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Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV , with an EC 50 of 3.75 nM in HepG2 cell. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS200475 monohydrate; SQ34676 monohydrate. CAS No. 209216-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13623A.
Entecavir monohydrate
Entecavir triphosphate is a highly potent inhibitor of wild-type HBV Pol and is 100- to 300-fold more potent than lamivudine triphosphate against 3TC-resistant HBV Pol. It competes with dGTP to be incorporated into viral DNA. Uses: Antiviral agents. Synonyms: Entecavir (monohydrate); UNII-5968Y6H45M; 5968Y6H45M. Grade: 98%. CAS No. 209216-23-9. Molecular formula: C12H15N5O3.H2O. Mole weight: 295.29.
Entecavir monohydrate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-, hydrate (1:1), Entecavir monohydrate, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-, monohydrate (9CI).
Entecavir Monohydrate
A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B. It has a role as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral drug. Alternative Names: Entecavir hydrate. entecavir monohydrate. Entecavir (monohydrate). Entecavir hydrate (JAN). CAS No. 209216-23-9. Product ID: API209216239. Molecular formula: C12H17N5O4. Mole weight: 295.29. EINECS: 606-668-5. SMILES: C=C1C(CC(C1CO)O)N2C=NC3=C2N=C(NC3=O)N.O. Appearance: White Powder. Category: Antivirus APIs.
2-amino-9-((1R,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one is an impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Synonyms: 3-Epi-Entecavir; Entecavir 3-epimer; UNII-FD1LY3K97F; FD1LY3K97F; 2-Amino-9-[(1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one; 2-Amino-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one; 9-((1S,3S,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine; 2-Amino-1,9-dihydro-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-; Entecavir 3-epimer [USP]; SCHEMBL2670719; AMY38952; ENTECAVIR 3-EPIMER [USP IMPURITY]; ENTECAVIR MONOHYDRATE IMPURITY B [EP IMPURITY]; 1333204-93-5; 2-Amino-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one; Rel-2-amino-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3,9-dihydro-6H-purin-6-one. CAS No. 1333204-93-5. Molecular formula: C12H15N5O3. Mole weight: 277.28.
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