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exo-IWR 1 exo-IWR 1. Group: Biochemicals. Grades: Purified. CAS No. 1127442-87-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
exo-IWR 1 exo-IWR 1, the enantiomer of IWR-1 and the diastereomer of IWR-1-endo, is a potent SAR anticancer Wnt response inhibitor, which is a kind of small secreted proteins and are active in tissue homeostasis, tumorigenesis and embryonic development. It shows decreased activity against the Wnt/β-catenin pathway. It may be an ideal control for tests involving the active form, IWR-1-endo. It may be used in the treatment of some diseases and conditions such as degenerative diseases, cancers, osteopetrosis and type II diabetes. Synonyms: rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide; 4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: ≥99% by HPLC. CAS No. 1127442-87-8. Molecular formula: C25H19N3O3. Mole weight: 409.44. BOC Sciences 10
exo-IWR-1 exo-IWR-1. Group: Biochemicals. Alternative Names: rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: Highly Purified. CAS No. 1127442-87-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C25H19N3O3. US Biological Life Sciences. USBiological 7
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