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| Product | Description | |
|---|---|---|
| FK 866 hydrochloride | FK 866 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| FK 866 hydrochloride | FK 866 hydrochloride is a non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, visfatin, PBEF1) (Ki = 0.3 nM) and inhibits NAD biosynthesis. It induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ~1 nM)and induces apoptosis in four different neuroblastoma cell lines. FK 866 exhibits antineoplastic and antiangiogenic activities. Synonyms: FK-866 Hydrochloride; FK 866 Hydrochloride; FK866 Hydrochloride; 2-(E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 2727965-45-7. Molecular formula: C24H29N3O2.HCl. Mole weight: 427.97. |  |
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