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DOTMA DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 104872-42-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-139200. MedChemExpress MCE
DOTMA DOTMA is one of the first cationic lipid used for gene transfection. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome. Synonyms: 1,2-Di-O-Octadecenyl-3-Trimethylammonium Propane; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium. Grades: >98%. CAS No. 104872-42-6. Molecular formula: C42H84ClNO2. Mole weight: 670.57. BOC Sciences 9
DOTMA DOTMA is one of the first cationic lipid used for gene transfection. DOTMA is an effective transfection agent in vitro and in vivo. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DOTMA; 1,2-di-O-octadecenyl-3-trimethylammonium propane. Product Category: Others. Appearance: Solid powder. CAS No. 104872-42-6. Molecular formula: C42H84ClNO2. Mole weight: 670.59. Purity: >98%. IUPACName: N,N,N-trimethyl-2,3-bis(((Z)-octadec-9-en-1-yl)oxy)propan-1-aminium chloride. Canonical SMILES: CCCCCCCC/C=C\CCCCCCCCOCC(OCCCCCCCC/C=C\CCCCCCCC)C[N+](C)(C)C.[Cl-]. Product ID: ACM104872426. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
DOTMA:Chol (50:50) Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
DOTMA:DOPE (50:50) Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
DOTMA Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
0.5% DiI Encapsulated DOTMA Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
0.5% DiO Encapsulated DOTMA Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
0.5% NBD-DOPE Encapsulated DOTMA:Chol (50:50) Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
0.5% NBD-DOPE Encapsulated DOTMA:DOPE (50:50) Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
0.5% Rhod-PE Encapsulated DOTMA:Chol (50:50) Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
0.5% Rhod-PE Encapsulated DOTMA:DOPE (50:50) Liposomes Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs

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