H69NO12. Mole weight: 804.04. | |
| Tacrolimus EP Impurity E | Tacrolimus EP Impurity E is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-propyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; Dihydro Tacrolimus; Dihydro-FK 506; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotr. Grade: ≥90% by HPLC. CAS No. 104987-30-6. Molecular formula: C44H71NO12. Mole weight: 806.06. | |
| Tacrolimus EP Impurity E | Tacrolimus EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-propyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone. CAS No. 104987-30-6. Molecular formula: C44H71NO12. Mole weight: 806.03. Catalog: APB104987306. | |
| Tacrolimus EP Impurity F | Tacrolimus EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,E)-8-allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,24,25,26,26a-hexadecahydro-1H-pyrido[2,1-c][1,4]oxaaz. CAS No. 1393890-33-9. Molecular formula: C44H69NO12. Mole weight: 804.02. Catalog: APB1393890339. | |
| Tacrolimus EP Impurity G | Tacrolimus EP Impurity G is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; Tacrolimus compound II; Tacrolimus anhydrous 19-epimer; 19-Epi FK-506; 1. Grade: ≥90% by HPLC. CAS No. 144490-63-1. Molecular formula: C44H69NO12. Mole weight: 804.04. | |
| Tacrolimus monohydrate | Tacrolimus monohydrate is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Synonyms: Tacrolimus Hydrate; Tsukubaenolide hydrate; (3S,?4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine?-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-hydrate. Grade: >98%. CAS No. 109581-93-3. Molecular formula: C44H71NO13. Mole weight: 822.03. | |
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