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| Product | Description | |
|---|---|---|
| Epipodophyllotoxin | Epipodophyllotoxin. Group: Biochemicals. Alternative Names: (5R, 5aR, 8aR, 9S) -5, 8, 8a, 9-Tetrahydro-9-hydroxy-5- (3, 4, 5-trimethoxyphenyl) furo[3', 4': 6, 7]naphtho[2, 3-d]-1, 3-dioxol-6 (5aH) -one; [5R-(5α,5a β,8aα,9 β ) ]-5, 8, 8a, 9-Tetrahydro-9-hydroxy-5- (3, 4, 5-trimethoxyphenyl) furo[3', 4': 6, 7]naphtho[2, 3-d]-1, 3-dioxol-6 (5aH) -one. Grades: Highly Purified. CAS No. 4375-7-9. Pack Sizes: 100mg. Molecular Formula: C22H22O8, Molecular Weight: 414.41. US Biological Life Sciences. |  Worldwide |
| 4'-De methyl epipodophyllotoxin | 4'-De methyl epipodophyllotoxin. Group: Biochemicals. Alternative Names: 4'-DMEP. Grades: Highly Purified. CAS No. 6559-91-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H20O8. US Biological Life Sciences. | Worldwide |
| 4'Demethyl epipodophyllotoxin | 4'-DMEP. inhibitor of microtubule assembly. CAS No. 6559-91-7. Product ID: 1-01474. Molecular formula: C21H20O8. Mole weight: 400.39. Purity: contains approximately 5% residual H2O and CH3OH. Categories: 4' Demethylepipodophyllotoxin. |  |
| 4'-De methyl epipodophyllotoxin (4'-DMEP) | A potent inhibitor of microtubule assembly. Group: Biochemicals. Alternative Names: 4'-DMEP. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4'-De methyl epipodophyllotoxin 99+% (HPLC) | 4'-De methyl epipodophyllotoxin 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| (-)-Epipodophyllotoxin | (-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum , with GI 50 s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro [1]. Uses: Scientific research. Group: Natural products. CAS No. 4375-7-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7654. |  |
| Etoposide | An antitumor agent. A topoisomerase II inhibitor. A derivative of podophyllotoxin that has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in human T cells, mouse thymocytes, and HL-60 human leukemia cells. Group: Biochemicals. Alternative Names: 4?-De methyl epipodophyllotoxin; 9-(4,6-O-ethylidene- β-D-glucopyranoside); (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene- β -D-glucopyranosyl]oxy]-5, 8, 8a, 9-tetrahydro-5- (4-hydroxy-3, 5-dimethoxyphenyl) furo[3, 4: 6, 7]naphtho[2, 3-d]-1, 3-dioxol-6 (5aH) -one; EPEG; VP 16-213; VePesid; Vepesid J; Zuyeyidal; trans-Etoposide. Grades: Highly Purified. CAS No. 33419-42-0. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??O??, Molecular Weight: 588.56. US Biological Life Sciences. | Worldwide |
| Etoposide | synthetic, 98.0-105.0%, powder. Group: Fluorescence/luminescence spectroscopyapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Eposin, Topok, Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-beta-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5alpha,5abeta,8aalpha,9beta(R*)]]-, VP 16 (pharmaceutical), 4'-Demethyl-1-O-[4,6-O-(ethylidene)-beta-D-glucopyranosyl]epipodophyllotoxin, Bioposide, Epipodophyllotoxin VP 16213, VP 16-123, Furo[3',4':6,7]naphtho[2,3-d]-1,3-. |  |
| Etoposide, 95.0-105.0% (HPLC) USP | Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcrip- tion and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells. Group: Biochemicals. Alternative Names: 4-Des methyl epipodophyllotoxin; VP-16-213, NSC 141540. Grades: USP. CAS No. 33419-42-0. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Illudin S | Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Illudin S; DR-15978; DR 15978; DR15978; NSC 626369; NSC-626369; NSC626369; Lunamycin; Lampterol. Product Category: Others. Appearance: Solid powder. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. Purity: 0.98. IUPACName: (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3'-dihydrospiro[cyclopropane-1,5'-inden]-7'(6'H)-one. Canonical SMILES: CC1=C2[C@H]([C@](CO)(C=C2C([C@](O)(C13CC3)C)=O)C)O. Product ID: ACM1149991. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Lignan P | Lignan P. Group: Biochemicals. Alternative Names: (5R,5aR,8aR,9S)-9-( β-D-Glucopyranosyloxy)-5, 8, 8a, 9-tetrahydro-5-(4-hydroxy-3, 5-dimethoxyphenyl)-uro[3', 4':6, 7]naphtho[2, 3-d]-1, 3-dioxol-6(5aH)-one; β -D-4'-De methyl epipodophyllotoxin Glucopyranoside; 4-De methyl epipodophyllotoxin 7'-O- β-D-glucopyranoside; 4'-De methyl epipodophyllotoxin glucoside; Pptoxin II. Grades: Highly Purified. CAS No. 23363-35-1. Pack Sizes: 50mg. Molecular Formula: C27H30O13, Molecular Weight: 562.52. US Biological Life Sciences. | Worldwide |
| Lignan P-d3 | Lignan P-d3. Group: Biochemicals. Alternative Names: (5R,5aR,8aR,9S)-9-( β-D-Glucopyranosyloxy)-5, 8, 8a, 9-tetrahydro-5-(4-hydroxy-3, 5-dimethoxyphenyl)-uro[3', 4':6, 7]naphtho[2, 3-d]-1, 3-dioxol-6(5aH)-one-d3; β -D-4'-De methyl epipodophyllotoxin Glucopyranoside; 4-De methyl epipodophyllotoxin 7'-O- β-D-glucopyranoside-d3; 4'-De methyl epipodophyllotoxin glucoside-d3; Pptoxin II-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C27H30O13, Molecular Weight: 562.52. US Biological Life Sciences. | Worldwide |
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