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| Product | Description | |
|---|---|---|
| Fatostatin (2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole) | Cell-permeable. Blocks adipogenesis by inhibiting the activation of SREBPs (Sterol Regulatory Binding Proteins). Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Prevents increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 298197-04-3. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Fatostatin A | Fatostatin (125B11) is an inhibitor of SREBP activation and prevents SCAP-mediated escort of SREBP-1 or SREBP-2 to the Golgi (IC50 = 5.6 μM). Fatostatin has anti-tumor properties and can reduce hyperglycemia in ob/ob mice. Synonyms: Fatostatin; 4-(4-Methylphenyl)-2-(2-Propyl-4-Pyridinyl)Thiazole; 125B11. Grades: 98%. CAS No. 125256-00-0. Molecular formula: C18H18N2S. Mole weight: 294.4. |  |
| Fatostatin A | Fatostatin A. Group: Biochemicals. Grades: Purified. CAS No. 298197-04-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Fatostatin A hydrobromide | Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic (ob/ob) mice, and inhibits proliferation in DU 145 cells independently of IGF-1 signaling (IC50 = 0.1 μM). Uses: The treatment of some metabolic disorders. Synonyms: Fatostatin A; 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide; 2-Propyl-4-(4-p-tolyl-thiazol-2-yl)-pyridine. Grades: ≥97% by HPLC. CAS No. 298197-04-3. Molecular formula: C18H18N2S.HBr. Mole weight: 375.33. | |
| Fatostatin A Hydrobromide | Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP). Fatostatin A reverses hyperglycemia in diabetic mice. Cell permeable. Fatostatin A is used for the treatment and/or prevention of one or more metabolic disorders. Group: Biochemicals. Alternative Names: 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine Monohydrobromide. Grades: Highly Purified. CAS No. 298197-04-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Fatostatin hydrobromide | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| FGH10019 | FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, 5-10 times lower than the IC50 of fatostatin (~10 μM). Synonyms: FGH10019;FGH 10019; FGH-10019. Grades: >98%. CAS No. 1046045-61-7. Molecular formula: C18H19N3O2S2. Mole weight: 373.49. | |
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