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This enzyme is involved in naphthalene degradation. Requires Fe2+. Group: Enzymes. Synonyms: 1,2-DHN dioxygenase; DHNDO; 1,2-dihydroxynaphthalene oxygenase; 1,2-dihydroxynaphthalene:oxygen oxidoreductase. Enzyme Commission Number: EC 1.13.11.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0575; 1,2-dihydroxynaphthalene dioxygenase; EC 1.13.11.56; 1,2-DHN dioxygenase; DHNDO; 1,2-dihydroxynaphthalene oxygenase; 1,2-dihydroxynaphthalene:oxygen oxidoreductase. Cat No: EXWM-0575.
1-hydroxy-2-naphthoate 1,2-dioxygenase
Requires Fe2+. Involved, with EC 4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase, in the metabolism of phenanthrene in bacteria. Group: Enzymes. Synonyms: 1-hydroxy-2-naphthoate dioxygenase; 1-hydroxy-2-naphthoate-degrading enzyme; 1-hydroxy-2-naphthoic acid dioxygenase; 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.38. CAS No. 85941-64-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0557; 1-hydroxy-2-naphthoate 1,2-dioxygenase; EC 1.13.11.38; 85941-64-6; 1-hydroxy-2-naphthoate dioxygenase; 1-hydroxy-2-naphthoate-degrading enzyme; 1-hydroxy-2-naphthoic acid dioxygenase; 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0557.
2,3-dihydroxybenzoate 2,3-dioxygenase
Also acts, more slowly, with 2,3-dihydroxy-4-methylbenzoate and 2,3-dihydroxy-4-isopropylbenzoate. Group: Enzymes. Synonyms: 2,3-dihydroxybenzoate 2,3-oxygenase; 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.28. CAS No. 56802-97-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0547; 2,3-dihydroxybenzoate 2,3-dioxygenase; EC 1.13.11.28; 56802-97-2; 2,3-dihydroxybenzoate 2,3-oxygenase; 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0547.
2,3-dihydroxybenzoate 3,4-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Other names in common use include o-pyrocatechuate oxygenase, 2,3-dihydroxybenzoate 1,2-dioxygenase, 2,3-dihydroxybenzoic oxygenase, and 2,3-dihydroxybenzoate oxygenase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: o-pyrocatechuate oxygenase; 2,3-dihydroxybenzoate 1,2-dioxygenase; 2,3-dihydroxybenzoic oxygenase; 2,3-dihydroxybenzoate oxygenase; 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.14. CAS No. 9032-31-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0533; 2,3-dihydroxybenzoate 3,4-dioxygenase; EC 1.13.11.14; 9032-31-9; o-pyrocatechuate oxygenase; 2,3-dihydroxybenzoate 1,2-dioxygenase; 2,3-dihydroxybenzoic oxygenase; 2,3-dihydroxybenzoate oxygenase; 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Cat No: EXWM-0533.
2,3-dihydroxyindole 2,3-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). This enzyme participates in tryptophan metabolism. Group: Enzymes. Synonyms: 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.23. CAS No. 37256-62-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0542; 2,3-dihydroxyindole 2,3-dioxygenase; EC 1.13.11.23; 37256-62-5; 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0542.
The enzyme is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants, most commonly from the family of Poaceae (grasses). Group: Enzymes. Synonyms: BX6 (gene name); DIBOA-Glc dioxygenase. Enzyme Commission Number: EC 1.14.20.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1018; 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase; EC 1.14.20.2; BX6 (gene name); DIBOA-Glc dioxygenase. Cat No: EXWM-1018.
2,4'-dihydroxyacetophenone dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving). This enzyme is also called (4-hydroxybenzoyl)methanol oxygenase. This enzyme participates in bisphenol a degradation. Group: Enzymes. Synonyms: (4-hydroxybenzoyl)methanol oxygenase. Enzyme Commission Number: EC 1.13.11.41. CAS No. 257617-97-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0561; 2,4'-dihydroxyacetophenone dioxygenase; EC 1.13.11.41; 257617-97-3; (4-hydroxybenzoyl)methanol oxygenase. Cat No: EXWM-0561.
2,4-dinitrotoluene dioxygenase
This enzyme, characterized from the bacterium Burkholderia sp. strain DNT, is a member of the naphthalene family of bacterial Rieske non-heme iron dioxygenases. It comprises a multicomponent system, containing a Rieske [2Fe-2S] ferredoxin, an NADH-dependent flavoprotein reductase (EC 1.18.1.3, ferredoxin-NAD+ reductase), and an α3β3 oxygenase. The enzyme forms a cis-dihydroxylated product that spontaneously rearranges to form a catechol with accompanying release of nitrite. It does not act on nitrobenzene. cf. EC 1.14.12.23, nitroarene dioxygenase. Group: Enzymes. Synonyms: dntA (gene name). Enzyme Commission Number: EC 1.14.12.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0691; 2,4-dinitrotoluene dioxygenase; EC 1.14.12.24; dntA (gene name). Cat No: EXWM-0691.
2,5-dihydroxypyridine 5,6-dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: 2,5-dihydroxypyridine oxygenase; pyridine-2,5-diol dioxygenase; NicX. Enzyme Commission Number: EC 1.13.11.9. CAS No. 9029-57-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0604; 2,5-dihydroxypyridine 5,6-dioxygenase; EC 1.13.11.9; 9029-57-6; 2,5-dihydroxypyridine oxygenase; pyridine-2,5-diol dioxygenase; NicX. Cat No: EXWM-0604.
Requires Fe2+. The enzyme, characterized from a marine bacterium, is involved in a 2-aminoethylphosphonate degradation pathway. Group: Enzymes. Synonyms: phnZ (gene name). Enzyme Commission Number: EC 1.13.11.78. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0598; 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming); EC 1.13.11.78; phnZ (gene name). Cat No: EXWM-0598.
2-amino-5-chlorophenol 1,6-dioxygenase
The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.13.11.74, 2-aminophenol 1,6-dioxygenase. Group: Enzymes. Synonyms: cnbC (gene name); 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.76. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0596; 2-amino-5-chlorophenol 1,6-dioxygenase; EC 1.13.11.76; cnbC (gene name); 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (decyclizing). Cat No: EXWM-0596.
2-aminobenzenesulfonate 2,3-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of two atoms o oxygen into the other donor. The systematic name of this enzyme class is 2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming). This enzyme is also called 2-aminosulfobenzene 2,3-dioxygenase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 2-aminosulfobenzene 2,3-dioxygenase. Enzyme Commission Number: EC 1.14.12.14. CAS No. 156621-16-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0683; 2-aminobenzenesulfonate 2,3-dioxygenase; EC 1.14.12.14; 156621-16-8; 2-aminosulfobenzene 2,3-dioxygenase. Cat No: EXWM-0683.
2-aminoethylphosphonate dioxygenase
Requires Fe2+ and ascorbate. The enzyme, characterized from an uncultured marine bacterium, is involved in a (2-aminoethyl)phosphonate degradation pathway. Group: Enzymes. Synonyms: phnY (gene name). Enzyme Commission Number: EC 1.14.11.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0665; 2-aminoethylphosphonate dioxygenase; EC 1.14.11.46; phnY (gene name). Cat No: EXWM-0665.
2-aminophenol 1,6-dioxygenase
The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). The enzyme also has some activity with 2-amino-5-methylphenol and 2-amino-4-methylphenol. The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.13.11.76, 2-amino-5-chlorophenol 1,6-dioxygenase. Group: Enzymes. Synonyms: amnA (gene name); amnB (gene name); 2-aminophenol:oxygen 1,6-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.74. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0594; 2-aminophenol 1,6-dioxygenase; EC 1.13.11.74; amnA (gene name); amnB (gene name); 2-aminophenol:oxygen 1,6-oxidoreductase (decyclizing). Cat No: EXWM-0594.
2'-deoxymugineic-acid 2'-dioxygenase
Requires iron(II). It is also likely that this enzyme can catalyse the hydroxylation of 3-epihydroxy-2'-deoxymugineic acid to form 3-epihydroxymugineic acid. Group: Enzymes. Synonyms: IDS3. Enzyme Commission Number: EC 1.14.11.24. CAS No. 133758-62-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0641; 2'-deoxymugineic-acid 2'-dioxygenase; EC 1.14.11.24; 133758-62-0; IDS3. Cat No: EXWM-0641.
2-halobenzoate 1,2-dioxygenase
A multicomponent enzyme system composed of a dioxygenase component and an electron transfer component. The latter contains FAD. The enzyme, characterized from the bacterium Burkholderia cepacia 2CBS, has a broad substrate specificity. Substrates include 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate, which are processed in this order of preference. Group: Enzymes. Synonyms: 2-chlorobenzoate 1,2-dioxygenase. Enzyme Commission Number: EC 1.14.12.13. CAS No. 125268-83-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0682; 2-halobenzoate 1,2-dioxygenase; EC 1.14.12.13; 125268-83-9; 2-chlorobenzoate 1,2-dioxygenase. Cat No: EXWM-0682.
2-hydroxyethylphosphonate dioxygenase
Requires non-heme-Fe(II). Isolated from some bacteria including Streptomyces hygroscopicus and Streptomyces viridochromogenes. The pro-R hydrogen at C-2 of the ethyl group is retained by the formate ion. Any stereochemistry at C-1 of the ethyl group is lost. One atom from dioxygen is present in each product. Involved in phosphinothricin biosynthesis. Group: Enzymes. Synonyms: HEPD; phpD (gene name); 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming). Enzyme Commission Number: EC 1.13.11.72. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0592; 2-hydroxyethylphosphonate dioxygenase; EC 1.13.11.72; HEPD; phpD (gene name); 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming). Cat No: EXWM-0592.
2-hydroxyquinoline 5,6-dioxygenase
3-Methylquinolin-2-ol, quinolin-8-ol and quinolin-2,8-diol are also substrates. Quinolin-2-ols exist largely as their quinolin-2(1H)-one tautomers. Group: Enzymes. Synonyms: 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase; quinolin-2-ol 5,6-dioxygenase; quinolin-2(1H)-one 5,6-dioxygenase. Enzyme Commission Number: EC 1.14.12.16. CAS No. 172399-50-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0685; 2-hydroxyquinoline 5,6-dioxygenase; EC 1.14.12.16; 172399-50-7; 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase; quinolin-2-ol 5,6-dioxygenase; quinolin-2(1H)-one 5,6-dioxygenase. Cat No: EXWM-0685.
2-oxoglutarate dioxygenase (ethylene-forming)
This is one of two simultaneous reactions catalysed by the enzyme, which is responsible for ethylene production in bacteria of the Pseudomonas syringae group. In the other reaction [EC 1.14.11.34, 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)] the enzyme catalyses the mono-oxygenation of both 2-oxoglutarate and L-arginine, forming succinate, carbon dioxide and L-hydroxyarginine, which is subsequently cleaved into guanidine and (S)-1-pyrroline-5-carboxylate.The enzymes catalyse two cycles of the ethylene-forming reaction for each cycle of the succinate-forming reaction, so that the stoichiometry of the products ethylene and succinate is 2:1. Group: Enzymes. Synonyms: ethylene-forming enzyme; EFE. Enzyme Commission Number: EC 1.13.12.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0611; 2-oxoglutarate dioxygenase (ethylene-forming); EC 1.13.12.19; ethylene-forming enzyme; EFE. Cat No: EXWM-0611.
Requires Fe2+. Also acts on 3-isopropylcatechol and 3-tert-butyl-5-methylcatechol. Group: Enzymes. Synonyms: steroid 4,5-dioxygenase; 3-alkylcatechol 2,3-dioxygenase; 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.25. CAS No. 37256-63-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0544; 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase; EC 1.13.11.25; 37256-63-6; steroid 4,5-dioxygenase; 3-alkylcatechol 2,3-dioxygenase; 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing). Cat No: EXWM-0544.
3,4-dihydroxyphenylacetate 2,3-dioxygenase
An iron protein. Group: Enzymes. Synonyms: 3,4-dihydroxyphenylacetic acid 2,3-dioxygenase; HPC dioxygenase; homoprotocatechuate 2,3-dioxygenase; 3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.15. CAS No. 37256-56-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0534; 3,4-dihydroxyphenylacetate 2,3-dioxygenase; EC 1.13.11.15; 37256-56-7; 3,4-dihydroxyphenylacetic acid 2,3-dioxygenase; HPC dioxygenase; homoprotocatechuate 2,3-dioxygenase; 3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0534.
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
The enzyme, characterized from bacteria Streptomyces toyocaensis and Amycolatopsis orientalis, is involved in the biosynthesis of (3,5-dihydroxyphenyl)glycine, a component of the glycopeptide antibiotic vancomycin. Group: Enzymes. Synonyms: DpgC. Enzyme Commission Number: EC 1.13.11.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0601; (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase; EC 1.13.11.80; DpgC. Cat No: EXWM-0601.
3-carboxyethylcatechol 2,3-dioxygenase
An iron protein. This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation. Group: Enzymes. Synonyms: 2,3-dihydroxy-β-phenylpropionic dioxygenase; 2,3-dihydroxy-β-phenylpropionate oxygenase; 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase; 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.16. CAS No. 105503-63-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0535; 3-carboxyethylcatechol 2,3-dioxygenase; EC 1.13.11.16; 105503-63-7; 2,3-dihydroxy-β-phenylpropionic dioxygenase; 2,3-dihydroxy-β-phenylpropionate oxygenase; 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase; 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0535.
3-hydroxy-2-methylpyridinecarboxylate dioxygenase
A flavoprotein (FAD). Group: Enzymes. Synonyms: methylhydroxypyridinecarboxylate oxidase; 2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase; methylhydroxypyridine carboxylate dioxygenase; 3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect]; 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.14.12.4. CAS No. 37256-69-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0693; 3-hydroxy-2-methylpyridinecarboxylate dioxygenase; EC 1.14.12.4; 37256-69-2; methylhydroxypyridinecarboxylate oxidase; 2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase; methylhydroxypyridine carboxylate dioxygenase; 3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect]; 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing). Cat No: EXWM-0693.
3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
Does not contain a metal centre or organic cofactor. Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with concomitant release of carbon monoxide. The enzyme from Arthrobacter sp. can also act on 3-hydroxy-4-oxoquinoline, forming N-formylanthranilate and CO (cf. EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase), but more slowly. Group: Enzymes. Synonyms: (1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase. Enzyme Commission Number: EC 1.13.11.48. CAS No. 160995-63-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0566; 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase; EC 1.13.11.48; 160995-63-1; (1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase. Cat No: EXWM-0566.
3-hydroxy-4-oxoquinoline 2,4-dioxygenase
Does not contain a metal centre or organic cofactor. Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with concomitant release of carbon monoxide. The enzyme from Pseudomonas putida is highly specific for this substrate. Group: Enzymes. Synonyms: (1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase; 3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase; 3-hydroxy-4(1H)-one, 2,4-dioxygenase; quinoline-3,4-diol 2,4-dioxygenase. Enzyme Commission Number: EC 1.13.11.47. CAS No. 238093-32-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0565; 3-hydroxy-4-oxoquinoline 2,4-dioxygenase; EC 1.13.11.47; 238093-32-8; (1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase; 3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase; 3-hydroxy-4(1H)-one, 2,4-dioxygenase; quinoline-3,4-diol 2,4-dioxygenase. Cat No: EXWM-0565.
3-hydroxyanthranilate 3,4-dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid oxygenase; 3-hydroxyanthranilic oxygenase; 3-hydroxyanthranilic acid oxidase; 3HAO; 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.6. CAS No. 9029-50-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0579; 3-hydroxyanthranilate 3,4-dioxygenase; EC 1.13.11.6; 9029-50-9; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid oxygenase; 3-hydroxyanthranilic oxygenase; 3-hydroxyanthranilic acid oxidase; 3HAO; 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing). Cat No: EXWM-0579.
3-phenylpropanoate dioxygenase
This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation. It catalyses the insertion of both atoms of molecular oxygen into positions 2 and 3 of the phenyl ring of 3-phenylpropanoate or (2E)-3-phenylprop-2-enoate. Group: Enzymes. Synonyms: HcaA1A2CD; Hca dioxygenase; 3-phenylpropionate dioxygenase. Enzyme Commission Number: EC 1.14.12.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0688; 3-phenylpropanoate dioxygenase; EC 1.14.12.19; HcaA1A2CD; Hca dioxygenase; 3-phenylpropionate dioxygenase. Cat No: EXWM-0688.
4-chlorophenylacetate 3,4-dioxygenase
A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate. Group: Enzymes. Enzyme Commission Number: EC 1.14.12.9. CAS No. 105006-00-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0697; 4-chlorophenylacetate 3,4-dioxygenase; EC 1.14.12.9; 105006-00-6. Cat No: EXWM-0697.
4-hydroxyphenylpyruvate dioxygenase
The Pseudomonas enzyme contains one Fe3+ per mole of enzyme; the enzymes from other sources may contain essential iron or copper. Group: Enzymes. Synonyms: p-hydroxyphenylpyruvic hydroxylase; p-hydroxyphenylpyruvate hydroxylase; p-hydroxyphenylpyruvate oxidase; p-hydroxyphenylpyruvic oxidase; p-hydroxyphenylpyruvate dioxygenase; p-hydroxyphenylpyruvic acid hydroxylase; 4-hydroxyphenylpyruvic acid dioxygenase. Enzyme Commission Number: EC 1.13.11.27. CAS No. 9029-72-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0546; 4-hydroxyphenylpyruvate dioxygenase; EC 1.13.11.27; 9029-72-5; p-hydroxyphenylpyruvic hydroxylase; p-hydroxyphenylpyruvate hydroxylase; p-hydroxyphenylpyruvate oxidase; p-hydroxyphenylpyruvic oxidase; p-hydroxyphenylpyruvate dioxygenase; p-hydroxyphenylpyruvic acid hydroxylase; 4-hydroxyphenylpyruvic acid dioxygenase. Cat No: EXWM-0546.
4-sulfobenzoate 3,4-dioxygenase
A system, containing a reductase which is an iron-sulfur flavoprotein (FMN), an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Group: Enzymes. Synonyms: 4-sulfobenzoate dioxygenase; 4-sulfobenzoate 3,4-dioxygenase system. Enzyme Commission Number: EC 1.14.12.8. CAS No. 122933-81-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0696; 4-sulfobenzoate 3,4-dioxygenase; EC 1.14.12.8; 122933-81-7; 4-sulfobenzoate dioxygenase; 4-sulfobenzoate 3,4-dioxygenase system. Cat No: EXWM-0696.
5-nitrosalicylate dioxygenase
The enzyme, characterized from the soil bacterium Bradyrhizobium sp. JS329, is involved in the pathway of 5-nitroanthranilate degradation. It is unusual in being able to catalyse the ring fission without the requirement for prior removal of the nitro group. The product undergoes spontaneous lactonization, with concurrent elimination of the nitro group. Group: Enzymes. Synonyms: naaB (gene name); 5-nitrosalicylate:oxygen 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.64. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0584; 5-nitrosalicylate dioxygenase; EC 1.13.11.64; naaB (gene name); 5-nitrosalicylate:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0584.
5-pyridoxate dioxygenase
A flavoprotein. Group: Enzymes. Synonyms: 5-pyridoxate oxidase; 5-pyridoxate,NADPH:oxygen oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.14.12.5. CAS No. 37256-70-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0694; 5-pyridoxate dioxygenase; EC 1.14.12.5; 37256-70-5; 5-pyridoxate oxidase; 5-pyridoxate,NADPH:oxygen oxidoreductase (decyclizing). Cat No: EXWM-0694.
7,8-dihydroxykynurenate 8,8a-dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: 7,8-dihydroxykynurenate oxygenase; 7,8-dihydroxykynurenate 8,8α-dioxygenase; 7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.10. CAS No. 9029-58-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0530; 7,8-dihydroxykynurenate 8,8a-dioxygenase; EC 1.13.11.10; 9029-58-7; 7,8-dihydroxykynurenate oxygenase; 7,8-dihydroxykynurenate 8,8α-dioxygenase; 7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing). Cat No: EXWM-0530.
8'-apo-β-carotenoid 14',13'-cleaving dioxygenase
A thiol-dependent enzyme isolated from rat and rabbit. Unlike EC 1.13.11.63, β-carotene-15,15'-dioxygenase, it is not active towards β-carotene. The secondary product has not been characterized, but may be (3E,5E)-7-hydroxy-6-methylhepta-3,5-dien-2-one. Group: Enzymes. Synonyms: 8'-apo-β-carotenol:O2 oxidoreductase (14',13'-cleaving). Enzyme Commission Number: EC 1.13.11.67. CAS No. 198028-39-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0587; 8'-apo-β-carotenoid 14',13'-cleaving dioxygenase; EC 1.13.11.67; 198028-39-6; 8'-apo-β-carotenol:O2 oxidoreductase (14',13'-cleaving). Cat No: EXWM-0587.
8'-apo-carotenoid 13,14-cleaving dioxygenase
Isolated from the bacterium Novosphingobium aromaticivorans. It is less active with 4'-apo-β-carotenal and γ-carotene. Group: Enzymes. Synonyms: NACOX1 (gene name). Enzyme Commission Number: EC 1.13.11.82. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0603; 8'-apo-carotenoid 13,14-cleaving dioxygenase; EC 1.13.11.82; NACOX1 (gene name). Cat No: EXWM-0603.
9-cis-β-carotene 9',10'-cleaving dioxygenase
Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza. Group: Enzymes. Synonyms: CCD7 (gene name); MAX3 (gene name); NCED7 (gene name). Enzyme Commission Number: EC 1.13.11.68. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0588; 9-cis-β-carotene 9',10'-cleaving dioxygenase; EC 1.13.11.68; CCD7 (gene name); MAX3 (gene name); NCED7 (gene name). Cat No: EXWM-0588.
9-cis-epoxycarotenoid dioxygenase
Requires iron(II). Acts on 9-cis-violaxanthin and 9'-cis-neoxanthin but not on the all-trans isomers. In vitro, it will cleave 9-cis-zeaxanthin. Catalyses the first step of abscisic-acid biosynthesis from carotenoids in chloroplasts, in response to water stress. The other enzymes involved in the abscisic-acid biosynthesis pathway are EC 1.1.1.288 (xanthoxin dehydrogenase), EC 1.2.3.14 (abscisic-aldehyde oxidase) and EC 1.14.13.93 [(+)-abscisic acid 8'-hydroxylase]. Group: Enzymes. Synonyms: nine-cis-epoxycarotenoid dioxygenase; NCED; AtNCED3; PvNCED1; VP14. Enzyme Commission Number: EC 1.13.11.51. CAS No. 199877-10-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0570; 9-cis-epoxycarotenoid dioxygenase; EC 1.13.11.51; 199877-10-6; nine-cis-epoxycarotenoid dioxygenase; NCED; AtNCED3; PvNCED1; VP14. Cat No: EXWM-0570.
acireductone dioxygenase [iron(II)-requiring]
Requires iron(II). If Ni2+ is bound instead of iron(II), the reaction catalysed by EC 1.13.11.53, acireductone dioxygenase (Ni2+-requiring), occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Enzyme Commission Number: EC 1.13.11.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0573; acireductone dioxygenase [iron(II)-requiring]; EC 1.13.11.54; ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Cat No: EXWM-0573.
acireductone dioxygenase (Ni2+-requiring)
Requires Ni2+. If iron(II) is bound instead of Ni2+, the reaction catalysed by EC 1.13.11.54, acireductone dioxygenase [iron(II)-requiring], occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Enzyme Commission Number: EC 1.13.11.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0572; acireductone dioxygenase (Ni2+-requiring); EC 1.13.11.53; ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Cat No: EXWM-0572.
Requires Fe2+. Group: Enzymes. Synonyms: anthranilate hydroxylase; anthranilic hydroxylase; anthranilic acid hydroxylase. Enzyme Commission Number: EC 1.14.12.1. CAS No. 9059-17-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0678; anthranilate 1,2-dioxygenase (deaminating, decarboxylating); EC 1.14.12.1; 9059-17-0; anthranilate hydroxylase; anthranilic hydroxylase; anthranilic acid hydroxylase. Cat No: EXWM-0678.
benzene 1,2-dioxygenase
A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase and ferredoxin. Requires Fe2+. Group: Enzymes. Synonyms: benzene hydroxylase; benzene dioxygenase. Enzyme Commission Number: EC 1.14.12.3. CAS No. 9075-66-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0692; benzene 1,2-dioxygenase; EC 1.14.12.3; 9075-66-5; benzene hydroxylase; benzene dioxygenase. Cat No: EXWM-0692.
benzoate 1,2-dioxygenase
A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase. Requires Fe2+. Group: Enzymes. Synonyms: benzoate hydroxylase; benzoate hydroxylase; benzoic hydroxylase; benzoate dioxygenase; benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating) [incorrect]. Enzyme Commission Number: EC 1.14.12.10. CAS No. 9059-18-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0679; benzoate 1,2-dioxygenase; EC 1.14.12.10; 9059-18-1; benzoate hydroxylase; benzoate hydroxylase; benzoic hydroxylase; benzoate dioxygenase; benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating) [incorrect]. Cat No: EXWM-0679.
β-carotene 15,15'-dioxygenase
Requires Fe2+. The enzyme cleaves β-carotene symmetrically, producing two molecules of all-trans-retinal. Both atoms of the oxygen molecule are incorporated into the products. The enzyme can also process β-cryptoxanthin, 8'-apo-β-carotenal, 4'-apo-β-carotenal, α-carotene and γ-carotene in decreasing order. The presence of at least one unsubstituted β-ionone ring in a substrate greater than C30 is mandatory. A prokaryotic enzyme has been reported from the uncultured marine bacterium 66A03, where it is involved in the proteorhodopsin system, which uses retinal as its chromophore. Group: Enzymes. Synonyms: blh (gene name); BCO1 (gene name); BCDO (gene name); carotene dioxygenase; carotene 15,15'-dioxygenase; BCMO1 (misleading); β-carotene 15,15'-monooxygenase (incorrect). Enzyme Commission Number: EC 1.13.11.63. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0583; β-carotene 15,15'-dioxygenase; EC 1.13.11.63; blh (gene name); BCO1 (gene name); BCDO (gene name); carotene dioxygenase; carotene 15,15'-dioxygenase; BCMO1 (misleading); β-carotene 15,15'-monooxygenase (incorrect). Cat No: EXWM-0583.
biphenyl-2,3-diol 1,2-dioxygenase
Contains Fe2+ or Mn2+. This enzyme participates in the degradation pathway of biphenyl and PCB (poly chlorinated biphenyls), and catalyses the first ring cleavage step by incorporating two oxygen atoms into the catechol ring formed by EC 1.3.1.56, cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase.The enzyme from the bacterium Burkholderia xenovorans LB400 can also process catechol, 3-methylcatechol, and 4-methylcatechol, but less efficiently. The enzyme from the carbazole-degrader Pseudomonas resinovorans strain CA10 also accepts 2'-aminobiphenyl-2,3-diol. The enzyme from Ralstonia sp. SBUG 290 can also accept 1,2-dihydroxydibenzofuran and 1,2-dihydroxynaphthalene. The enzyme is strongly inhibited by the substrate.Not identical with EC 1.13.11.2 catechol 2,3-dioxygenase. Group: Enzymes. Synonyms: 2,3-dihydroxybiphenyl dioxygenase; biphenyl-2,3-diol dioxygenase; bphC (gene name); biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyc. Enzyme Commission Number: EC 1.13.11.39. CAS No. 103679-58-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0558; biphenyl-2,3-diol 1,2-dioxygenase; EC 1.13.11.39; 103679-58-9; 2,3-dihydroxybiphenyl dioxygenase; biphenyl-2,3-diol dioxygenase; bphC (gene name); biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0558.
biphenyl 2,3-dioxygenase
Requires Fe2+. The enzyme from Burkholderia fungorum LB400 (previously Pseudomonas sp.) is part of a multicomponent system composed of an NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske-type iron-sulfur cluster and a catalytic mononuclear nonheme iron centre. Chlorine-substituted biphenyls can also act as substrates. Similar to the three-component enzyme systems EC 1.14.12.3 (benzene 1,2-dioxygenase) and EC 1.14.12.11 (toluene dioxygenase). Group: Enzymes. Synonyms: biphenyl dioxygenase. Enzyme Commission Number: EC 1.14.12.18. CAS No. 103289-55-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0687; biphenyl 2,3-dioxygenase; EC 1.14.12.18; 103289-55-0; biphenyl dioxygenase. Cat No: EXWM-0687.
caffeate 3,4-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing). This enzyme participates in phenylpropanoid biodegradation. Group: Enzymes. Synonyms: 3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.22. CAS No. 37256-61-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0541; caffeate 3,4-dioxygenase; EC 1.13.11.22; 37256-61-4; 3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing). Cat No: EXWM-0541.
carbazole 1,9a-dioxygenase
This enzyme catalyses the first reaction in the pathway of carbazole degradation. The enzyme attacks at the 1 and 9a positions of carbazole, resulting in the formation of a highly unstable hemiaminal intermediate that undergoes a spontaneous cleavage and rearomatization, resulting in 2'-aminobiphenyl-2,3-diol. In most bacteria the enzyme is a complex composed of a terminal oxygenase, a ferredoxin, and a ferredoxin reductase. The terminal oxygenase component contains a nonheme iron centre and a Rieske [2Fe-2S] iron-sulfur cluster. Group: Enzymes. Synonyms: CARDO. Enzyme Commission Number: EC 1.14.12.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0689; carbazole 1,9a-dioxygenase; EC 1.14.12.22; CARDO. Cat No: EXWM-0689.
carotenoid-9',10'-cleaving dioxygenase
Requires Fe2+. The enzyme catalyses the asymmetric oxidative cleavage of carotenoids. The mammalian enzyme can also cleave all-trans-lycopene. Group: Enzymes. Synonyms: BCO2 (gene name); β-carotene 9',10'-monooxygenase (misleading); all-trans-β-carotene:O2 oxidoreductase (9',10'-cleaving). Enzyme Commission Number: EC 1.13.11.71. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0591; carotenoid-9',10'-cleaving dioxygenase; EC 1.13.11.71; BCO2 (gene name); β-carotene 9',10'-monooxygenase (misleading); all-trans-β-carotene:O2 oxidoreductase (9',10'-cleaving). Cat No: EXWM-0591.
catechol 1,2-dioxygenase
Requires Fe3+. Involved in the metabolism of nitro-aromatic compounds by a strain of Pseudomonas putida. Group: Enzymes. Synonyms: catechol-oxygen 1,2-oxidoreductase; 1,2-pyrocatechase; catechase; catechol 1,2-oxygenase; catechol dioxygenase; pyrocatechase; pyrocatechol 1,2-dioxygenase; CD I; CD II. Enzyme Commission Number: EC 1.13.11.1. CAS No. 9027-16-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0529; catechol 1,2-dioxygenase; EC 1.13.11.1; 9027-16-1; catechol-oxygen 1,2-oxidoreductase; 1,2-pyrocatechase; catechase; catechol 1,2-oxygenase; catechol dioxygenase; pyrocatechase; pyrocatechol 1,2-dioxygenase; CD I; CD II. Cat No: EXWM-0529.
catechol 2,3-dioxygenase
Requires FeII. The enzyme initiates the meta-cleavage pathway of catechol degradation. Group: Enzymes. Synonyms: 2,3-pyrocatechase; catechol 2,3-oxygenase; catechol oxygenase; metapyrocatechase; pyrocatechol 2,3-dioxygenase; xylE (gene name); catechol:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.2. CAS No. 9029-46-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0539; catechol 2,3-dioxygenase; EC 1.13.11.2; 9029-46-3; 2,3-pyrocatechase; catechol 2,3-oxygenase; catechol oxygenase; metapyrocatechase; pyrocatechol 2,3-dioxygenase; xylE (gene name); catechol:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0539.
chloridazon-catechol dioxygenase
An iron protein, requiring additional Fe2+. Not identical with EC 1.13.11.1 (catechol 1,2-dioxygenase), EC 1.13.11.2 (catechol 2,3-dioxygenase) or EC 1.13.11.5 (homogentisate 1,2-dioxygenase). Involved in the breakdown of the herbicide chloridazon. Group: Enzymes. Synonyms: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.36. CAS No. 82869-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0555; chloridazon-catechol dioxygenase; EC 1.13.11.36; 82869-32-7; 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0555.
cysteamine dioxygenase
A non-heme iron protein that is involved in the biosynthesis of taurine. Requires catalytic amounts of a cofactor-like compound, such as sulfur, sufide, selenium or methylene blue for maximal activity. 3-Aminopropanethiol (homocysteamine) and 2-mercaptoethanol can also act as substrates, but glutathione, cysteine, and cysteine ethyl- and methyl esters are not good substrates. Group: Enzymes. Synonyms: persulfurase; cysteamine oxygenase;cysteamine:oxygen oxidoreductase. Enzyme Commission Number: EC 1.13.11.19. CAS No. 9033-41-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0538; cysteamine dioxygenase; EC 1.13.11.19; 9033-41-4; persulfurase; cysteamine oxygenase;cysteamine:oxygen oxidoreductase. Cat No: EXWM-0538.
cysteine dioxygenase
Requires Fe2+ and NAD(P)H. Group: Enzymes. Synonyms: cysteine oxidase. Enzyme Commission Number: EC 1.13.11.20. CAS No. 37256-59-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0540; cysteine dioxygenase; EC 1.13.11.20; 37256-59-0; cysteine oxidase. Cat No: EXWM-0540.
The enzyme from the aerobic bacterium Ralstonia sp. U2 donates electrons to both EC 1.14.12.12, naphthalene 1,2-dioxygenase and EC 1.14.13.172, salicylate 5-hydroxylase. The enzyme from Pseudomonas NCIB 9816 is specific for the ferredoxin associated with naphthalene dioxygenase; it contains FAD and a [2Fe-2S] cluster. Group: Enzymes. Synonyms: NADH-ferredoxin(NAP) reductase. Enzyme Commission Number: EC 1.18.1.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1112; ferredoxin-NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific); EC 1.18.1.7; NADH-ferredoxin(NAP) reductase. Cat No: EXWM-1112.
flavanone 3-dioxygenase
Requires Fe2+ and ascorbate. Group: Enzymes. Synonyms: naringenin 3-hydroxylase; flavanone 3-hydroxylase; flavanone 3β-hydroxylase; flavanone synthase I; (2S)-flavanone 3-hydroxylase; naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). Enzyme Commission Number: EC 1.14.11.9. CAS No. 75991-43-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0677; flavanone 3-dioxygenase; EC 1.14.11.9; 75991-43-4; naringenin 3-hydroxylase; flavanone 3-hydroxylase; flavanone 3β-hydroxylase; flavanone synthase I; (2S)-flavanone 3-hydroxylase; naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). Cat No: EXWM-0677.
gallate dioxygenase
Contains non-heme Fe2+. The enzyme is a ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Group: Enzymes. Synonyms: GalA. Enzyme Commission Number: EC 1.13.11.57. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0576; gallate dioxygenase; EC 1.13.11.57; GalA. Cat No: EXWM-0576.
γ-butyrobetaine dioxygenase
Requires Fe2+ and ascorbate. Group: Enzymes. Synonyms: α-butyrobetaine hydroxylase; γ-butyrobetaine hydroxylase; butyrobetaine hydroxylase. Enzyme Commission Number: EC 1.14.11.1. CAS No. 9045-31-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0625; γ-butyrobetaine dioxygenase; EC 1.14.11.1; 9045-31-2; α-butyrobetaine hydroxylase; γ-butyrobetaine hydroxylase; butyrobetaine hydroxylase. Cat No: EXWM-0625.
gentisate 1,2-dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: gentisate oxygenase; 2,5-dihydroxybenzoate dioxygenase; gentisate dioxygenase; gentisic acid oxidase; gentisate:oxygen 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.4. CAS No. 9029-48-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0559; gentisate 1,2-dioxygenase; EC 1.13.11.4; 9029-48-5; gentisate oxygenase; 2,5-dihydroxybenzoate dioxygenase; gentisate dioxygenase; gentisic acid oxidase; gentisate:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0559.
gibberellin 2β-dioxygenase
Also acts on a number of other gibberellins. Group: Enzymes. Synonyms: gibberellin 2β-hydroxylase. Enzyme Commission Number: EC 1.14.11.13. CAS No. 85713-20-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0629; gibberellin 2β-dioxygenase; EC 1.14.11.13; 85713-20-8; gibberellin 2β-hydroxylase. Cat No: EXWM-0629.
gibberellin 3β-dioxygenase
Requires Fe2+ and ascorbate. Group: Enzymes. Synonyms: gibberellin 3β-hydroxylase; (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3β-hydroxylating). Enzyme Commission Number: EC 1.14.11.15. CAS No. 120860-89-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0631; gibberellin 3β-dioxygenase; EC 1.14.11.15; 120860-89-1; gibberellin 3β-hydroxylase; (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3β-hydroxylating). Cat No: EXWM-0631.
gibberellin-44 dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: oxygenase, gibberellin A44 oxidase; (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase. Enzyme Commission Number: EC 1.14.11.12. CAS No. 112198-85-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0628; gibberellin-44 dioxygenase; EC 1.14.11.12; 112198-85-3; oxygenase, gibberellin A44 oxidase; (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase. Cat No: EXWM-0628.
homogentisate 1,2-dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: homogentisicase; homogentisate oxygenase; homogentisate dioxygenase; homogentisate oxidase; homogentisic acid oxidase; homogentisic acid oxygenase; homogentisic oxygenase; homogentisate:oxygen 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.5. CAS No. 9029-49-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0568; homogentisate 1,2-dioxygenase; EC 1.13.11.5; 9029-49-6; homogentisicase; homogentisate oxygenase; homogentisate dioxygenase; homogentisate oxidase; homogentisic acid oxidase; homogentisic acid oxygenase; homogentisic oxygenase; homogentisate:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0568.
hydroquinone 1,2-dioxygenase
The enzyme is an extradiol-type dioxygenase, and is a member of the nonheme-iron(II)-dependent dioxygenase family. It catalyses the ring cleavage of a wide range of hydroquinone substrates to produce the corresponding 4-hydroxymuconic semialdehydes. Group: Enzymes. Synonyms: hydroquinone dioxygenase; benzene-1,4-diol:oxygen 1,2-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.66. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0586; hydroquinone 1,2-dioxygenase; EC 1.13.11.66; hydroquinone dioxygenase; benzene-1,4-diol:oxygen 1,2-oxidoreductase (decyclizing). Cat No: EXWM-0586.
hydroxyquinol 1,2-dioxygenase
An iron protein. Highly specific; catechol and pyrogallol are acted on at less than 1% of the rate at which hydroxyquinol is oxidized. Group: Enzymes. Synonyms: hydroxyquinol dioxygenase; benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing); benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (ring-opening). Enzyme Commission Number: EC 1.13.11.37. CAS No. 91847-14-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0556; hydroxyquinol 1,2-dioxygenase; EC 1.13.11.37; 91847-14-2; hydroxyquinol dioxygenase; benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing); benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (ring-opening). Cat No: EXWM-0556.
hyoscyamine (6S)-dioxygenase
Requires Fe2+ and ascorbate. Group: Enzymes. Synonyms: hyoscyamine 6β-hydroxylase; hyoscyamine 6β-dioxygenase; hyoscyamine 6-hydroxylase. Enzyme Commission Number: EC 1.14.11.11. CAS No. 103865-33-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0627; hyoscyamine (6S)-dioxygenase; EC 1.14.11.11; 103865-33-4; hyoscyamine 6β-hydroxylase; hyoscyamine 6β-dioxygenase; hyoscyamine 6-hydroxylase. Cat No: EXWM-0627.
hypoxia-inducible factor-asparagine dioxygenase
Contains iron, and requires ascorbate. Catalyses hydroxylation of an asparagine in the C-terminal transcriptional activation domain of HIF-α, the α subunit of the transcriptional regulator HIF (hypoxia-inducible factor), which reduces its interaction with the transcriptional coactivator protein p300. The requirement of oxygen for the hydroxylation reaction enables animals to respond to hypoxia. Group: Enzymes. Synonyms: HIF hydroxylase. Enzyme Commission Number: EC 1.14.11.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0648; hypoxia-inducible factor-asparagine dioxygenase; EC 1.14.11.30; HIF hydroxylase. Cat No: EXWM-0648.
hypoxia-inducible factor-proline dioxygenase
Contains iron, and requires ascorbate. Specifically hydroxylates a proline residue in HIF-α, the α subunit of the transcriptional regulator HIF (hypoxia-inducible factor), which targets HIF for proteasomal destruction.The requirement of oxygen for the hydroxylation reaction enables animals to respond to hypoxia. Group: Enzymes. Synonyms: HIF hydroxylase. Enzyme Commission Number: EC 1.14.11.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0646; hypoxia-inducible factor-proline dioxygenase; EC 1.14.11.29; HIF hydroxylase. Cat No: EXWM-0646.
indole 2,3-dioxygenase
Enzymes from the plants Tecoma stans, Jasminum grandiflorum and Zea mays are flavoproteins containing copper. They are part of enzyme systems that form either anthranil (2,1-benzoisoxazole) (Tecoma stans), anthranilate (Jasminum grandiflorum) or both (Zea mays) as the final product. A second enzyme from Tecoma stans is not a flavoprotein, does not require copper, and is part of a system that forms anthranilate as the final product. Group: Enzymes. Synonyms: indole oxidase; indoleamine 2,3-dioxygenase (ambiguous); indole:O2 oxidoreductase; indole-oxygen 2,3-oxidoreductase (decyclizing); IDO (ambiguous); indole:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.17. CAS No. 37256-57-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0536; indole 2,3-dioxygenase; EC 1.13.11.17; 37256-57-8; indole oxidase; indoleamine 2,3-dioxygenase (ambiguous); indole:O2 oxidoreductase; indole-oxygen 2,3-oxidoreductase (decyclizing); IDO (ambiguous); indole:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0536.
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