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DL-Dithiothreitol. Synonyms: threo-1,4-Dimercapto-2,3-butanediol, Clelands reagent, DTT. CAS No. 3483-12-3. Pack Sizes: 1, 5, 10, 25, 100 g in poly bottle. Product ID: CDC10-0048. Molecular formula: C4H10O2S2. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; DL-Dithiothreitol; CDC10-0048; 3483-12-3; C4H10O2S2; threo-1,4-Dimercapto-2,3-butanediol, Clelands reagent, DTT; 222-468-7; MFCD00004877; 3483-12-3. Purity: ≥98%. Color: White. EC Number: 222-468-7. Physical State: Powder. Solubility: H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow. Quality Level: 200. Storage: 2-8°C. Boiling Point: 125 °C. Melting Point: 41-44 °C (lit.). Density: 1.04 g/mL at 20 °C. Product Description: An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N'-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Typically, a seven fold lower concentration of DTT (100 mM) is needed than is used for 2-mercaptoethanol (5% v/v, 700 mM).
DL-Dithiothreitol-d10
98 atom % D, 98% (CP). Group: Fluorescence/luminescence spectroscopy.
1,4-Dithio-DL-threitol
Reagent for the quantitative reduction of disulfide group. Prevents the oxidation of cholecystokinin during its extraction from brain and duodenal tissues. Cleavage of disulfide bonds in proteins. Uses: Used as a reagent in biochemistry to prevent oxidation of thiol groups and to reduce disulfides to dithiols; has been used as a radioprotectant; dithiothreitol (dtt) is the common name for a small-molecule redox reagent known as cleland's reagent. Synonyms: DL-1,4-Dithiothreitol; DTT; Cleland's reagent; threo-1,4-Dimercapto-2,3-butanediol; Dithiothreitol; dl-Dithiothreitol; 1,4-Dithiothreitol; D-Dtt; 1,4-Dithio-dl-threitol; DL-Dithiothreitol; threo-1,4-Dimercapto-2,3-butanediol. Grades: ≥ 99 % (Assay by titration). CAS No. 3483-12-3. Molecular formula: C4H10O2S2. Mole weight: 154.25.
Dithiothreitol (DTT)
Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland's reagent. DTT's oxidized form is a disulfide-bonded 6-membered ring. Its name derives from the four-carbon sugar, threose. DTT has an epimeric ('sister') compound, dithioerythritol (DTE).DTT is an unusually strong reducing agent, owing to its high conformational propensity to form a six-membered ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of a typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions and is illustrated below. The intermediate mixed-disulfide state is unstable (i.e., poorly populated) because the...ting."DTT is frequently used to reduce the disulfide bonds of proteins and, more generally, T... Group: Biochemicals. Alternative Names: Cleland's reagent;; (2R,3R)-rel-1,4-Dimercapto-2,3-butanediol; (±)-1,4-Dimercapto-2,3-butanediol; (±)-Dithiothreitol; 1,4-Dithio-DL-threitol; 1,4-Dithiothreitol; DL-1,4-Dimercapto-2,3-dihydroxybutane; DL-1,4-Dithiothreitol; DL-Dithiothreitol; Sputolysin; WR 34678; threo-1,4-Dimercapto-2,3-butanediol; threo-2,3-Dihydroxy-1,4-butanedithiol; threo-2,3-Dihydroxy-1,4-dithiolbutane. Grades: Molecular Biology Grade. CAS No. 3483-12-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C4H10O2S2, Molecular Weight: 154.24. US Biological Life Sciences.
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