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Fluprostenol is an F-series prostaglandin analog which demonstrates as a luteolytic in veterinary animals. Synonyms: 7-[(1R,2R,3R5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-(5Z)-heptenoic acid, methyl ester. Grades: ≥98%. CAS No. 73275-76-0. Molecular formula: C24H31F3O6. Mole weight: 472.5.
11-Keto fluprostenol
11-Keto fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Synonyms: Fluprostenol Prostaglandin D2; (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 62145-07-7. Molecular formula: C23H27F3O6. Mole weight: 456.5.
15(S)-Fluprostenol
15(S)-fluprostenol is less active as an FP agonist than 15(R)-fluprostenol. Synonyms: 16-(3-(Trifluoromethyl)phenoxy)-17,18,19,20-tetranor-2,3-cis-didehydro-pgf1-alpha; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 54276-24-3. Molecular formula: C23H29F3O6. Mole weight: 458.5.
(+)-Fluprostenol
(+)-Fluprostenol. Group: Biochemicals. Grades: Purified. CAS No. 54276-17-4. Pack Sizes: 1mg. US Biological Life Sciences.
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(+)-Fluprostenol
(+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 ( OVGP1 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54276-17-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108560.
15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15-Keto Fluprostenol isopropyl ester. CAS No. 404830-45-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-116617.
15-Keto Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; 15-keto Fluprostenol Isopropyl Ester. CAS No. 404830-45-1. Molecular formula: C26H33F3O6. Mole weight: 498.54.
17-Trifluoromethylphenyl trinor prostaglandin F2α
17-Trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. Synonyms: 17-trifluoromethylphenyl trinor PGF2α; (2R,3S,4R)-2-Ethyl-4-hydroxy-3-{(3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-en-1-yl}cyclopentyl. Grades: ≥98%. CAS No. 221246-34-0. Molecular formula: C24H31O5F3. Mole weight: 456.5.
AL 8810
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL-8810 produced a concentration-dependent shift in the fluprostenol concentration-response curve, without significantly decreasing the maximal response. AL-8810 has weak agonist potency with EC50 of 261 +/- 44 nM (n = 3) and Emax = 19% (relative to the full FP receptor agonist cloprostenol) in A7r5 cells and EC50 of 186 +/- 63 nM (n = 3) and Emax = 23% in 3T3 fibroblasts. Uses: Prostaglandin antagonists. Synonyms: AL-8810; 246246-19-5; AL 8810; AL8810; (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid; 12QE8J6004; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, (5Z)-; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propenyl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-. Grades: ≥98%. CAS No. 246246-19-5. Molecular formula: C24H31O4F. Mole weight: 402.5.
Dimethyl (3-phenoxy-2-oxoproyl)phosphonate
Dimethyl (3-phenoxy-2-oxoproyl)phosphonate Travopropst (T715600), a selective FP prostaglandin receptor agonist. Isopropyl ester of (+)-fluprostenol. Antiglaucoma. Used in the synthesis ofnovel prostanoid thromboxane A2 agonists. Group: Biochemicals. Alternative Names: P- (2-oxo-3-Phenoxypropyl) phosphonic Acid Dimethyl Ester; (2-oxo-3-Phenoxypropyl) phosphonic Acid Dimethyl Ester; (2-Oxo-3-phenoxypropyl) phosphonic Acid Dimethyl Ester; Dimethyl (2-oxo-3-phenoxypropyl) phosphonate; Dimethyl (3-Phenoxyacetonyl) phosphonate; Dimethyl 3-{Phenoxy-2-oxopropylphosphonate. Grades: Highly Purified. CAS No. 40665-68-7. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Travoprost
Selective FP prostaglandin receptor agonist. Isopropyl ester of (+)-fluprostenol. Antiglaucoma. Used to treat glaucoma. Group: Biochemicals. Alternative Names: (5Z) -7-[ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2-[ (1E, 3R) -3-hydroxy-4-[3- (trifluoromethyl) phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; AL 6221; Travaprost; Travatan. Grades: Highly Purified. CAS No. 157283-68-6. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??F?O?, Molecular Weight: 500.55. US Biological Life Sciences.
Worldwide
Travoprost
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fluprostenol isopropyl ester; AL6221; Flu-Ipr. CAS No. 157283-68-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0584.
Travoprost
Travoprost is a potent and selective FP prostaglandin receptor agonist used for the treatment of glaucoma. Synonyms: Travatan; Fluprostenol isopropyl ester; AL-6221; Flu-Ipr. Grades: >98%. CAS No. 157283-68-6. Molecular formula: C26H35F3O6. Mole weight: 500.55.
Travoprost Acid
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid; (+)-Fluprostenol; [1R-[1α(Z), 2β(1E, 3R*), 3α, 5α]]-7-[3, 5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid; AL 5848; 16-(m-Trifluoromethylphenoxy)-17,18,19,20-tetranorprostaglandin F2&alpha. Grades: 95%. CAS No. 54276-17-4. Molecular formula: C23H29F3O6. Mole weight: 458.48.
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