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| Product | Description | |
|---|---|---|
| Dihydro Tacrolimus | Cas No. 104987-30-6. |  |
| 23-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-trimethylsilyl-iso-FK-506 | 23-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-trimethylsilyl-iso-FK-506 is an analog of Tacrolimus, an immunosuppressant that inhibits the activity of FK-506-binding protein. Synonyms: 23-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-trimethylsilyl-iso-Tacrolimus; [3S-[3R*[1R*, 2R*, 4(1S*, 3S*, 4S*)], 5R*, 6S*, 10R*, 12R*, 13R*, 14R*, 16S*, 17S*, 24aR*]]-3-[4-[4-[[(1, 1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1, 3-dimethyl-2-[(trimethylsilyl)oxy]-3-butenyl]-4, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 24, 24a-hexadecahydro-5, 17-dihydroxy-12, 14-dimethoxy-8, 10, 16-trimethyl-6-(2-propenyl)-13, 17-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacycloheneicosine-1, 18, 19(21H)-trione; 13,17-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacycloheneicosine-1,18,19(21H)-trione, 3-[4-[4-[[(1, 1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1, 3-dimethyl-2-[(trimethylsilyl)oxy]-3-butenyl]-4, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 24, 24a-hexadecahydro-5, 17-dihydroxy-12, 14-dimethoxy-8, 10, 16-trimethyl-6-(2-propenyl)-, [3S-[3R*[1R*, 2R*, 4(1S*, 3S*, 4S*)], 5R*, 6S*, 10R*, 12R*, 13R*, 14R*, 16S*, 17S*, 24aR*]]-. Grades: ≥90%. CAS No. 134556-85-7. Molecular formula: C53H93NO12Si2. Mole weight: 992.48. | |
| 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers) | 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers) is an intermediate of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy Tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-(2, 3-dihydroxypropyl)-5-[[(1, 1-dimethylethyl)dimethylsilyl]oxy]-3-[(E)-2-[(1R, 3R, 4R)-4-[[(1, 1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-19-hydroxy-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-, (3S, 4S, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; Tacrolimus Impurity 17. Grades: ≥90%. CAS No. 1356932-17-6. Molecular formula: C56H99NO14Si2. Mole weight: 1066.55. | |
| 25,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers) | An intermediate in the preparation of labeled FK-506 (Tacrolimus). Group: Biochemicals. Alternative Names: 25,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy Tacrolimus. Grades: Highly Purified. CAS No. 1356932-17-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| 33-tert-Butyldimethylsilyloxy-FK 506 | 33-tert-Butyldimethylsilyloxy-FK 506 is an intermediate of iso-Tacrolimus. Synonyms: [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8S*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-3-[2-[4-[[(1, 1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone; 33-tert-Butyldimethylsilyloxy-Tacrolimus; Tacrolimus Impurity 26; Tacrolimus Impurity 15. Grades: ≥95%. CAS No. 104987-25-9. Molecular formula: C50H83NO12Si. Mole weight: 918.28. | |
| 8-Epitacrolimus | 8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus. Group: Biochemicals. Alternative Names: (-)-8-epi-Tacrolimus; [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8R*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: Highly Purified. CAS No. 129212-35-7. Pack Sizes: 500ug. Molecular Formula: C??H??NO??, Molecular Weight: 804.02. US Biological Life Sciences. | Worldwide |
| Dihydro FK-506 | A novel analog of FK-506 macrocycle. Group: Biochemicals. Alternative Names: Tsukubamycin B; Dihydro Tacrolimus; [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8S*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-15, 19-Epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-15, 19-Epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: Highly Purified. CAS No. 104987-30-6. Pack Sizes: 1mg, 2.5mg, 5mg. Molecular Formula: C??H??NO??, Molecular Weight: 806.03. US Biological Life Sciences. | Worldwide |
| FK-506 3'-Methyl Ether | It is a fermentation process impurity of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Uses: It is a fermentation process impurity. it is formed during tacrolimus ((f370000) fermentation using strain of streptomyces tsukubaensis. Synonyms: 3-[2-(3, 4-Dimethoxycyclohexyl)-1-methylethenyl]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propen-1-yl)-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: 95%. CAS No. 124554-16-1. Molecular formula: C45H71NO12. Mole weight: 818.04. | |
| Tacrolimus | Tacrolimus. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone. CAS No. 104987-11-3. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB104987113. |  |
| Tacrolimus 31 DMT | Tacrolimus 31 DMT is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: O-desmethyl Tacrolimus; Hydroxy Tacrolimus; (18E)-17-Allyl-12-[(1E)-1-(3,4-dihydroxycyclohexyl)-1-propen-2-yl]-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone. Grades: >98%. CAS No. 135635-47-1. Molecular formula: C43H67NO12. Mole weight: 789.99. | |
| Tacrolimus 31-DMT | Tacrolimus 31-DMT is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: 12-[1-(3,4-Dihydroxycyclohexyl)prop-1-en-2-yl]-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone; Tacrolimus 31 DMT; VHOPGJHKSPGXIZ-UHFFFAOYSA-N; 17-Allyl-1,14-dihydroxy-12-[2-(3,4-dihydroxycyclohexyl)-1-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene-2,3,10,16-tetraone. CAS No. 127984-76-3. Molecular formula: C43H67NO12. Mole weight: 789.99. | |
| Tacrolimus EP Impurity A | Ascomycin, isolated from Streptomyces, suppresses immune response in vitro with IC50 of 0.55 nM for mouse mixed lymphocyte. Uses: Anti-bacterial agents. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-ethyl-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; FK-520; FR900520; FR-900520; FR 900520; L 683590; L-683590; L683590; Changchuanmycin; Immunomycin; Ascomycin; Tacrolimus Related Compound A USP; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-, [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8S*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-. Grades: ≥90% by HPLC. CAS No. 104987-12-4. Molecular formula: C43H69NO12. Mole weight: 792.00. | |
| Tacrolimus EP Impurity A | Tacrolimus EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Ethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. CAS No. 104987-12-4. Molecular Formula: C43H69NO12. Mole Weight: 792.01. Catalog: APB104987124. | |
| Tacrolimus EP Impurity C | Tacrolimus EP Impurity C is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 12, 18-trimethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; 10-Desmethyl tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 12, 18-trimethyl-8-(2-propen-1-yl)-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; Tacrolimus monohydrate EP impurity C; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Allyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl]-14, 16-dimethoxy-4, 12, 18-trimethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone; Desmethyl tacrolimus. Grades: ≥95%. Molecular formula: C43H67NO12. Mole weight: 789.99. | |
| Tacrolimus EP Impurity D | Tacrolimus EP Impurity D is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; 8-epi Tacrolimus; 8-Epitacrolimus; Tacrolimus anhydrous 8-epimer; Tacrolimus 8-epimer [USP-RS]; Tacrolimus monohydrate impurity D [EP]; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8R*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-; (-)-8-epi-Tacrolimus; (3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Allyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-{(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: ≥90% by HPLC. CAS No. 129212-35-7. Molecular formula: C44H69NO12. Mole weight: 804.04. | |
| Tacrolimus EP Impurity D | Tacrolimus EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 8-epi Tacrolimus; (3S, 4R, 5S, 8S, 12S, 14S, 15R, 16S, 18R, 19R, 26aS, E)-8-allyl-5, 19-dihydroxy-3-((E)-1-((1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-3H-15, 19-epoxypyrido[2, 1-c][1]oxa[4]azacyclotricosine-1, 7, 20, 21(4H, 23H)-tetraone. CAS No. 129212-35-7. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB129212357. | |
| Tacrolimus EP Impurity E | Tacrolimus EP Impurity E is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; Dihydro Tacrolimus; Dihydro-FK 506; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-. Grades: ≥90% by HPLC. CAS No. 104987-30-6. Molecular formula: C44H71NO12. Mole weight: 806.06. | |
| Tacrolimus EP Impurity E | Tacrolimus EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone. CAS No. 104987-30-6. Molecular Formula: C44H71NO12. Mole Weight: 806.03. Catalog: APB104987306. | |
| Tacrolimus EP Impurity F | Tacrolimus EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 12S, 14S, 15R, 16S, 18R, 26aS, E)-8-allyl-5, 15-dihydroxy-3-((E)-1-((1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-3, 4, 5, 6, 11, 12, 13, 14, 15, 16, 17, 18, 24, 25, 26, 26a-hexadecahydro-1H-pyrido[2, 1-c][1, 4]oxaaz. CAS No. 1393890-33-9. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB1393890339. | |
| Tacrolimus Impurity 2 | One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacroliums Impurity D; [3R-[3R*(1R*, 3R*, 4R*), 4E, 6S*, 7S*, 10R*, 11E, 14S*, 16S*, 17R*, 18S*, 20R*, 21R*, 28aS*]]-7, 8, 10, 13, 14, 15, 16, 17, 18, 19, 20, 21, 26, 27, 28, 28a-Hexadecahydro-7, 21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16, 18-dimethoxy-4, 6, 12, 14, 20-pentamethyl-10-(2-propenyl)-7, 21-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclopentacosine-1, 9, 22, 23(6H, 25H)-tetrone. Grades: > 95%. CAS No. 131944-48-4. Molecular formula: C44H69NO12. Mole weight: 804.04. | |
| Tacrolimus regioisomer | Tacrolimus regioisomer is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (4E, 11E)-10-Allyl-7, 8, 10, 13, 14, 15, 16, 17, 18, 19, 20, 21, 26, 22, 28, 28a-hexadecahydro-7, 21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16, 18-dimethoxy-4, 6, 12, 14, 20-pentamethyl-17, 21-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclopentacosine-1, 9, 22, 23(6H, 25H)-tetrone. Molecular formula: C44H69NO12. Mole weight: 804.03. | |
| Tacrolimus System Suitability Mixture | It is a mixture of tacrolimus, ascomycin and tacrolimus 8-propyl analog. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propen-1-yl)-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone mix. with (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Ethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone mix. with (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-{(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-8-propyl-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone. Molecular formula: C44H69NO12.C43H69NO12.C44H71NO12. Mole weight: 2402.10. | |
| Tacrolimus USP Related Compound A | Tacrolimus USP Related Compound A is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: USP Tacrolimus Related Compound A; (E)-8-Ethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone. Grades: ≥95%. Molecular formula: C43H69NO12. Mole weight: 792.01. | |
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