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This molecular is a prodrug of ACT-246475 which is a selective P2Y12 receptor antagonist with a wider therapeutic window in the rat model. ACT-281959 is the phosphate of ACT-246475 and showed antithrombotic efficacy after oral administration in the rat ferric chloride model. In May 2016, Phase-I development is ongoing in France. Uses: Cardiovascular disorders;antithrombotic. Synonyms: ACT-281959; ACT 281959; ACT281959. butyl 4- ( (R) -3- (bis ( ( (isopropoxycarbonyl) oxy) methoxy) phosphoryl) -2- (6- ( (S) -3-methoxypyrrolidin-1-yl) -2-phenylpyrimidine-4-carboxamido) propanoyl) piperazine-1-carboxylate. Grades: 98%. CAS No. 1159501-31-1. Molecular formula: C38H55N6O14P. Mole weight: 850.86.
Ferric citrate
Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iron(III) citrate; Zerenex. CAS No. 3522-50-7. Pack Sizes: 100 mg. Product ID: HY-N1428C.
Ferric citrate hydrate
Ferric citrate hydrate, an orally active iron supplement, is an efficacious phosphate binder. Ferric citrate hydrate can be used for iron deficiency anemia and chronic kidney disease (CKD) research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2338-5-8. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-47030.
Iron(III) nitrate nonahydrate
Ferric nitrate nonahydrate is used in the determination of phosphate. Group: Metal & ceramic materials. Alternative Names: Ferric nitrate nonahydrate. CAS No. 7782-61-8. Molecular formula: FeH18N3O18. Mole weight: 404. Appearance: White to gray or light purple solid. Purity: 99%+. IUPACName: Iron(3+);trinitrate;nonahydrate. Canonical SMILES: [N+](=O)([O-])[O-]. [N+](=O)([O-])[O-]. [N+](=O)([O-])[O-]. O. O. O. O. O. O. O. O. O. [Fe+3]. Density: 1.68 g/cm³. ECNumber: 616-509-1. Catalog: ACM7782618-2.
Iron(III) nitrate nonahydrate
Iron(III) nitrate nonahydrate. Uses: Ferric nitrate nonahydrate is used in the determination of phosphate. Group: Electrolytesphosphors - phosphor materials. Alternative Names: Ferric nitrate nonahydrate. CAS No. 7782-61-8. Product ID: Iron(3+); trinitrate; nonahydrate. Molecular formula: 404. Mole weight: FeH18N3O18. [N+](=O)([O-])[O-]. [N+](=O)([O-])[O-]. [N+](=O)([O-])[O-]. O. O. O. O. O. O. O. O. O. [Fe+3]. InChI=1S/Fe.3NO3.9H2O/c; 3*2-1(3)4; /h; 9*1H2/q+3; 3*-1. SZQUEWJRBJDHSM-UHFFFAOYSA-N. 99%+.
NADPH dehydrogenase (quinone)
A flavoprotein. The enzyme from Escherichia coli is specific for NADPH and is most active with quinone derivatives and ferricyanide as electron acceptors.Menaquinone can act as acceptor. The enzyme from hog liver is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol. Group: Enzymes. Synonyms: reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase; NADPH oxidase; NADPH2 dehydrogenase (quinone). Enzyme Commission Number: EC 1.6.5.10. CAS No. 37256-37-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1588; NADPH dehydrogenase (quinone); EC 1.6.5.10; 37256-37-4; reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase; NADPH oxidase; NADPH2 dehydrogenase (quinone). Cat No: EXWM-1588.
Native Cystathionine-β-synthase
Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria. Human cbs performs a crucial step in the biosynthetic pathway of cysteine by providing a regulatory control po...nates methyl groups to a variety of substrates, e.g., neurotransmitters, proteins, and nucleic acids. in mammals, cbs is a highly regulated enzyme, which contains a heme cofactor that functions as a redox sensor, that can modulate its activity in response to changes in the redox potential. if the resting form of cbs in the cell has ferrous heme, the potential exists for activating the enzyme under oxidizing conditions by conversion to the ferric state. Group: Enzymes. Synonyms: Cystathionine-β-synthase; CBS; EC 4.2.1.22; 9023-99-8. Enzyme Commission Number: EC 4.2.1.22. CAS No. 9023-99-8. CBS. Cystathionine-β-synthase; CBS; EC 4.2.1.22; 9023-99-8. Cat No: DIA-272.
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