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| Product | Description | |
|---|---|---|
| Dihydrorhodamine 123 | Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DHR 123. CAS No. 109244-58-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101894. |  |
| Rhodamine, Dihydro 123, Dihydrochloride Salt (Dihydrorhodamine) | Dihydrorhodamine 123 dihydrochloride is the HCl salt form of dihydrorhodamine 123 and is functionally equivalent to the latter. However, dihydrorhodamine 123 dihydrochloride is more water soluble and more stable to air oxidation than dihydrorhodamine 123. Thus, dihydrorhodamine 123 dihydrochloride is easier to use and can be stored longer than dihydrorhodamine 123.Dihydrorhodamine 123 (DHR 123) is a cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite. It is not fluorescent until oxidized by ROS to the highly fluorescent product Rhodamine 123. Neither NO, superoxide, nor hydrogen peroxide alone appear to oxidize DHR, rather, these ROS are thought to combine with other cellular components such as cytochrome c oxidase or Fe2+ in order to oxidize DHR 123 to its fluorescent derivative Rhodamine 123. Formation of Rhodamine 123 can be monitored by fluorescence spectroscopy using excitation and emission wavelengths of 500 and 536nm, respectively, or by absorbance spectroscopy at 500 nm (ε = 78,800 M-1cm-1). Group: Biochemicals. Alternative Names: D 23806; D 632; DHR. Grades: Highly Purified. CAS No. 109244-58-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?O? 2HCl, Molecular Weight: 419. US Biological Life Sciences. |  Worldwide |
| Dihydrofluorescein diacetate | Dihydrofluorescein diacetate is a chemical used for intracellular staining. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular concentrations than the other redox sensors such as 2', 7'-dichlorodi hydrofluorescein and Dihydrorhodamine 123. Dihydrofluorescein diacetate is first hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by hydrogen peroxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 35340-49-9. Pack Sizes: 500mg, 1000mg. Molecular Formula: C24H18O7, Molecular Weight: 418.4. US Biological Life Sciences. | Worldwide |
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