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| Product | Description | |
|---|---|---|
| Fasudil hydrochloride | Fasudil HCl, a 5-isoquinolinesulfonamide derivative, is a highly selective Rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Uses: Fasudil hcl, a 5-isoquinolinesulfonamide derivative, is a highly selective rho-associated protein kinase inhibitor that might have a rate in romoting the recovery of neurological function, reducing clinical symptoms and the morbidity. Synonyms: Fasudil HCl; Eril; Fasudil (Hydrochloride); Fasudil Monohydrochloride; AT-877; HA-1077; AT 877; HA 1077; AT877; HA1077. Grades: >98%. CAS No. 105628-07-7. Molecular formula: C14H18ClN3O2S. Mole weight: 327.83. |  |
| Fasudil Hydrochloride | 5-(1,4-Diazepane-1-sulfonyl)isoquinoline;Eril. anti-ulcer, gastrointestinal-emptying agent enhances motility in the upper gastrointestinal tract. Grades: CP. CAS No. 105628-07-7. Product ID: 8-04677. Molecular formula: C14H17N3O2S.HCl. Mole weight: 327.84. Purity: 0.99. Reference: J. Pharmacol. Sci, 108, 301, 2008. |  |
| Fasudil Hydrochloride | Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 μM for ROCK1 , IC 50 s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil Hydrochloride is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HA-1077 Hydrochloride; AT-877 Hydrochloride. CAS No. 105628-07-7. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-10341. |  |
| Hydroxyfasudil Hydrochloride | Hydroxyfasudil Hydrochloride, an active metabolite of Fasudil, preferentially inhibits Rho-kinase and plays a central role in the pathogenesis of coronary artery spasm. It is reported to inhibit neutrophil migration and exhibit potent vasodilatory effects in vivo. Synonyms: HA 1100 hydrochloride; HA1100 hydrochloride; HA-1100 hydrochloride; 5-(1,4-diazepan-1-ylsulfonyl)-2~{H}-isoquinolin-1-one hydrochloride; 1-[(1,2-Dihydro-1-oxo-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine hydrochloride. Grades: >98%. CAS No. 155558-32-0. Molecular formula: C14H18ClN3O3S. Mole weight: 343.826. | |
| Hydroxy Fasudil Hydrochloride | A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo. Group: Biochemicals. Alternative Names: 1- (1-Hydroxy-5-isoquinolinesulfonyl) homopiperazine Hydrochloride; 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone; HA1100 Hydrochloride. Grades: Highly Purified. CAS No. 155558-32-0. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Fasudil Impurity 3 | An impurity of Fasudil. Fasudil is Ccyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor. Synonyms: Isoquinoline, 8-[(hexahydro-1H-1,?4-diazepin-1-yl)?sulfonyl]?-, hydrochloride. Grades: > 95%. CAS No. 166895-80-3. Molecular formula: C14H17N3O2S. HCl. Mole weight: 291.37 36.46. | |
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