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| Product | Description | |
|---|---|---|
| Finerenone | Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist ( IC 50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 94-8862. CAS No. 1050477-31-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111372. |  |
| Finerenone | Finerenone is a non-steroidal antimineralocorticoid. It has less relative affinity to other steroid hormone receptors than currently available, which should result in fewer adverse effects like impotence, gynaecomastia and low sex drive. It was developed by BAyer. It is in phase III clinical trials for the treatment of chronic heart failure, chronic kidney disease and diabetic nephropathy. Uses: Finerenone was used for the treatment of chronic heart failure, chronic kidney disease and diabetic nephropathy. Synonyms: (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide;BAY94-8862;BAY-94-8862;BAY948862;BAY-948862. Grades: >98 %. CAS No. 1050477-31-0. Molecular formula: C21H22N4O3. Mole weight: 378.43. |  |
| Finerenone | Finerenone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide. CAS No. 1050477-31-0. Molecular formula: C21H22N4O3. Mole weight: 378.42. Catalog: APB1050477310. |  |
| Finerenone Impurity 1 | Finerenone Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide. CAS No. 1050477-27-4. Molecular formula: C21H22N4O3. Mole weight: 378.42. Catalog: APB1050477274. | |
| Finerenone Impurity 2 | Finerenone Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide. CAS No. 1050477-30-9. Molecular formula: C21H22N4O3. Mole weight: 378.42. Catalog: APB1050477309. | |
| Finerenone Impurity 29 | Finerenone Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid. CAS No. 1050477-45-6. Molecular formula: C21H21N3O4. Mole weight: 379.41. Catalog: APB1050477456. | |
| Finerenone Impurity 51 | Finerenone Impurity 51. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-cyanoethyl 2-(4-cyano-2-methoxybenzylidene)-3-oxobutanoate. CAS No. 1050477-39-8. Molecular formula: C16H14N2O4. Mole weight: 298.29. Catalog: APB1050477398. | |
| Finerenone impurity 52 | Finerenone impurity 52. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1050477-36-5. Molecular formula: C23H22N4O4. Mole weight: 418.45. Catalog: APB1050477365. | |
| Finerenone Impurity 52 | Finerenone Impurity 52. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate. CAS No. 1050477-43-4. Molecular formula: C22H20N4O4. Mole weight: 404.42. Catalog: APB1050477434. | |
| Finerenone Impurity 53 | Finerenone Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate. CAS No. 1050477-44-5. Molecular formula: C24H24N4O4. Mole weight: 432.47. Catalog: APB1050477445. | |
| 4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide | Synonyms: 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-; 4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-1,6-naphthyridine-3-carboxamide; (Rac)-Finerenone. Grades: ≥97%. CAS No. 1050477-27-4. Molecular formula: C21H22N4O3. Mole weight: 378.43. | |
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