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Product | Description | |
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1-[N-[N-(2-Aminobenzoyl)glycyl]-4-nitro-L-phenylalanyl]-L-proline Quick inquiry Where to buy Suppliers range | It is a substrate for the fluorescent assay of angiotensin I-converting enzyme and of the bacterial dipeptidyl carboxypeptidase from Escherichia coli. Synonyms: 2-Aminobenzoylglycyl-4-nitrophenylalanyl-proline; Abz-Gly-p-nitro-Phe-Pro-OH; L-Proline,N-(2-aminobenzoyl)glycyl-4-nitro-L-phenylalanyl-; o-Aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline. CAS No. 67482-93-3. Molecular formula: C23H25N5O7. Mole weight: 483.47. | |
2,4-Dinitrophenyl 2-Deoxy-2-fluoro-β-D-galactoside Quick inquiry Where to buy Suppliers range | Fluorinated and deoxygenated glycosides as mechanistic probes of Escherichia coli (lacZ) β-galactosidase. By use of the slow substrate 2,4-dinitrophenyl-2-deoxy-2-fluoro-β-D-galactopyranoside, a glycosyl enzyme intermediate has been trapped on the enzyme. Glu-268 was identified as the catalytic nucleophile of human lysosomal β-galactosidase precursor. Synonyms: 2,4-Dinitrophenyl 2-Deoxy-2-fluoro-β-D-galactopyranoside. Grades: 98%. CAS No. 143716-62-5. Molecular formula: C12H13FN2O9. Mole weight: 348.24. | |
4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside is an intricate fluorogenic substrate commonly utilized for comprehensive detection of microbial enzymes. Specifically, the substrate facilitates the identification of Escherichia coli and Salmonella Typhimurium through monitoring the hydrolization of N-acetylglucosamine, a vital facet of bacterial cell walls. The advantageous emission of fluorophores when this substrate is cleaved by the aforementioned enzymes reinforces its effectiveness in resistance determination and ailment diagnosis. Synonyms: 4-Methylumbelliferyl N-acetyl-b-D-glucosaminide; 4-MU-GlcNAc; GlcNAc-b-4MU; 2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-b-D-glucopyranosyl]oxy]-4-methyl-. Grades: ≥98%. CAS No. 37067-30-4. Molecular formula: C18H21NO8. Mole weight: 379.36. | |
Ciprofloxacin Hydrochloride 10mg/ml Quick inquiry Where to buy Suppliers range | Ciprofloxacin Hydrochloride is a high activity fluoroquinolone antibiotic effective against a broad spectrum of gram positive and negative bacteria such as Pseudomonas, Salmonella, streptococcus and Staphylococcus. Effective against mycoplasma (12 days). Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position. The bactericidal action of ciprofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Ciprofloxacin has been shown to be active against most strains of the following organisms:Gram-Positive Bacteria:Enterococcus faecalis (Many strains are only moderately susceptible); Staphylococcus haemolyticus; Staphylococcus hominis; Staphylococcus saprophyticus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes.Gram-Negative Bacteria:Acinetobacter calcoaceticus subs. anitratus; Acinetobacter calcoaceticus subs. Iwoffi; Aeromonas caviae; Aeromonas hydrophila; Brucella melitensis; Campylobacter coli; Campylobacter jejuni; Citrobacter diversus; Citrobacter freundii; Edwardsiella tarda; Enterobacter aerogenes; Enterobacter cloacae; Escherichia coli; Haemophilus ducreyi; Haemophilus influenzae; Haemophilus parainfluenzae; Klebsiella oxytoca; Klebsiella pneumoniae; Legionella pneumophila; Moraxella (Branhamella) catarrhalis; Morganella morganii; Neisseria gonorrhoeae; Neisseria meningitidis; Pasteurella multocida; Proteus mirabilis; Proteus vulgaris; Providencia rettgeri; Providencia stuartii; Pseudomonas aeruginosa; Salmonella enteritidis; Salmonella typhi; Serratia marcescens; Shigella flexneri; Shigella sonnei; Vibrio cholerae; Vibrio parahaemolyticus; Vibrio vulnificus; Yersinia enterocolitica. Other Organisms:Chlamydia trachomatis (only moderately susceptible); Mycobacterium tuberculosis (only moderately susceptible).Also Available:C5074: Ciprofloxacin Hydrochloride. Group: Biochemicals. Alternative Names: Sterile-filtered aqueous solution. Grades: Molecular Biology Grade. CAS No. 86393-32-0. Pack Sizes: 10ml, 5x10ml. Molecular Formula: C17H18FN3O3 HCl H2O, Molecular Weight: 385.8. US Biological Life Sciences. | Worldwide |
Ciprofloxacin Hydrochloride, Monohydrate Quick inquiry Where to buy Suppliers range | Ciprofloxacin Hydrochloride is a high activity fluoroquinolone antibiotic effective against a broad spectrum of gram positive and negative bacteria such as Pseudomonas, Salmonella, streptococcus and Staphylococcus. Effective against mycoplasma (12 days). Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position. The bactericidal action of ciprofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Ciprofloxacin has been shown to be active against most strains of the following organisms:Gram-Positive Bacteria:Enterococcus faecalis (Many strains are only moderately susceptible); Staphylococcus haemolyticus; Staphylococcus hominis; Staphylococcus saprophyticus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes.Gram-Negative Bacteria:Acinetobacter calcoaceticus subs. anitratus; Acinetobacter calcoaceticus subs. Iwoffi; Aeromonas caviae; Aeromonas hydrophila; Brucella melitensis; Campylobacter coli; Campylobacter jejuni; Citrobacter diversus; Citrobacter freundii; Edwardsiella tarda; Enterobacter aerogenes; Enterobacter cloacae; Escherichia coli; Haemophilus ducreyi; Haemophilus influenzae; Haemophilus parainfluenzae; Klebsiella oxytoca; Klebsiella pneumoniae; Legionella pneumophila; Moraxella (Branhamella) catarrhalis; Morganella morganii; Neisseria gonorrhoeae; Neisseria meningitidis; Pasteurella multocida; Proteus mirabilis; Proteus vulgaris; Providencia rettgeri; Providencia stuartii; Pseudomonas aeruginosa; Salmonella enteritidis; Salmonella typhi; Serratia marcescens; Shigella flexneri; Shigella sonnei; Vibrio cholerae; Vibrio parahaemolyticus; Vibrio vulnificus; Yersinia enterocolitica. Other Organisms:Chlamydia trachomatis (only moderately susceptible); Mycobacterium tuberculosis (only moderately susceptible).Also Available:C5075: Ciprofloxacin Hydrochloride 10mg/ml. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid Hydrochloride; Bay Q3939 Hydrochloride. Grades: Molecular Biology Grade. CAS No. 86393-32-0. Pack Sizes: 1g, 10g, 25g, 50g. Molecular Formula: C17H18FN3O3 HCl H2O, Molecular Weight: 385.8. US Biological Life Sciences. | Worldwide |
Methyl-D-erythritol-d3 Phosphate Quick inquiry Where to buy Suppliers range | A labeled substrate for terpenoid biosynthesis; terpenoid biosynthesis enzyme Escherichia. Group: Biochemicals. Alternative Names: (2S,3R)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Tretazicar Quick inquiry Where to buy Suppliers range | Tretazicar (CB1954) is a dinitrobenzamide prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. CB1954 has been proposed for use in enzyme-prodrug gene therapy systems with the Escherichia coli enzyme nitroreductase (Ntr). Ntr converts CB1954 to 2- and 4-hydroxylamino derivatives, whereupon the non-enzymatic reaction of the 4-hydroxylamino derivative with cellular thio- esters generates a potent cytotoxic bifunctional alkylating agent capable of cross-linking DNA. Ntr delivery has been achieved in vitro using retroviral and adenoviral vectors and confirmed by immunocytochemical demonstration of Ntr expression. The Ntr-expressing cells have been shown to be sensitized to CB1954 by up to 2000-fold. The Ntr-CB1954 system shows effective bystander killing in mixed populations of Ntr-expressing and non-expressing cells treated with CB1954. The efficacy of this enzyme-prodrug approach in model systems compared with other VDEPT approaches demonstrates the feasibility and future promise of this gene therapy strategy. Uses: Antineoplastic agents. Synonyms: CB1954; CB-1954; CB 1954; Tretazicar. Grades: 0.98. CAS No. 21919-05-1. Molecular formula: C9H8N4O5. Mole weight: 252.186. |