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Product | Description | |
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2,3-bis(4-Nitrophenyl)-5-phenyltetrazolium Chloride Quick inquiry Where to buy Suppliers range | 2,3-bis(4-Nitrophenyl)-5-phenyltetrazolium Chloride was used as a substrate for electron transfer mediator-cyclodextrin inclusion compounds for colorimetry using redox enzymes. Group: Biochemicals. Grades: Highly Purified. CAS No. 69231-13-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H13N6O4+; Cl-, Molecular Weight: 389.343545. US Biological Life Sciences. | Worldwide |
2,6-Dichlorophenolindophenyl acetate Quick inquiry Where to buy Suppliers range | 2,6-Dichlorophenolindophenyl acetate, a prominent biochemical, holds substantial significance in determining ascorbic acid concentrations. Its multidimensional application extends to serving as a redox indicator to detect biomarkers of various viruses and diseases in enzyme-linked immunosorbent assays (ELISA). Synonyms: DIPA; 4-[(2,3-dichloro-4-oxocyclohexa-2,5-dien-1-yl)imino]phenyl acetate. CAS No. 24857-20-3. Molecular formula: C14H9Cl2NO3. Mole weight: 310.13. | |
3-Acetylpyridine adenine dinucleotide Quick inquiry Where to buy Suppliers range | 3-Acetylpyridine adenine dinucleotide is a pivotal cofactor in metabolic regulation, exhibiting intricate involvement in diverse biological reactions. Its functionality as an electron carrier fortifies numerous enzymatic reactions, facilitating the intercellular transfer of energy and electrons. Consequently, the compound assuming a vital role in cellular respiration and ATP research and development. Moreover, its application encompasses the exploration of cellular redox reactions, energy transfer mechanisms, in addition to studying a plethora of ailments and pharmaceutical developments. Synonyms: APAD. Grades: 92%. CAS No. 86-08-8. Molecular formula: C22H28N6O14P2. Mole weight: 662.44. | |
4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic Acid (Methoxatin, Pyrroloquinoline, PQQ) Quick inquiry Where to buy Suppliers range | A cofactor of microbial quinoprotein enzyme, and imidazopyrroline. A redox/cofactor found in a a class of enzymes called quinoproteins. Group: Biochemicals. Alternative Names: Methoxatin, Pyrroloquinoline, PQQ. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
β-NADH, Reduced Disodium Salt (Nicotinamide Adenine Dinucleotide) Quick inquiry Where to buy Suppliers range | Beta-nicotinamide adenine dinucleotide hydrate. Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes.NAD is a coenzyme formed from the nucleotide, nicotinamide, adenosine monophosphateand a phosphate group joining the first two components. NADP has the same structure with the addition of an extra phosphate group to AMP. NAD can be reduced to NADH during coupling with reactions which oxidize various organic substrates. For example, the reaction catalyzed by glyceraldehyde phosphate dehydrogenase during glycolysis. NADH then passes to the inside of mitochondria where it donates the electrons it is carrying to the electron transport chain. In this manner, NAD acts as an intermediate energy storage compound that indirectly generates ATP. Generally, NADP accepts electrons from catabolic reactions to form NADPH. An example is its coupling with the conversion of glucose-6-phosphate to ribose-5-phosphate in the pentose phosphate pathway. NADPH has a slightly different role to NADH in that it does not donate electrons to the electron transport chain. Instead, it tends to reduce intermediates in anabolic pathways e.g. fatty acid synthesis. NAD participates in many redox reactions in cells, including those in glycolysis and most of those in the citric acid cycle of cellular respiration. Nicotinamide adenine dinucleotide (NAD) and its relative nicotinamide adenine dinucleotide phosphate (NADP) are two of the most important coenzymes in the cell. In cells, most oxidations are accomplished by the removal of hydrogen atoms. Both of these coenzymes play crucial roles in this. Each molecule of NAD+ (or NADP+) can acquire two electrons; that is, be reduced by two electrons. However, only one proton accompanies the reduction. The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium. Group: Biochemicals. Alternative Names: β-DPNH; β-NADH; DPNH; Diphosphopyridine nucleotide, reduced form; NADH. Grades: Highly Purified. CAS No. 606-68-8. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C21H27N7O14P2Na2, Molecular Weight: 709.41. US Biological Life Sciences. | Worldwide |
β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate Quick inquiry Where to buy Suppliers range | β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(Trihydrogen Diphosphate), P'?5'-Ester with 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium Hydroxide Sodium Salt Hydrate; Adenine-nicotinamide Dinucleotide Sodium Salt Hydrate; CO-I Sodium Salt Hydrate; Codehydrase I Sodium Salt Hydrate; Codehydrogenase I Sodium Salt Hydrate; Coenzyme I Sodium Salt Hydrate; Cozymase I Sodium Salt Hydrate; DPN Sodium Salt Hydrate; Diphosphopyridine Nucleotide Sodium Salt Hydrate; Enzopride Sodium Salt Hydrate; NAD Sodium Salt Hydrate; NAD+ Sodium Salt Hydrate; NSC 20272 Sodium Salt Hydrate; Nadide Sodium Salt Hydrate; Nicotinamide-adenine Dinucleotide Sodium Salt Hydrate; Oxidized diphosphopyridine Nucleotide Sodium Salt Hydrate; β-Diphosphopyridine Nucleotide Sodium Salt Hydrate; β-NAD Sodium Salt Hydrate; β-NAD+ Sodium Salt Hydrate. Grades: 95%. Molecular formula: C21H26N7NaO14P2 X(H2O). Mole weight: 685.41. | |
b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate Quick inquiry Where to buy Suppliers range | b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate exemplifies an essential coenzyme that assumes a pivotal function in diverse biochemical reactions. This compound emerges as uniquely advantageous towards interrogating cellular metabolism, enzyme kinetics and redox reactions. Synonyms: coenzyme II; b-NADP-K; Triphosphopyridine nucleotide potassium salt; TPN; [5-(6-aminopurin-9-yl)-3-hydroxy-4-(oxyphosphinyloxyphosphinyl)oxolan-2-yl]met hyl{[5- (3-carbamoylpyridyl)-3, 4-dihydroxyoxolan-2-yl]methoxy} (hydroxyphosphoryl)hydrogen phosphate,potassium salt; Beta-nadp potassium salt; Nadp monopotassium salt. Grades: ≥ 90%. CAS No. 68141-45-7. Molecular formula: C21H27KN7O17P3. Mole weight: 781.50. | |
Coelenterazine Quick inquiry Where to buy Suppliers range | Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.1 The oxidation of coelenterazine to coelenteramide is accompanied by emission of blue light (emission maximum, 460-470 nm). Luciferase-mediated oxidation of coelenterazine or a derivative is used as an energy donor, typically to a form of green or yellow fluorescent protein, in bioluminescent resonance energy transfer studies.2,3 Alternatively, the calcium-mediated release of coelenterazine from aequorin, followed by non-enzymatic oxidation of this compound, results in bioluminescence. As light emission depends on both calcium and cellular redox status, this reaction is used to non-fluorescently detect changes in calcium level and redox status.4,5. Group: Biochemicals. Alternative Names: 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one; CLZN; Preluciferin; Luciferin; 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one. Grades: Highly Purified. CAS No. 55779-48-1. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 423.46. US Biological Life Sciences. | Worldwide |
Lucanthone Quick inquiry Where to buy Suppliers range | Lucanthone is orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme apurinic-apyrimidinic endonuclease 1 (APEX1 or APE1), with anti-schistosomal and potential antineoplastic activity. Lucanthone intercalates DNA and interferes with the activity of topoisomerases I and II during replication and transcription, thereby inhibiting the synthesis of macromolecules. In addition, this agent specifically inhibits the endonuclease activity of APE1, without affecting its redox activity, resulting in unrepaired DNA strand breaks which may induce apoptosis. Therefore, lucanthone may sensitize tumor cells to radiation and chemotherapy. Furthermore, lucanthone inhibits autophagy through the disruption of lysosomal function. The multifunctional nuclease APE1 is a key component for DNA repair; its expression is often correlated with tumor cell resistance to radio- and chemotherapy. Uses: Schistosomicides. Synonyms: Lucanthonum; 1-{[2-(Diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one; CCRIS 1106. CAS No. 479-50-5. Molecular formula: C20H24N2OS. Mole weight: 340.48. | |
Methoxatin disodium Quick inquiry Where to buy Suppliers range | The disodium salt form of Pyrroloquinoline quinone which is a cofactor related to the enzyme-catalyzed redox reactions glucose and methanol dehydrogenase. Nutritional supplement in health care products. Uses: Microbial Fermentation Products. CAS No. 122628-50-6. Product ID: MFP-011. | |
NADH Thio, Reduced (Nicotinamide Adenine Dinucleotide), Thio-NADH) Quick inquiry Where to buy Suppliers range | Beta-nicotinamide adenine dinucleotide hydrate. Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes.NAD is a coenzyme formed from the nucleotide, nicotinamide, adenosine monophosphateand a phosphate group joining the first two components. NADP has the same structure with the addition of an extra phosphate group to AMP. NAD can be reduced to NADH during coupling with reactions which oxidize various organic substrates. For example, the reaction catalyzed by glyceraldehyde phosphate dehydrogenase during glycolysis. NADH then passes to the inside of mitochondria where it donates the electrons it is carrying to the electron transport chain. In this manner, NAD acts as an intermediate energy storage compound that indirectly generates ATP. Generally, NADP accepts electrons from catabolic reactions to form NADPH. An example is its coupling with the conversion of glucose-6-phosphate to ribose-5-phosphate in the pentose phosphate pathway. NADPH has a slightly different role to NADH in that it does not donate electrons to the electron transport chain. Instead, it tends to reduce intermediates in anabolic pathways e.g. fatty acid synthesis. NAD participates in many redox reactions in cells, including those in glycolysis and most of those in the citric acid cycle of cellular respiration. Nicotinamide adenine dinucleotide (NAD) and its relative nicotinamide adenine dinucleotide phosphate (NADP) are two of the most important coenzymes in the cell. In cells, most oxidations are accomplished by the removal of hydrogen atoms. Both of these coenzymes play crucial roles in this. Each molecule of NAD+ (or NADP+) can acquire two electrons; that is, be reduced by two electrons. However, only one proton accompanies the reduction. The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium. For NAD, the reaction is thus:NAD+ + 2H -> NADH + H+. Group: Biochemicals. Alternative Names: Nicotinamide Adenine Dinucleotide; Thio-NADH; Thionicotinamide adenine dinucleotide. Grades: Highly Purified. CAS No. 1921-48-8. Pack Sizes: 100mg. Molecular Formula: C21H29N7O13SP2, Molecular Weight: 681.51. US Biological Life Sciences. | Worldwide |
Nicotinic Acid Adenine Dinucleotide Quick inquiry Where to buy Suppliers range | Nicotinic Acid Adenine Dinucleotide is an analog of β-Nicotinamide Adenine Dinucleotide; a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(trihydrogen diphosphate), P'?5'-ester with 3-carboxy-1-β-D-ribofuranosylpyridinium, inner salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-pyrophosphate, inner salt; Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, hydroxide, 5'?5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt; 1: PN: WO2006081329 PAGE: 47 claimed sequence; Adenine-nicotinic Acid Dinucleotide; Codehydrogenase I, carboxy deamido analog; Codehydrogenase I, nicotinic acid analog; Deamido-NAD; Deamidodiphosphopyridine Nucleotide; Desamido NAD; Nicotinate Adenine Dinucleotide; Nicotinic Acid-adenine Dinucleotide. CAS No. 6450-77-7. Molecular formula: C21H26N6O15P2. Mole weight: 664.41. | |
PF04191834 Quick inquiry Where to buy Suppliers range | PF04191834 is a novel, potent and selective non-redox 5-lipoxygenase(5-LOX) inhibitor with an IC50 value of 229 +/- 20 nM. It inhibits 5-LOX in human blood cells with an IC80 value of 370 +/- 20 nM. It exhibits good potency in enzyme- and cell-based assays, as well as in a rat model of acute inflammation. It demonstrated approximately 300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and shows no activity toward the cyclooxygenase enzymes. It is effective in inflammation and pain. Uses: Pf04191834 is effective in inflammation and pain. Synonyms: PF-04191834; PF04191834; PF 04191834; PF-4191834; PF4191834; PF 4191834. 4-(3-((4-(1-Methyl-1H-pyrazol-5-yl)phenyl)thio)phenyl)tetrahydro-2H-pyran-4-carboxamide. Grades: >98 %. CAS No. 1029317-21-2. Molecular formula: C22H23N3O2S. Mole weight: 393.51. | |
Pyrroloquinoline quinone disodium salt Quick inquiry Where to buy Suppliers range | The disodium salt form of Pyrroloquinoline quinone which is a cofactor related to the enzyme-catalyzed redox reactions glucose and methanol dehydrogenase. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Methoxatin disodium salt; Methoxatin Disodium; PQQ; Disodium 4,5-dihydro-4,5-dioxo-1H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylate. Grades: 95%. CAS No. 122628-50-6. Molecular formula: C14H4N2Na2O8. Mole weight: 374.17. | |
Riboflavin galactoside Quick inquiry Where to buy Suppliers range | Riboflavin galactoside is a crucial pharmaceutical compound acting as a derivative of riboflavin, known for its role in studying vitamin B2 deficiency. This product acts as a precursor in coenzymes like flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), essential for various enzymatic reactions participating in energy metabolism and cellular redox processes. Molecular formula: C23H30N4O11. Mole weight: 538.50. | |
Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin, Valacidin, Antibiotic RP 5278) Quick inquiry Where to buy Suppliers range | Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an important role in free radical production through redox cycling of NAD(P)H:quinone oxidoreductase (NQO1). Streptonigrin from Streptomyces flocculus is an aminoquinone antitumor antibiotic. Its antineoplastic activity requires reductive activation by Xanthine-converting enzymes. It induces apoptosis by a mechanism involving NF-κB. DNA cleavage reaction and chromosome damage by Streptonigrin are influenced by the nature of the metal ion present and dependent on the production of free radicals. Its antibiotic activity is iron-activated. Group: Biochemicals. Alternative Names: EC Number 223-501-8; 5278RP; AO 50165L302; Abbott Crystalline antibiotic; Bruneomycin; NSC 45383; NSC 56748; NSC 83950; Nigrin; Rufocromomycin; SN; STP; Streptonigran; Streptonigrin; 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic Acid; (4R)-5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-2-pyridinecarboxylic Acid; (R)-Streptonigrin. Grades: Highly Purified. CAS No. 3930-19-6. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 506.46. US Biological Life Sciences. | Worldwide |