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DOTAP is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. DOTAP is a good immunomodulator, the antigen presenting capacity of antigen presenting cells can be obviously improved by preparing cationic liposome by packaging polypeptide or protein antigens and the DOTAP, and the DOTAP can activate the antigen presenting cells through a mitogen-activated protein kinase (MAP) pathway to induce specific immune response, unlike the traditional adjuvant which activates the antigen presenting cells through a Toll-like receptor pathway. Synonyms: 1,2-Dioleoyloxy-3-(trimethylammonium)propane; 1,2-Dotap; N,N,N-Trimethyl-2,3-bis((-1-oxo-octadecenyl)oxy)-(Z,Z)-1-propanaminium; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium. CAS No. 113669-21-9. Molecular formula: C42H80NO4. Mole weight: 663.09.
DOTAP chloride
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride. CAS No. 132172-61-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-112754A.
DOTAP:Chol (50:50) Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP:Chol:DOPE (10:75:5) Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP:DOPC (1:99)-ATP Liposome
This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP:DOPC (20:80)-ATP Liposome
This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP:DOPC (5:95)-ATP Liposome
This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
This product is a positively charged PEGylated ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP:DOPE (50:50) Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
DOTAP mesylate
DOTAP mesylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 252769-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W127426.
DOTAP methylsulfate
DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate. CAS No. 144189-73-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-W127378.
DOTAP:PC:Chol (10:60:30)-ATP Liposome
This product is a positively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
0.5% DiI Encapsulated DOTAP Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
0.5% DiO Encapsulated DOTAP Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
1,2-dioleoyloxy-3-(trimethylammonium)propane (DOTAP) chloride has been used for the preparation of cationic liposome and liposome-DNA complex. It has also been used to assess tumor necrosis factor α (TNF-α) production. Synonyms: Dotap chloride; DOTAP-Cl; DOTAP (chloride); 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-, chloride (1:1); 1,2-Dioleoyl-3-trimethylammonium-propane, Chloride; (+/-)-Dotap chloride; Dotap chloride, (+/-)-; N-(1-(2,3-Dioleoyloxy)propyl)-N,N,N-trimethylammonium chloride; (2,3-dioleoyloxy-propyl)-trimethylammonium-chloride; 18:1 TAP (DOTAP), 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt), chloroform; DOTAP Chloride; N,N,N-Trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanaminium; 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium. Grades: >98% by HPLC. CAS No. 132172-61-3. Molecular formula: C42H80ClNO4. Mole weight: 698.54.