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| Product | Description | |
|---|---|---|
| Eosin Y | Eosin Y (Acid Red 87 free base) is a soluble acid red dye molecule. Eosin Y has a wide application in organic synthesis as a photoredox catalyst [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 87 free base. CAS No. 15086-94-9. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-D0505. |  |
| Eosin Y | Eosin Y. Group: Biochemicals. Alternative Names: Acid red 87; C.I. 45380. Grades: Highly Purified. CAS No. 17372-87-1. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C20H6Br4Na2O5. US Biological Life Sciences. |  Worldwide |
| Eosin Y | Eosin Y. Synonyms: 2',4',5',7'-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43. CAS No. 15086-94-9. Pack Sizes: 5, 25 g in glass bottle. Product ID: CDC10-0151. Molecular formula: C20H8Br4O5. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; Eosin Y; CDC10-0151; 15086-94-9; C20H8Br4O5; 2',4',5',7'-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43; MFCD00036189; 15086-94-9. Purity: ~99 %. Physical State: Powder. Solubility: ethanol: 1 mg/mL. Quality Level: 200. Storage: room temp. Boiling Point: 640.3±55.0 °C(Predicted). Melting Point: 300 °C. Density: 1.02 g/mL at 20 °C. |  |
| Eosin y bis(tetrabutylammonium salt) | Heterocyclic Organic Compound. Alternative Names: Eosin Y bis(tetrabutylammonium salt), 123333-95-9. CAS No. 123333-95-9. Molecular formula: C52H78Br4N2O5. Mole weight: 1130.8. Purity: 0.96. IUPACName: 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate;tetrabutylazanium. Canonical SMILES: CCCC[N+] (CCCC) (CCCC)CCCC. CCCC[N+] (CCCC) (CCCC)CCCC. C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. Catalog: ACM123333959. |  |
| Eosin Y (C.I. 45380) | 25g Pack Size. Group: Stains & Indicators. Formula: C20H6Br4Na2O5. CAS No. 17372-87-1. Prepack ID 31787521-25g. Molecular Weight 691.85. See USA prepack pricing. |  |
| Eosin Y disodium salt, Certified ≥93% (Dye content) | Eosin Y disodium salt, Certified ≥93% (Dye content). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eosin Y disodium salt, dye content 85%, indicator | Anti Septic. Group: Acid dyes. Alternative Names: Eosine YB; Phlox Red Toner X-1354; MCULE-3311428648; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-, sodium salt (1:2); CHEBI:52053; I14-18436; MFCD00036189; Eosine J; 7549-EP2277567A1; Certiqual Eosine. CAS No. 17372-87-1. Molecular formula: C20H6Br4Na2O5. Mole weight: 691.859g/mol. IUPACName: disodium;2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. Canonical SMILES: C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. [Na+]. [Na+]. ECNumber: 241-409-6. Catalog: ACM17372871. | |
| Eosin Y disodium salt, dye content 85%, indicator | Eosin Y disodium salt, dye content 85%, indicator. Uses: Anti septic. Group: Xanthene dyes. Alternative Names: Eosine YB; Phlox Red Toner X-1354; MCULE-3311428648; Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-, sodium salt (1:2); CHEBI:52053; I14-18436; MFCD00036189; Eosine J; 7549-EP2277567A1; Certiqual Eosine. CAS No. 17372-87-1. Product ID: disodium; 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. Molecular formula: 691.859g/mol. Mole weight: C20H6Br4Na2O5. C1=CC=C (C (=C1)C2=C3C=C (C (=O)C (=C3OC4=C (C (=C (C=C24)Br)[O-])Br)Br)Br)C (=O)[O-]. [Na+]. [Na+]. InChI=1S/C20H8Br4O5. 2Na/c21-11-5-9-13 (7-3-1-2-4-8 (7)20 (27)28)10-6-12 (22)17 (26)15 (24)19 (10)29-18 (9)14 (23)16 (11)25; ; /h1-6, 25H, (H, 27, 28); ; /q; 2*+1/p-2. SEACYXSIPDVVMV-UHFFFAOYSA-L. |  |
| Eosin Yellowish, 1% Solution, Laboratory Grade, 100 mL | Formula: C20H6Br4Na2O5. Formula Wt: 691. 8. Characteristic: Red-brown crystalline powder. Storage Code: Green; general chemical storage. Group: chem-category biological stains. Alternative Names: Eosin Y, acid red 87. Grades: chem-grade laboratory. CAS No. 17372-87-1. Product ID: 859632. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Eosin Y free acid ≥96% (Dye content) | Eosin Y free acid ≥96% (Dye content). Group: Biochemicals. Grades: Reagent Grade. CAS No. 15086-94-9. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Eosin Y solution | Eosin Y solution. Synonyms: 2',4',5',7'-Tetrabromofluorescein disodium salt, Acid red 87, Eosin yellowish solution. CAS No. 17372-87-1. Pack Sizes: 500 mL in glass bottle. Product ID: CDC10-0152. Molecular formula: C20H6Br4Na2O5. Category: Cosmetic Color Additives. Product Keywords: Cosmetic Ingredients; Cosmetic Color Additives; Eosin Y solution; CDC10-0152; 17372-87-1; C20H6Br4Na2O5; 2',4',5',7'-Tetrabromofluorescein disodium salt, Acid red 87, Eosin yellowish solution; MFCD00005040; 17372-87-1. Purity: 5 wt. % in H2O. Physical State: Liquid. Solubility: H2O: 0.1 g/mL, dark red. Quality Level: 100. Storage: room temp. Application: Eosin Y is suitable for use in hematoxylin and eosin (H&E) staining procedures for various tissue samples like lung nodule and kidney sections. Melting Point: >300°C. Density: 1.015 g/mL at 25 °C. Product Description: Eosin Y, also known as Eosin yellowish is a widely used xanthene dye. It is a counterstain that is used to distinguish between various connective tissue fibers & matrices, and the cytoplasm of different types of cells. Eosin in combination with hematoxylin is useful to demonstrate the general histological architecture of a tissue. | |
| Acidic Mammalian Chitinase Inhibitor, Bisdionin F | A cell-permeable, competitive Acidic Mammalian Chitinase (AMCase) Inhibitor (IC50=0.92uM and Ki=0.42uM for hAMCase, and IC50=2.2uM for mAMCase, in vitro) that demonstrates 20-fold selectivity for hAMCase over hCHIT1. It is shown to decrease chitinase enzymatic activity (5mg/kg, i.p.) in the lungs of control PBS- and OVA-challenged mice. Furthermore, it attenuates lung chitinase activity, reduces eosinophil influx, and improves ventilatory function, in vivo, in a murine model of allergic inflammation. It also causes neutrophilia in the lungs of OVA-challenged mice. Group: Biochemicals. Alternative Names: AMCase Inhibitor, 3,7-dimethyl-1-(3-(3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)propyl)-1H-purine-2,6(3H,7H)-dione. Grades: Highly Purified. CAS No. 917877-86-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AhR Agonist V, VAF347 | A cell-permeable pyrimidinylphenylamine compound that directly and reversibly targets aryl hydrocarbon receptor (AhR) with high-affinity, and induces AhR signaling. Reported to act as an immunomodulator with anti-inflammatory properties. Potently suppresses IgE secretion in B-cells with an IC50 of ~2nM, and inhibits dendritic cells-mediated T-cell proliferation and cytokine production. Further, decreases lung eosinophilia in B-cell-deficient mice, and allergic inflammation. Downregulates PU.1 transcription factor, and impairs human monocytes and Langerhans dendritic cells differentiation. Group: Biochemicals. Alternative Names: ((4-(3-Chloro-phenyl)-pyrimidin-2-yl)-(4-trifluoromethyl-phenyl)-amine). Grades: Highly Purified. CAS No. 574759-62-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClF?N?, Molecular Weight: 349.7. US Biological Life Sciences. | Worldwide |
| AS-35 | AS-35 is used as an antiallergic drug. It controls allergic diseases by inhibiting eosinophil activation. Uses: As-35 is used as an antiallergic drug. Synonyms: AS 35; AS35; AS-35; 3-(1H-Tetrazol-5-yl)-9-[[[2-propyl-3-hydroxy-4-(methylcarbonyl)phenyl]oxy]methyl]-4H-pyrido[1,2-a]pyrimidin-4-one;AS35;4H-Pyrido(1,2-a)pyrimidin-4-one, 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-;9-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one. Grades: >98%. CAS No. 108427-72-1. Molecular formula: C21H20N6O4. Mole weight: 420.42. |  |
| AZ11665362 | AZ11665362 is a potent CRTH2 antagonist. It blocks the migration of eosinophils and basophils, and the rapid mobilization of eosinophils from bone marrow. It might be useful for the treatment of allergic diseases. Uses: Az11665362 might be useful for the treatment of allergic diseases. Synonyms: AZ-11665362; AZ 11665362; AZ11665362; (2,5-Dimethyl-3-(8-methyl-4-quinolinyl)-1H-indol-1-yl)acetic acid. Grades: 98%. CAS No. 629645-40-5. Molecular formula: C22H20N2O2. Mole weight: 344.41. | |
| BMS639623 | BMS639623 is a CCR3 antagonist with picomolar inhibition potency against eosinophil chemotaxis. It may be used for the treatment of asthma. Uses: Bms639623 may be used for the treatment of asthma. Synonyms: BMS-639623; BMS 639623; Urea, N-((1R,2S)-3-((3S)-3-((4-fluorophenyl)methyl)-1-piperidinyl)-2-hydroxy-1-methylpropyl)-N'-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)-. Grades: 98%. CAS No. 675122-44-8. Molecular formula: C25H32FN7O2. Mole weight: 481.57. | |
| BMS 688521 | BMS 688521 is a small molecule antagonist of leukocyte function associated antigen-1 (LFA-1). It has provided proof-of-concept for LFA-1 as an immunological target. BMS 688521 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 2.5 and 78 nM in HUVEC adhesion and mouse specific adhesion assays respectively), which inhibits eosinophil accumulation in the lungs in a mouse allergic eosinophilic lung inflammation model. Synonyms: 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid; BMS-688521; BMS688521; SCHEMBL5392413. Grades: ≥98%. CAS No. 893397-44-9. Molecular formula: C26H19Cl2N5O4. Mole weight: 536.37. | |
| Cetirizine | Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine. It is a racemic selective H1 receptor inverse agonist. It is used in cutaneous mastocytosis. It is used in the treatment of allergies, hay fever, angioedema, and urticaria. It crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. Uses: Cetirizine used in the treatment of allergies, hay fever, angioedema, and urticaria. it crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. it has also been shown to inhibit eosinophil chemotaxis and ltb4 release. Synonyms: Virlix;Cetirizina;Cetryn;2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid. Grades: 95%. CAS No. 83881-51-0. Molecular formula: C21H25ClN2O3. Mole weight: 388.89. | |
| DP2 Antagonist II (CRTH2 Antagonist II, GPR44 Antagonist II, (R)-(5-Chloro-1'-(5-chloro-2-fluorobenzyl)-2,2',5'-trioxospiro(indole-3,3?-pyrrolidin)-1(2H)-yl)acetic Acid) | The (R) enantiomer of a cell-permeable alkynylphenoxyacetic acid that acts as a high affinity antagonist against the G protein-coupled PGD2 receptor CRTH2/DP2 (Ki = 5.3 and 5.0nM against human & murine DP2, respectively), exhibiting much reduced potency against a panel of more than 50 other receptors and ion channels. Effectively inhibits DP2-dependent chemotaxis of primary human eosinophils (IC50 = 100nM). Exhibits higher Caco-2 permeability than DP2 Antagonist I, but less oral bioavailability in mice. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??Cl?FN?O?. US Biological Life Sciences. | Worldwide |
| Fevipiprant | Fevipipran is a reversible competitive CRTh2 antagonist with IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. Now it is in Phase III clinical trials for the treatment of asthma. Uses: Allergic asthma; atopic dermatitis. Synonyms: NVP-QAW039; NVP-QAW 039; NVP-QAW-039 QAW-039; QAW039; QAW 039; Fevipiprant; 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid. Grades: 98%. CAS No. 872365-14-5. Molecular formula: C19H17F3N2O4S. Mole weight: 426.41. | |
| Imetit dihydrobromide | Imetit dihydrobromide is a potent and high affinity agonist at histamine H3 and H4 receptors (Ki = 0.3 and 2.7 nM, respectively). It induces an eosinophil shape change (EC50 = 25 nM). Synonyms: 5-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide. Grades: ≥98% by HPLC. CAS No. 32385-58-3. Molecular formula: C6H10N4S.2HBr. Mole weight: 332.06. | |
| JNJ 10191584 maleate | The maleate salt form of JNJ 10191584, which has been found to be a selective histamine H4 receptor silent antagonist and could restrain mast cell and eosinophil chemotaxis in vitro. Synonyms: VUF6002; VUF 6002; VUF-6002; JNJ-10191584 maleate; JNJ 10191584 maleate; JNJ10191584 maleate; 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate. Grades: ≥99% by HPLC. CAS No. 869497-75-6. Molecular formula: C13H15ClN4O.C4H4O4. Mole weight: 394.81. | |
| LY255283 | This active molecular is a competitive leukotriene B4 receptor antagonist and IC50 value is about 100 nM. LY 255283 is selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM. It also inhibits the binding of radiolabeled LTB4 to eosinophil membranes and IC50 value is 260 nM. LY255283 reduces airway obstruction in animal models of asthma. However, clinical trials for asthma had been discontinued. Uses: Asthma. Synonyms: LY 255283; LY255283; LY-255283; (1-(5-Ethyl-2-hydroxy-4-(6-methyl-6-(1H-tetrazol-5-yl)heptyloxy)phenyl)ethanone). Grades: 98%. CAS No. 117690-79-6. Molecular formula: C19H28N4O3. Mole weight: 360.45. | |
| LY 255283 | LY255283, a competitive leukotriene B4 receptor antagonist, is used in leukotriene receptor research along with other selective leukotriene receptor agonists and antagonist to identify and differentiate the physiological and cell signaling effects of the leukotriene B4 receptor on processes such as paclitaxel resistance in MCF-7/DOX breast cancer cells, monocyte-derived dendritic cell chemotaxis, and 5-lipoxygenase activity and interleukin-8 production in human neutrophils. LY255283 may be used to help verify that an observed process or cell event is leukotriene B4 receptor-dependent.Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4) have been potential drug development targets for several years.1,2 The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100nM.3 LY255283 exhibits IC50 values of ~950nM and >10uM at human recombinant BLT2 and BLT1 receptors, respectively.4 LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10uM, and inhibits the binding of radiolabeled LTB4 to eosinophil membranes with an IC50 of 260nM.1. Group: Biochemicals. Alternative Names: 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]-ethanone. Grades: Highly Purified. CAS No. 117690-79-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H28N4O3, Molecular Weight: 360.5. US Biological Life Sciences. | Worldwide |
| Nα-Boc-L-tryptophan | Nα-Boc-L-tryptophan is an N-Boc-protected form of L-Tryptophan. L-Tryptophan is an essential amino acid that is important for cell proliferation and the biosynthesis of proteins. It is a precursor to Serotonin, a neurotransmitter that aids in sleep and mental state. L-Tryptophan is also thought to cause eosinophilia-myalgia syndrome. Synonyms: Boc-L-Trp-OH; N-[(tert-Butoxy)carbonyl]-L-tryptophan; N-(tert-Butoxycarbonyl)-L-tryptophan; (S)-2-((tert-Butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoic acid; (2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid; Nalpha-Boc-L-Tryptophane; N-Boc-L-tryptophan. Grades: ≥ 99% (HPLC). CAS No. 13139-14-5. Molecular formula: C16H20N2O4. Mole weight: 304.30. | |
| reslizumab | Reslizumab is a humanized monoclonal antibody resistant to interleukin-5 (IL-5). It is approved for additional maintenance treatment of patients with severe asthma aged 18 years and older, and with an eosinophilic phenotype. Uses: The treatment of severe asthma. Synonyms: Cinqair. CAS No. 241473-69-8. | |
| Timapiprant | Timapiprant is a potent and selective D prostanoid receptor 2 (DP2; CRTH2) antagonist. It effectively improves lung function and symptoms in patients with atopic eosinophilic asthma. It was shown to reduce both nasal and eye symptoms in allergic subjects exposed to grass pollen. Synonyms: OC-000459; OC 000459; OC000459; 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid. CAS No. 851723-84-7. Molecular formula: C21H17FN2O2. Mole weight: 348.37. | |
| Timapiprant | Timapiprant / OC000459 is a potent, selective and orally active CRTH2 antagonist. It inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils. And it appears to inhibit allergic inflammation in asthma. Group: Fluorinated apis. Alternative Names: OC000459. CAS No. 851723-84-7. Molecular formula: C21H17FN2O2. Mole weight: 348.38. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid. Catalog: OFC851723847. | |
| Timapiprant sodium | Timapiprant is a potent and selective D prostanoid receptor 2 (DP2; CRTH2) antagonist. It effectively improves lung function and symptoms in patients with atopic eosinophilic asthma. It was shown to reduce both nasal and eye symptoms in allergic subjects exposed to grass pollen. Synonyms: OC-000459 sodium; OC 000459 sodium; OC000459 sodium; sodium 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetate. CAS No. 950688-14-9. Molecular formula: C21H16FN2NaO2. Mole weight: 370.35. | |
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