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| Product | Description | |
|---|---|---|
| Anti-Cancer Approved Drug Library | A unique collection of 1726 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); - These FDA, EMA, or NMPA approved anti-cancer drugs have annotated bioactivity, safety, and bioavailability; - Effective tool for cancer research and drug repurposing screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. , in lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2110. Categories: Anti-Cancer Approved Drug Libraries. |  |
| Anti-Cancer Drug Library | A unique collection of 2478 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials), an effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug repositioning drug discovery; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc; involved in 15 different cancer research areas, such as lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2150. Categories: Anti-Cancer Drug Libraries. | |
| Approved Drug Library | A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), etc; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, GPCR/G protein, Neuroscience, Membrane Transporter/Ion Channel, Microbiology & Virology, Immunology/Inflammation, Tyrosine Kinase/Adaptors, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1000. Categories: Approved Drug Libraries. | |
| Chemotherapy Drug Library | 51 Chemotherapeutic drugs that can be used for high-throughput and high-content screening. - Includes common chemotherapy drugs such as paclitaxel, cyclophosphamide, cytarabine, doxorubicin, etc. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure, high purity and reduce the false-positive rates. Uses: Scientific use. Product Category: L2151. Categories: Chemotherapy Drug Libraries. | |
| Drug-Fragment Library | Quantity: 1159 drug fragments?a must-have tool for FBDD; - Physiochemical properties: 53% of fragments are Ro3 compliant?and all fragments matching with approved drugs or clinical compounds will have the best drug potential; - Quality guaranteed: NMR and HPLC/LCMS validated to ensure high purity and quality; - Applicable to various detection methods: suitable for SPR, NMR, and X-ray crystallization screening. Uses: Scientific use. Product Category: L8800. Categories: Drug-Fragment Libraries. | |
| Drug-induced Liver Injury (DILI) Compound Library | A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening?- Include anti-cancer drugs, antibiotics, antituberculotic agents, antiretrovirals, antiepileptic agents, and cardiac medications, etc. ?- Diversified in toxicities: Steatosis, Mitochondrial toxicity, cholestasis, drug allergy (hypersensitivity), etc. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5510. Categories: Drug-induced Liver Injury (DILI) Compounds Libraries. | |
| Drug Metabolite/Impurity Library | A unique collection of 200 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS); - Structurally diverse, medicinally active, and cell permeable; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5800. Categories: Drug Metabolite/Impurity Libraries. | |
| Drug Repurposing Compound Library | A unique collection of 4240 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS); - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary; - Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc. - Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc. - Detailed compound information with structure, target, activity, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9200. Categories: Drug Repurposing Compounds Libraries. | |
| FDA-Approved Drug Library | A unique collection of 1729 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research evidence and clinical trials; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas: oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc- Structurally diverse, medicinally active, and cell permeable; - Rich documentation with structure, target, IC50 value and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity. Uses: Scientific use. Product Category: L4200. Categories: FDA-Approved Drug Libraries. | |
| FDA-Approved & Pharmacopeia Drug Library | 3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by FDA, EMA, PMDA, NMPA, etc. or included in pharmacopoeia such as USP, BP, JP, etc. ; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, Neuroscience, Immunology/Inflammation, respiratory system disease, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1010. Categories: FDA-Approved & Pharmacopeia Drug Libraries. | |
| Pediatric Drug Library | A unique collection of 1015 pediatric drugs for high-throughput screening and high-content screening. - All drugs are either approved for marketing or in clinical trials with validated biological activity and safety. - Can be used for functional repositioning of drugs to discover new pediatric indications. - Detailed instructions, compound structures, target information, activity descriptions, etc. - NMR and HPLC detection techniques to ensure high product purity. - All compounds are available in stock. Uses: Scientific use. Product Category: L9210. Categories: Pediatric Drug Libraries. | |
| RO5 Drug-like Natural Product Library | 2743 is a collection of natural products that meet the "Lipinski's Rule of Five" and have high potential for drug discovery. - Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more. - Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories. - Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives. Uses: Scientific use. Product Category: L6160. Categories: RO5 Drug-like Natural Product Libraries. | |
| Targeted Therapy Drug Library | 116 tumor-targeted drugs that can be used for high-throughput and high-content screening. - Targets include EGFR, VEGFR, c-Met, Bcr-Abl, HER2, etc. - All compounds have known and good biological activity, safety and bioavailability. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure, high purity and reduce the false-positive rates. Uses: Scientific use. Product Category: L2152. Categories: Targeted Therapy Drug Libraries. | |
| Cysteine Covalent Library | The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. In recent years, covalent chemical probes have become an important tool for drug discovery. A large number of successful applications in the evaluation of protein druggability, especially the successful application of Cys residues, bring hope for the discovery and synthesis of new covalently modified compounds. To this end, we designed a cysteine-specific covalent library. The electrophilic "warhead" of the fragments is acrylamide or chloroacetamide (25% and 75% of the library, respectively). These functional groups were chosen to construct the library because they are in the "best position" for reactivity and show selectivity in chemical proteomics screening. Uses: Scientific use. Product Category: L9411. Categories: Cysteine Covalent Libraries. | |
| Golden Scaffold Library | Diversity: Selected from 1, 600, 000 drug-like compounds, 10000 compounds representing 5000 scaffolds selected from a large drug-like chemical source?- Drug-likeness: filtering out reactive, toxic and otherwise undesirable structural motifs, and removing compounds that demonstrate a broad promiscuous activity (PAINS); - Strict quality control: more than 90% purity for each member with HNMR/LCMS validation?- Cost effective: Liquid small package is available. (Can be purchased together with Mini scaffolds library?forming a diversity library with more broad coverage. ). Uses: Scientific use. Product Category: L5610. Categories: Golden Scaffold Libraries. | |
| High Solubility 3D Diversity Fragment Library | Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this context, Fragment-based drug design (FBDD) came into being. Organic synthesis can transform miniature hits into effective lead compounds. The deficiencies in the current screening of compound libraries usually result in the need for a large amount of synthetic investment to achieve multi-directional fragment growth, which limits the efficiency of the mini-fragment hit modification process. To meet this challenge, we designed a library of highly soluble 3D structural diversity fragments. The utility of X-ray-based fragment screening and the ability to achieve rapid analog synthesis: Uses: Scientific use. Product Category: L7850. Categories: High Solubility 3D Diversity Fragment Libraries. | |
| High Solubility Polyfunctional Group Fragment Library | Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this ... are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. The high solubility multifunctional fragment library is designed by analyzing the spatial stability of all commercially available fragments and selecting a chemically diverse subset. In order to enhance the diversity of the compound library, we carefully selected some additional saturated heterocyclic compounds to supplement the compound library. Uses: Scientific use. Product Category: L7810. Categories: High Solubility Polyfunctional Group Fragment Libraries. | |
| Mini Electrophilic Heterocyclic Fragment Library | The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. Targeted covalent inhibitors and chemical probes have become part of drug discovery methods. Given the advantages of fragment-based drug discovery, screening electrophilic fragments has become a promising alternative to discover and verify new targets and generate viable chemical starting points, even for targets that are almost difficult to handle. In response to this situation, we designed a small library of heterocyclic electrophilic compounds. General technology for covalent fragment screening ?. Uses: Scientific use. Product Category: L7860. Categories: Mini Electrophilic Heterocyclic Fragment Libraries. | |
| SQ109 | SQ109 is a novel antitubercular drug. It was screened out from a big chemical library designed around the active pharmacophore of ethambutol (EMB). SQ109 displayed potent activity against all the substrains of Mtb including XDR- and MDR-TB clinical strains. Synonyms: SQ109; SQ-109; SQ 109; NSC 722041; NSC-722041; NSC722041. Grades: >98%. CAS No. 502487-67-4. Molecular formula: C22H38N2. Mole weight: 330.55. |  |
| 1,2,3,4-Tetra-O-benzyl-6-O-triisopropylsilyl-b-D-galactopyranose | 1,2,3,4-Tetra-O-benzyl-6-O-triisopropylsilyl-b-D-galactopyranose, a complex carbohydrate compound, is extensively employed in synthetic drug development and drug candidate discovery. This elusive molecule aids in the production of glycan libraries and glycopeptides, facilitating the investigation of carbohydrate-protein interactions implicated in the pathogenesis of malignant neoplasms and viral infections. Molecular formula: C43H56O6Si. Mole weight: 697.01. | |
| Adrenergic Receptor-Targeted Compound Library | A unique collection of 219 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2700. Categories: Adrenergic Receptor-Targeted Compounds Libraries. | |
| Angiogenesis related Compound Library | A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries. | |
| Anti-Alzheimer's Disease Compound Library | A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. - Targets include tau protein, γ Secretase, 5-HT Receptor, BACE, etc. - Some of them are FDA approved. - Structurally diverse, medicinally active, and cell permeable; - Detailed information about compound structure, target, activity, IC50, etc. - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9840. Categories: Anti-Alzheimer's Disease Compounds Libraries. | |
| Anti-Bacterial Compound Library | A unique collection of 921 antibacterial bioactive compounds, a powerful tool for antibacterial drug development; - Includes various antibiotics and antibacterial bioactive compounds with unique structures; - Detailed information about compound structure, target, activity, etc. ; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4520. Categories: Anti-Bacterial Compounds Libraries. | |
| Antibiotics Library | A unique collection of 708 compounds with antibiotic activity for new antibacterial drug screening; - Most of them are approved to be marketed, and some of which are FDA approved. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4400. Categories: Antibiotics Libraries. | |
| Anti-Breast Cancer Compound Library | A unique collection of 1436 compounds with anti-breast cancer therapeutic activity or targeting breast cancerÂ’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study?- Targets include HER-2, VEGF, EGFR, PARP, CDK4/6, HSP, PD-1, SET7/9, BRCA, etc. ?- Some compounds have been in market or in clinical trials; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2191. Categories: Anti-Breast Cancer Compounds Libraries. | |
| Anti-Cancer Active Compound Library | A unique collection of 2114 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2160. Categories: Anti-Cancer Active Compounds Libraries. | |
| Anti-Cancer Clinical Compound Library | A unique collection of 1990 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); - Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers; - Effective tool for cancer research and drug repurposing screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. , in lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2120. Categories: Anti-Cancer Clinical Compounds Libraries. | |
| Anti-Cancer Compound Library | A unique collection of 5885 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials); - Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2100. Categories: Anti-Cancer Compounds Libraries. | |
| Anti-Cancer Library Plus | Quantity: well-chosen 1468 anti-tumor compounds with unique structures; - High antitumor activity: 99% of compounds with IC50 below 3 μM; - Covers 42 tumor related targets with each compound having clear target; - Detailed information: each compound has information about activity testing method, providing reference for your experimental design; - HNMR/LCMS validated to ensure high purity and quality; - A supplemental tool for anticancer drug development and target identification. Uses: Scientific use. Product Category: L2180. Categories: Anti-Cancer Libraries Plus. | |
| Anti-Cancer Metabolism Compound Library | A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Covers 16 major targets related to cancer cellular metabolism (glucose, proteins, lipids and nucleic acids) including ACL, CA, FASN, GLUT, GLS, HMG-CoA, MAGL, MCTs, PDH, PDK, PKM, etc. ; Effect tool for research in cancer metabolism and anti-cancer drug screening. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2130. Categories: Anti-Cancer Metabolism Compounds Libraries. | |
| Anti-COVID-19 Traditional Chinese Medicine Compound Library | A unique collection of 1162 monomers from 70 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening?- Sources are 70 TCM plants including Lonicera japonica Thunb. , Forsythia suspensa, Scutellaria baicalensis Georgi, Bupleuri Radix, Agastache rugosa, Isatidis Radix, Rhodiola rosea, etc. ?- Structurally diverse: including Flavonoids, alkaloids, Polyphenols, Terpenes, ets. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6720. Categories: Anti-COVID-19 Traditional Chinese Medicine Compounds Libraries. | |
| Anti-Fungal Compound Library | A unique collection of 253 antifungal compounds effective for drug repurposing screening, combination screening and biological investigation. - Contains antifungal agents to treat tinea corporis and Candidiasis, and compounds inhibiting the fungal-specific targets. - Bioactivity and safety confirmed by clinical research and trials, some of which are FDA approved; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4500. Categories: Anti-Fungal Compounds Libraries. | |
| Anti-Infection Compound Library | A unique collection of 2977 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; - Effective tool for new anti-infective drugs high throughput screening and high content screening, containing sulfonamides, tetracyclines, aminoglycosides, and macrolide derivatives, etc. - Bioactivity and safety confirmed by clinical research and trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1800. Categories: Anti-Infection Compounds Libraries. | |
| Anti-Inflammatory Traditional Chinese Medicine Compound Library | A collection of 1040 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study?- Covers various targets such as COX, CCR, STAT, TGFβ, etc. involved in inflammation?- Diversity: includes Flavone, Saponins, Terpenes, Alkaloids, etc. ?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6710. Categories: Anti-Inflammatory Traditional Chinese Medicine Compounds Libraries. | |
| Anti-Lung Cancer Compound Library | A unique collection of 1566 compounds with anti-lung cancer therapeutic activity or targeting lung cancerÂ’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study?- Targets include EGFR, PI3K, FGFR, HER2, ALK, c-Met, etc. ?- Some compounds have been in market or in clinical trials; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2190. Categories: Anti-Lung Cancer Compounds Libraries. | |
| Anti-Nervous System Disease Library | Quantity: well-chosen 1246 compounds with unique structures targeting nervous system; - High bioactivity: All compounds with IC50 below 3. 5 μM; - Covers 52 nervous system disease related targets with each compound having clear target; - Detailed information: each compound has information about activity testing method, providing reference for your experimental design; - A supplemental tool for nervous system disease drug development and target identification. Uses: Scientific use. Product Category: L4660. Categories: Anti-Nervous System Disease Libraries. | |
| Antioxidant Compound Library | A unique collection of 1040 antioxidant bioactive small molecule compounds for high-throughput, high-content screening. - Targets include mTOR, Keap1-Nrf2, ROS, NF-κB, etc. - Structural diversity, significant drug potency with cell permeability. - Detailed instruction manual, compound structure, target information, activity description, etc. - Multiple detection techniques such as NMR and HPLC/LCMS to ensure the accurate structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L2910. Categories: Antioxidant Compounds Libraries. | |
| Anti-Parasitic Compound Library | A selection of 336 compounds with anti-parasitic activity, a powerful tool for anti-parasitic drug development. - Contains a wide range of compounds with anti-parasitic activity, including anti-Plasmodium, anti-Leishmania, and anti-filariasis etc. - Detailed instructions, compound structure, target information, activity description, etc. - Multiple assays such as NMR, HPLC/LCMS to ensure correct product structure, high purity and to reduce false positives. Uses: Scientific use. Product Category: L4510. Categories: Anti-Parasitic Compounds Libraries. | |
| Anti-Parkinson's Disease Compound Library | A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. - Targets include Dopamine Receptor, COMT, MAO-B, 5-HT Receptor, etc. - Some of them are FDA approved. - Structurally diverse, medicinally active, and cell permeable; - Detailed information about compound structure, target, activity, IC50, etc. - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9830. Categories: Anti-Parkinson's Disease Compounds Libraries. | |
| Anti-Tumor Natural Product Library | A unique collection of 1471 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Known bioactivity for all compounds: detailed biological and pharmacological information, providing the research foundation and theoretical direction for screening; - Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Cost-effectiveness: expensive natural products with poor drug likeliness are excluded, allowing for more high-quality natural products at a lower cost. Uses: Scientific use. Product Category: L6700. Categories: Anti-Tumor Natural Product Libraries. | |
| Anti-Virus Compound Library | Quantity: A unique collection of 800 anti-virus compounds effective for new anti-virus drugs high throughput screening and high content screening; - Target viruses include HBV, HCV, HIV, HSV, Influenza Virus, Reverse Transcriptase, etc. covering more than 140 targets; - Structurally diverse and strong bioactivity; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description, providing reference for your experimental design; - NMR and HPLC/LCMS validated to ensure high purity and quality. - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1700. Categories: Anti-Virus Compounds Libraries. | |
| Anti-virus Traditional Chinese Medicine Monomer Library | A collection of 270 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies. Uses: Scientific use. Product Category: L6730. Categories: Anti-virus Traditional Chinese Medicine Monomer Libraries. | |
| Apoptosis Compound Library | A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; - Targets include Bcl-2, Caspase, p53, TNF-alpha, and surviving, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9000. Categories: Apoptosis Compounds Libraries. | |
| Autophagy Compound Library | A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3200. Categories: Autophagy Compounds Libraries. | |
| Bioactive Compound Library | A collection of 11585 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification; - All compounds have clear targets; - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - Covers various disease research areas, such as Cancer, Metabolism, Immunology and Cardiovascular system, etc. - Detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4000. Categories: Bioactive Compounds Libraries. | |
| Bioactive Compounds Library Max | A collection of 19703 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification. - All compounds are described with corresponding target information, which makes activity studies more evidence-based. - An effective tool for drug repurposing and cell-induced target screening. - Covers multiple areas of disease studies, such as cancer, metabolism, immune system and cardiovascular system. - Detailed instructions, compound structures, target information, activity descriptions, etc. - Structural diversity, significant drug potency and cell penetration. Uses: Scientific use. Product Category: L4010. Categories: Bioactive Compounds Libraries Max. | |
| Carboxylic Acid Fragment Library With Solubility | Solubility is one of the fundamental physicochemical properties of drug candidates, and early assessment of solubility properties can better interpret in vitro results and provide valuable information for the design of new molecules. Compounds with low solubility often produce erroneous results during functional assays, thus increasing the risk of obtaining false hits or leads. Measuring solubility at an early stage of the drug discovery process can identify potentially ambiguous activity data, such as false negatives due to poor solubility. The high solubility and good theoretical membrane permeability of soluble carboxylic acid fragment molecules can better address the limiting factors in drug discovery. Features:- (1) Soluble carboxylic acid fragment compounds: 1509. - (2) Soluble fluorinated carboxylic acid fragment molecules: 122. - (3) Soluble diverse carboxylic acid fragment molecules: 103. - (4) Highly soluble carboxylic acid fragment molecules: 352. Uses: Scientific use. Product Category: L7870. Categories: Carboxylic Acid Fragment Libraries With Solubility. | |
| Clinical Compound Library | A unique collection of 3142 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS); - All compounds have been permitted into clinical trial phases, categorized into Phase 1, Phase 2 and Phase 3. - An effective tool for new drug screening and cell differentiation induction; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3400. Categories: Clinical Compounds Libraries. | |
| CNS-Penetrant Compound Library | A unique collection of 516 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include Kinases, GPCR, and ion channels, etc. ; - Effective tool for drug screening in brain disorders, such as brain tumor, mental disorders, and neurodegenerative diseases, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable and CNS penetrant; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5900. Categories: CNS-Penetrant Compounds Libraries. | |
| Covalent Natural Product Library | Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening. - Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research. - Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information. - Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost. - Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc. Uses: Scientific use. Product Category: L6150. Categories: Covalent Natural Product Libraries. | |
| Cytokine Inhibitor Library | A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and most of them are approved to be marketed; - Targets cover various cytokines including IL, CSF, IFN, TNF, TGF-beta family, growth factors, chemokine family, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3600. Categories: Cytokine Inhibitor Libraries. | |
| DNA Damage and Repair Compound Library Plus | Quantity: well-chosen 667 compounds with unique structures targeting DNA damage & repair; - High bioactivity: All compounds with IC50 below 3 μM; - Targets included 19 DNA damage & repair related proteins; - Detailed information: each compound has information about activity testing method, providing reference for your experimental design; - HNMR/LCMS validated to ensure high purity and quality; - A powerful tool for DNA damage/repair targeting drug development and target identification. Uses: Scientific use. Product Category: L3980. Categories: DNA Damage and Repair Compounds Libraries Plus. | |
| Endocrinology-Hormone Library | A unique collection of 813 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Targets include Estrogen receptor, thyroid hormone receptor, Adrenergic receptors, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2400. Categories: Endocrinology-Hormone Libraries. | |
| Epigenetics Compound Library | Quantity: well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; - Targets include HDAC, SIRT, HAT, and HMT, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description, providing reference for your experimental design; - NMR and LCMS/HPLC validated to ensure high purity and quality. - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1200. Categories: Epigenetics Compounds Libraries. | |
| Featured Novel Bioactive Compound Library | Well-chosen quantity: only contains 990 bioactive compounds after careful selection; - Cover diversified species: virus, bacterial, parasite, etc. ; - Uniqueness in structure: less studied with greater research space and values than classic bioactive compound structures; - Diversified targets: covering 235 targets, including different levels of targets, such as single protein, cell, tissue, etc. ; - Detailed compound information about activity testing method; - Powerful tool for drug discovery and target identification. Uses: Scientific use. Product Category: L4150. Categories: Featured Novel Bioactive Compounds Libraries. | |
| Ferroptosis Compound Library | A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study?- Covers various targets such as GPX4, ROS, p53, Nrf2, etc. ?- Some compounds are FDA approved; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8700. Categories: Ferroptosis Compounds Libraries. | |
| Fmoc-L-(2,6-di-Me)Tyr-OH | Fmoc-2,6-dimethyl-L-tyrosine is a derivative of L-tyrosine, which is one of the 20 naturally occurring amino acids. It is an acronym for 9-Fluorenylmethyloxycarbonyl-2,6-dimethyltyrosine. Fmoc-2,6-dimethyl-L-tyrosine is also referred to as fluorenylmethoxycarbonyl-2,6-dimethyltyrosine or Fmoc-Dmt-OH. Fmoc-Dmt-OH has a molecular weight of 393.45 and a molecular formula of C23H21NO5. Uses: Fmoc-2,6-dimethyl-l-tyrosine has several research applications, including the synthesis of peptides, proteins, and peptidomimetics. it is also used as a building block of combinatorial libraries for the discovery of new drug candidates. fmoc-2,6-dimethyl-l-tyrosine has been incorporated into various bioactive peptides and proteins to improve their stability, activity, and specificity. it has also been used as a precursor for the synthesis of novel peptidomimetics with potential therapeutic applications. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine, Fmoc-2,6-dimethyl-L-tyrosine, (S)-N-Fmoc-2,6-Dimethyltyrosine. CAS No. 206060-54-0. Molecular formula: C26H25NO5. Mole weight: 431.5. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid. Canonical SMILES: CC1=CC (=CC (=C1CC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C)O. Density: 1.290 g/cm3. Catalog: ACM206060540. |  |
| GPCR Compound Library | A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; - Potential to find new GPCR drug candidates by screening against orphan GPCRs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include 5-HT receptor, dopamine receptor, opioid receptor, adrenergic receptor, mGluR, Cannabinoid receptor, ETA-receptor, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1500. Categories: GPCR Compounds Libraries. | |
| GPCR Compound Library Plus | Quantity: well-chosen 338 GPCR targeting compounds with unique structures; - High bioactivity: All compounds with IC50 below 3. 5 μM; - Targets include 21 various GPCR subtypes; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - HNMR/LCMS validated to ensure high purity and quality; - A powerful tool for GPCR drug development and target identification. Uses: Scientific use. Product Category: L1580. Categories: GPCR Compounds Libraries Plus. | |
| Hematopoietic Toxicity Compound Library | A unique collection of 101 compounds with defined hematopoietic toxicity for high throughput and high content drug screening; - Targets include HDAC, PPAR, DNA Alkylating, EGFR, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3100. Categories: Hematopoietic Toxicity Compounds Libraries. | |
| HIF-1 Signaling Pathway Compound Library | A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies?- Covers PI3K-AKT, MAPK, Ubiquitination signaling pathways and targets such as HIF, HIF Prolyl-Hydroxylase, E1/E2/E3 Enzyme, PI3K, MAPK, Proteasome, etc. - Part of them are in clinical trial phase or FDA approved?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8500. Categories: HIF-1 Signaling Pathway Compounds Libraries. | |
| High Solubility FragLite Fragment Library | The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. The FragLites identify productive drug-like interactions, which are identified sensitively and unambiguously by X-ray crystallography, exploiting the anomalous scattering of the halogen substituent. This mapping of protein interaction surfaces provides an assessment of druggability and can identify efficient start points for the de novo design of hit molecules incorporating the interacting motifs. Combine fragments from FragLites to generate fragment lead compounds: Uses: Scientific use. Product Category: L7840. Categories: High Solubility FragLite Fragment Libraries. | |
| High Solubility Pharmacophore Fragment Library | The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. We analyzed the key interactions discovered by target protein hot spots to derive the fragment pharmacophore represented by the fragment-protein complex available in the PDB. Using this information, we designed a set of minimal diversified commercial fragments, covering most experiments combined with pharmacophore, used to identify the starting point of the fragment for drug discovery targets. Uses: Scientific use. Product Category: L7830. Categories: High Solubility Pharmacophore Fragment Libraries. | |
| Histamine & Melatonin Receptor-Targeted Library | A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3300. Categories: Histamine & Melatonin Receptor-Targeted Libraries. | |
| Human Endogenous Metabolite Library | A unique collection of 1400 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening; - Effective tool for research in endogenous metabolism-related diseases, exploring the tumorigenesis, and drug discovery; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2500. Categories: Human Endogenous Metabolite Libraries. | |
| Human Metabolite Library | A unique collection of 4532 human metabolites for high-throughput, high-content screening. - An effective tool for studying human metabolic diseases, exploring the pathogenesis of cancer and finding new drugs. - Some compounds have been marketed or entered the clinical phase, which ensured low bio-toxicity and high bio-activity. - Structural diversity, significant drug potency and cell permeability. - Detailed specifications, description of compound structures, activity, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L2570. Categories: Human Metabolite Libraries. | |
| Inhibitor Library | A unique collection of 5700 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Covers various major targets including MAPK, PI3K, JAK, HDAC, VEGFR, CDK, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2000. Categories: Inhibitor Libraries. | |
| Ion Channel Inhibitor Library | A unique collection of 946 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include potassium channel, calcium channel, sodium channel, Proton pump, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2300. Categories: Ion Channel Inhibitor Libraries. | |
| Kinase Inhibitor Library | A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include MAPK, PI3K, JAK, STAT, CDK, MEK, Insulin/IGF receptors, CaM Kinease II, PKA, JNK, PKC, RAF, EGFR, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1600. Categories: Kinase Inhibitor Libraries. | |
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