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| Product | Description | |
|---|---|---|
| Fmoc-Cys(Acm)-OH | Fmoc-Cys(Acm)-OH is a cysteine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 86060-81-3. Pack Sizes: 10 g; 25 g. Product ID: HY-W013143. |  |
| Fmoc-Cys(Acm)-OH | The side-chain Acm group is stable to TFA but can be removed with Hg(II) or Ag(I) to give cysteinyl peptides, or oxidatively with Tl(III) or I2 to generate cystinyl peptides. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(Acm)-OH, N-α-Fmoc-S-acetamidomethyl-L-cysteine. Product Category: Amino Acids. CAS No. 86060-81-3. Mole weight: 414.47. Product ID: ACM86060813. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Fmoc-Cys(Dpm)-OH | The Dpm group has increased stability compared to Trt, enabling selective removal of Mtt groups on the solid phase with dilute TFA without loss of Dpm groups. Furthermore, the Dpm group is removed by treatment with 95% TFA cleavage cocktails. Racemization during carboxyl activation is lower with this derivative than with Fmoc-Cys(Trt)-OH. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(Dpm)-OH, N-α-Fmoc-S-diphenylmethyl-L-cysteine. Product Category: Amino Acids. CAS No. 247595-29-5. Mole weight: 509.62. Product ID: ACM247595295. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-Cys(Mmt)-OH | Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS. Reference 4 describes a novel method for on-resin disulfide bond formation which uses Cys(Mmt) in combination with Cys(tBuS). Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(Mmt)-OH, N-α-Fmoc-S-p-methoxytrityl-L-cysteine. Product Category: Amino Acids. CAS No. 177582-21-7. Molecular formula: C38H33NO5S. Mole weight: 615.74. Product ID: ACM177582217. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-Cys(STmp)-OH | Fmoc-Cys(STmp)-OH is a novel new tool for the regioselective synthesis of multiple disulfide bridged peptides by Fmoc SPPS. The STmp group is stable to piperidine but is extremely easy to remove by mild thiolysis. Albericio has reported removing four STmp groups on the solid phase with only three 5 minute treatments of 0.1 M N-methylmorpholine (NMM) in DMF containing 5% DTT. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(STmp)-OH, N-α-Fmoc-S-2,4,6-trimethoxyphenylthio-L-cysteine. Product Category: Amino Acids. CAS No. 1403834-74-1. Molecular formula: C27H27NO7S2. Mole weight: 541.64. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2,4,6-trimethoxyphenyl)disulfanyl]propanoic acid. Canonical SMILES: COC1=CC(=C(C(=C1)OC)SSCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)OC. Density: 1.4±0.1 g/cm3. Product ID: ACM1403834741. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-Cys(tBu)-OH | The side-chain tBu group is stable to TFA and iodine oxidation. Treatment with MeSiCl3/PhSOPh removes t-Bu and cyclizes in one step without scrambling existing disulphide bonds. Removed with Hg(II) to give cysteinyl peptides. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(tBu)-OH, N-α-Fmoc-S-t.-butyl-L-cysteine. Product Category: Amino Acids. CAS No. 67436-13-9. Mole weight: 399.5. Product ID: ACM67436139. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-Cys(tButhio)-OH | Building block for introduction of cysteinyl residues by Fmoc SPPS. The t-Buthio group can be selectively removed using thiols or tributylphosphine. This protecting group is stable to TFA if thiol scavengers are not used. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(tButhio)-OH, N-α-Fmoc-S-t.-butylthio-L-cysteine. Product Category: Amino Acids. CAS No. 73724-43-3. Molecular formula: C22H25NO4S2. Mole weight: 431.57. Product ID: ACM73724433-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-Cys(THP)-OH | Fmoc-Cys(Thp)-OH is a new building block for Fmoc SPPS, in which the sulfhydryl group is protected with the acid-cleavable tetrahydropyranyl (Thp) group. The use of Fmoc-Cys(Thp)-OH has been shown to give superior results to the corresponding S-Trt, S-Dpm, S-Acm, and S-StBu derivatives. Uses: The identification and purity of fmoc-l-cys(thp)-oh can be determined through various analytical methods, including nuclear magnetic resonance (nmr) spectroscopy, high-resolution mass spectrometry (hr-ms), and hplc. these methods provide information on the molecular structure, molecular weight, and purity of the compound. Additional or Alternative Names: Fmoc-Cys(THP)-OH, N-α-Fmoc-S-(tetrahydropyranyl)-L-cysteine. Product Category: Amino Acids. CAS No. 1673576-83-4. Molecular formula: C23H25NO5S. Mole weight: 427.51. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(oxan-2-ylsulfanyl)propanoic acid. Canonical SMILES: C1CCOC(C1)SCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Product ID: ACM1673576834. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-Cys(Trt)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. The standard derivative for Fmoc SPPS of peptides containing Cys. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP, is to be employed, it is strongly recommended that collidine is used as the base , as this has been shown to significantly reduce loss of optical integrity during coupling. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(Trt)-OH, N-α-Fmoc-S-trityl-L-cysteine. Product Category: Amino Acids. CAS No. 103213-32-7. Molecular formula: C37H31NO4S. Mole weight: 585.71. Product ID: ACM103213327-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-hCys(Trt)-OH | Fmoc-homoCys(Trt)-OH is a useful tool for the introduction of homocysteine during Fmoc SPPS. It can be used in exactly the same manner as Fmoc-Cys(Trt)-OH. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-hCys(Trt)-OH, Fmoc-S-trityl-L-homocysteine. Product Category: Amino Acids. CAS No. 167015-23-8. Molecular formula: C38H33NO4S. Mole weight: 599.74. Product ID: ACM167015238. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-S-acetamidomethyl-L-penicillamine | Fmoc-S-acetamidomethyl-L-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: Fmoc-L-Pen(Acm)-OH; Fmoc-S-acetamidomethyl-β,β-dimethyl-L-Cys-OH; Fmoc-Pen(Acm)-OH; N-(fluorenylmethoxycarbonyl)-S-acetamidomethyl-L-penicillamine; (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-((acetamidomethyl)thio)-3-methylbutanoic acid; Fmoc-Cys(Me2)(Acm)-OH; 3-[(Acetamidomethyl)sulfanyl]-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-valine. Grades: ≥95%. CAS No. 201531-76-2. Molecular formula: C23H26N2O5S. Mole weight: 442.53. |  |
| Fmoc-S-diphenylmethyl-L-cysteine | The Dpm group has increased stability compared to Trt, enabling selective removal of Mtt groups on the solid phase with dilute TFA without loss of Dpm groups. Furthermore, the Dpm group is removed by treatment with 95% TFA cleavage cocktails. Racemization during carboxyl activation is lower with this derivative than with Fmoc-Cys(Trt)-OH. Uses: Fmoc solid-phase peptide synthesis. Additional or Alternative Names: Fmoc-Cys(Dpm)-OH, N-α-Fmoc-S-diphenylmethyl-L-cysteine. Product Category: Amino Acids. CAS No. 247595-29-5. Molecular formula: C31H27NO4S. Mole weight: 509.6. Product ID: ACM247595295-1. Alfa Chemistry ISO 9001:2015 Certified. | |
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