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| Product | Description | |
|---|---|---|
| Encequidar mesylate | Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Encequidar showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). Encequidar is currently under clinical trials. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HM30181; HM-30181; HM 30181; HM-30181 mesylate; Encequidar mesylate. Product Category: Inhibitors. Appearance: White solid powder. CAS No. 849675-87-2. Molecular formula: C39H40N6O10S. Mole weight: 784.84. Purity: >98%. IUPACName: N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide methanesulfonate. Canonical SMILES: O=C(NC1=CC(OC)=C(C=C1C2=NN(N=N2)C3=CC=C(C=C3)CCN4CC5=C(CC4)C=C(C(OC)=C5)OC)OC)C6=CC(C7=C(C=CC=C7)O6)=O.OS(=O)(C)=O. Product ID: ACM849675872. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Encequidar mesylate | Encequidar mesylate (HM30181 mesylate; HM30181A mesylate) is a competitive and potent P-glycoprotein inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM30181 mesylate; HM30181A mesylate. CAS No. 849675-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13646A. |  |
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